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Jonathan Bohlen
Jonathan Bohlen
Group Leader
Dirección de correo verificada de genzentrum.lmu.de - Página principal
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Selective 40S footprinting reveals cap-tethered ribosome scanning in human cells
J Bohlen, K Fenzl, G Kramer, B Bukau, AA Teleman
Molecular Cell 79 (4), 561-574. e5, 2020
1292020
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
Q Zhang, D Matuozzo, J Le Pen, D Lee, L Moens, T Asano, J Bohlen, ...
Journal of Experimental Medicine 219 (8), 2022
1112022
Translation acrobatics: how cancer cells exploit alternate modes of translational initiation
A Sriram, J Bohlen, AA Teleman
EMBO reports 19 (10), e45947, 2018
982018
DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4
J Bohlen, L Harbrecht, S Blanco, K Clemm von Hohenberg, K Fenzl, ...
Nature Communications 11 (1), 4676, 2020
752020
Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation
J Wang, BS Shin, C Alvarado, JR Kim, J Bohlen, TE Dever, JD Puglisi
Cell 185 (24), 4474-4487. e17, 2022
712022
Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe
G Kerner, AL Neehus, Q Philippot, J Bohlen, D Rinchai, N Kerrouche, ...
Cell Genomics 3 (2), 2023
642023
Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
J Rosain, AL Neehus, J Manry, R Yang, J Le Pen, W Daher, Z Liu, ...
Cell 186 (3), 621-645. e33, 2023
622023
Phosphorylation of ribosomal protein S6 differentially affects mRNA translation based on ORF length
J Bohlen, M Roiuk, AA Teleman
Nucleic acids research 49 (22), 13062-13074, 2021
612021
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
T Le Voyer, AV Parent, X Liu, A Cederholm, A Gervais, J Rosain, ...
Nature, 2023
592023
Impaired IL-23–dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency
M Ogishi, AA Arias, R Yang, JE Han, P Zhang, D Rinchai, J Halpern, ...
Journal of Experimental Medicine 219 (10), 2022
482022
Human IL-23 is essential for IFN-γ–dependent immunity to mycobacteria
Q Philippot, M Ogishi, J Bohlen, J Puchan, AA Arias, T Nguyen, ...
Science Immunology 8 (80), eabq5204, 2023
452023
DENR–MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation
YL Ahmed, S Schleich, J Bohlen, N Mandel, B Simon, I Sinning, ...
PLoS biology 16 (6), e2005160, 2018
392018
Targeting atypical protein kinase C iota reduces viability in glioblastoma stem‐like cells via a notch signaling mechanism
E Phillips, V Lang, J Bohlen, F Bethke, L Puccio, D Tichy, ...
International journal of cancer 139 (8), 1776-1787, 2016
372016
Cyclin B/CDK1 and Cyclin A/CDK2 phosphorylate DENR to promote mitotic protein translation and faithful cell division
K Clemm von Hohenberg, S Müller, S Schleich, M Meister, J Bohlen, ...
Nature Communications 13 (1), 668, 2022
312022
Human inherited CCR2 deficiency underlies progressive polycystic lung disease
AL Neehus, B Carey, M Landekic, P Panikulam, G Deutsch, M Ogishi, ...
Cell 187 (2), 390-408. e23, 2024
262024
PRRC2 proteins impact translation initiation by promoting leaky scanning
J Bohlen, M Roiuk, M Neff, AA Teleman
Nucleic Acids Research 51 (7), 3391-3409, 2023
222023
Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria
J Bohlen, Q Zhou, Q Philippot, M Ogishi, D Rinchai, T Nieminen, ...
Cell, 2023
192023
Translational control of E2f1 regulates the Drosophila cell cycle
JI Øvrebø, MR Bradley-Gill, N Zielke, M Kim, M Marchetti, J Bohlen, ...
Proceedings of the National Academy of Sciences 119 (4), e2113704119, 2022
182022
Gain-of-function human UNC93B1 variants cause systemic lupus erythematosus and chilblain lupus
C David, CA Arango-Franco, M Badonyi, J Fouchet, GI Rice, ...
Journal of Experimental Medicine 221 (8), 2024
172024
Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis
M Ogishi, R Yang, R Rodriguez, DP Golec, E Martin, Q Philippot, J Bohlen, ...
Journal of Experimental Medicine 220 (1), e20220484, 2022
162022
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Artículos 1–20