| Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway J Son, CA Lyssiotis, H Ying, X Wang, S Hua, M Ligorio, RM Perera, ... Nature 496 (7443), 101-105, 2013 | 2034 | 2013 |
| Autophagy in major human diseases DJ Klionsky, G Petroni, RK Amaravadi, EH Baehrecke, A Ballabio, P Boya, ... The EMBO journal 40 (19), e108863, 2021 | 1122 | 2021 |
| Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I K Yamamoto, A Venida, J Yano, DE Biancur, M Kakiuchi, S Gupta, ... Nature 581 (7806), 100-105, 2020 | 934 | 2020 |
| Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism RM Perera, S Stoykova, BN Nicolay, KN Ross, J Fitamant, M Boukhali, ... Nature 524 (7565), 361-365, 2015 | 817 | 2015 |
| Structural basis of membrane invagination by F-BAR domains A Frost, R Perera, A Roux, K Spasov, O Destaing, EH Egelman, ... Cell 132 (5), 807-817, 2008 | 655 | 2008 |
| The lysosome as a regulatory hub RM Perera, R Zoncu Annual review of cell and developmental biology 32 (1), 223-253, 2016 | 591 | 2016 |
| Stromal response to Hedgehog signaling restrains pancreatic cancer progression JJ Lee, RM Perera, H Wang, DC Wu, XS Liu, S Han, J Fitamant, PD Jones, ... Proceedings of the National Academy of Sciences 111 (30), E3091-E3100, 2014 | 553 | 2014 |
| Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex BM Castellano, AM Thelen, O Moldavski, MK Feltes, REN Van Der Welle, ... Science 355 (6331), 1306-1311, 2017 | 516 | 2017 |
| A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes R Zoncu, RM Perera, DM Balkin, M Pirruccello, D Toomre, P De Camilli Cell 136 (6), 1110-1121, 2009 | 405 | 2009 |
| Beige adipocyte maintenance is regulated by autophagy-induced mitochondrial clearance S Altshuler-Keylin, K Shinoda, Y Hasegawa, K Ikeda, H Hong, Q Kang, ... Cell metabolism 24 (3), 402-419, 2016 | 356 | 2016 |
| Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4, 5-bisphosphate R Zoncu, RM Perera, R Sebastian, F Nakatsu, H Chen, T Balla, G Ayala, ... Proceedings of the National Academy of Sciences 104 (10), 3793-3798, 2007 | 321 | 2007 |
| YAP inhibition restores hepatocyte differentiation in advanced HCC, leading to tumor regression J Fitamant, F Kottakis, S Benhamouche, HS Tian, N Chuvin, ... Cell reports 10 (10), 1692-1707, 2015 | 275 | 2015 |
| Pancreatic cancer metabolism: breaking it down to build it back up RM Perera, N Bardeesy Cancer discovery 5 (12), 1247-1261, 2015 | 222 | 2015 |
| Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth C Di Malta, D Siciliano, A Calcagni, J Monfregola, S Punzi, N Pastore, ... Science 356 (6343), 1188-1192, 2017 | 218 | 2017 |
| Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages RM Perera, R Zoncu, L Lucast, P De Camilli, D Toomre Proceedings of the National Academy of Sciences 103 (51), 19332-19337, 2006 | 206 | 2006 |
| NPC1-mTORC1 signaling couples cholesterol sensing to organelle homeostasis and is a targetable pathway in Niemann-Pick type C OB Davis, HR Shin, CY Lim, EY Wu, M Kukurugya, CF Maher, RM Perera, ... Developmental cell 56 (3), 260-276. e7, 2021 | 160 | 2021 |
| Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor–specific antibody generates enhanced … RM Perera, Y Narita, FB Furnari, HK Gan, C Murone, M Ahlkvist, ... Clinical Cancer Research 11 (17), 6390-6399, 2005 | 151 | 2005 |
| MiT/TFE family of transcription factors, lysosomes, and cancer RM Perera, C Di Malta, A Ballabio Annual review of cancer biology 3 (1), 203-222, 2019 | 141 | 2019 |
| The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics F Nakatsu, RM Perera, L Lucast, R Zoncu, J Domin, FB Gertler, D Toomre, ... Journal of Cell Biology 190 (3), 307-315, 2010 | 140 | 2010 |
| Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478 TG Johns, RB Luwor, C Murone, F Walker, J Weinstock, AA Vitali, ... Proceedings of the National Academy of Sciences 100 (26), 15871-15876, 2003 | 135 | 2003 |
Roberto ZoncuUniversity of California BerkeleyDirección de correo verificada de berkeley.edu
