Comprehensive functional genomic resource and integrative model for the human brain D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ... Science 362 (6420), eaat8464, 2018 | 934 | 2018 |
variancePartition: interpreting drivers of variation in complex gene expression studies GE Hoffman, EE Schadt BMC bioinformatics 17, 1-13, 2016 | 608 | 2016 |
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains D Demontis, GB Walters, G Athanasiadis, R Walters, K Therrien, ... Nature genetics 55 (2), 198-208, 2023 | 423 | 2023 |
Analysis of transcriptional variability in a large human iPSC library reveals genetic and non-genetic determinants of heterogeneity I Carcamo-Orive, GE Hoffman, P Cundiff, ND Beckmann, SL D’Souza, ... Cell stem cell 20 (4), 518-532. e9, 2017 | 263 | 2017 |
Four loci explain 83% of size variation in the horse S Makvandi-Nejad, GE Hoffman, JJ Allen, E Chu, E Gu, AM Chandler, ... PloS one 7 (7), e39929, 2012 | 256 | 2012 |
Synergistic effects of common schizophrenia risk variants N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ... Nature genetics 51 (10), 1475-1485, 2019 | 230 | 2019 |
CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder GE Hoffman, J Bendl, G Voloudakis, KS Montgomery, L Sloofman, ... Scientific data 6 (1), 180, 2019 | 225 | 2019 |
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk P Rajarajan, T Borrman, W Liao, N Schrode, E Flaherty, C Casiño, ... Science 362 (6420), eaat4311, 2018 | 218 | 2018 |
Dream: powerful differential expression analysis for repeated measures designs GE Hoffman, P Roussos Bioinformatics 37 (2), 192-201, 2021 | 215 | 2021 |
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk LM Huckins, A Dobbyn, DM Ruderfer, G Hoffman, W Wang, AF Pardinas, ... Nature genetics 51 (4), 659-674, 2019 | 198 | 2019 |
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ... Biological psychiatry 90 (9), 611-620, 2021 | 176 | 2021 |
Patterns of ancestry, signatures of natural selection, and genetic association with stature in Western African pygmies JP Jarvis, LB Scheinfeldt, S Soi, C Lambert, L Omberg, B Ferwerda, ... PLoS genetics 8 (4), e1002641, 2012 | 171 | 2012 |
Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains GE Hoffman, BJ Hartley, E Flaherty, I Ladran, P Gochman, DM Ruderfer, ... Nature communications 8 (1), 2225, 2017 | 161 | 2017 |
Landscape of conditional eQTL in dorsolateral prefrontal cortex and co-localization with schizophrenia GWAS A Dobbyn, LM Huckins, J Boocock, LG Sloofman, BS Glicksberg, ... The American Journal of Human Genetics 102 (6), 1169-1184, 2018 | 155 | 2018 |
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis BA Logsdon, GE Hoffman, JG Mezey BMC bioinformatics 11, 1-13, 2010 | 146 | 2010 |
Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome K Girdhar, GE Hoffman, Y Jiang, L Brown, M Kundakovic, ME Hauberg, ... Nature neuroscience 21 (8), 1126-1136, 2018 | 138 | 2018 |
Correcting for population structure and kinship using the linear mixed model: theory and extensions GE Hoffman PloS one 8 (10), e75707, 2013 | 133 | 2013 |
Neuronal impact of patient-specific aberrant NRXN1α splicing E Flaherty, S Zhu, N Barretto, E Cheng, PJM Deans, MB Fernando, ... Nature genetics 51 (12), 1679-1690, 2019 | 121 | 2019 |
Variants in TRIM22 that affect NOD2 signaling are associated with very-early-onset inflammatory bowel disease Q Li, CH Lee, LA Peters, LA Mastropaolo, C Thoeni, A Elkadri, T Schwerd, ... Gastroenterology 150 (5), 1196-1207, 2016 | 115 | 2016 |
Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19 JF Fullard, HC Lee, G Voloudakis, S Suo, B Javidfar, Z Shao, C Peter, ... Genome medicine 13, 1-13, 2021 | 113 | 2021 |