Appreciating force and shape—the rise of mechanotransduction in cell biology T Iskratsch, H Wolfenson, MP Sheetz Nature reviews Molecular cell biology 15 (12), 825-833, 2014 | 871 | 2014 |
Finding the weakest link–exploring integrin-mediated mechanical molecular pathways P Roca-Cusachs, T Iskratsch, MP Sheetz Journal of cell science 125 (13), 3025-3038, 2012 | 326 | 2012 |
Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices H Wolfenson, G Meacci, S Liu, MR Stachowiak, T Iskratsch, S Ghassemi, ... Nature cell biology 18 (1), 33-42, 2016 | 212 | 2016 |
Specificity analysis of lectins and antibodies using remodeled glycoproteins T Iskratsch, A Braun, K Paschinger, IBH Wilson Analytical Biochemistry 386 (2), 133-146, 2009 | 156 | 2009 |
Cardiomyocytes sense matrix rigidity through a combination of muscle and non-muscle myosin contractions P Pandey, W Hawkes, J Hu, WV Megone, J Gautrot, N Anilkumar, ... Developmental cell 44 (3), 326-336. e3, 2018 | 147 | 2018 |
Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance T Iskratsch, S Lange, J Dwyer, AL Kho, C Remedios, E Ehler Journal of Cell Biology 191 (6), 1159-1172, 2010 | 135 | 2010 |
FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration T Iskratsch, CH Yu, A Mathur, S Liu, V Stévenin, J Dwyer, J Hone, E Ehler, ... Developmental cell 27 (5), 545-559, 2013 | 121 | 2013 |
Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells E Tabdanov, S Gondarenko, S Kumari, A Liapis, ML Dustin, MP Sheetz, ... Integrative Biology 7 (10), 1272-1284, 2015 | 110 | 2015 |
Polymer fiber-based models of connective tissue repair and healing NM Lee, C Erisken, T Iskratsch, M Sheetz, WN Levine, HH Lu Biomaterials 112, 303-312, 2017 | 99 | 2017 |
α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions G Meacci, H Wolfenson, S Liu, MR Stachowiak, T Iskratsch, A Mathur, ... Molecular biology of the cell 27 (22), 3471-3479, 2016 | 88 | 2016 |
Early events in cell spreading as a model for quantitative analysis of biomechanical events H Wolfenson, T Iskratsch, MP Sheetz Biophysical journal 107 (11), 2508-2514, 2014 | 76 | 2014 |
Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and-861 AR Pedrosa, N Bodrug, J Gomez-Escudero, EP Carter, LE Reynolds, ... Cancer research 79 (17), 4371-4386, 2019 | 61 | 2019 |
Two distinct phosphorylation events govern the function of muscle FHOD3 T Iskratsch, S Reijntjes, J Dwyer, P Toselli, IR Dégano, I Dominguez, ... Cellular and Molecular Life Sciences 70, 893-908, 2013 | 59 | 2013 |
The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction DGS Wilson, A Tinker, T Iskratsch Communications Biology 5 (1), 1022, 2022 | 57 | 2022 |
Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing E Marhuenda, C Fabre, C Zhang, M Martin-Fernandez, T Iskratsch, ... Journal of Experimental & Clinical Cancer Research 40 (1), 139, 2021 | 55 | 2021 |
Mix and (mis-) match–The mechanosensing machinery in the changing environment of the developing, healthy adult and diseased heart M Ward, T Iskratsch Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (3), 118436, 2020 | 51 | 2020 |
Probing the nanoscale organisation and multivalency of cell surface receptors: DNA origami nanoarrays for cellular studies with single-molecule control W Hawkes, D Huang, P Reynolds, L Hammond, M Ward, N Gadegaard, ... Faraday Discussions 219, 203-219, 2019 | 50 | 2019 |
Endoplasmic Spreading Requires Coalescence of Vimentin Intermediate Filaments at Force-Bearing Adhesions CD Lynch, AM Lazar, T Iskratsch, X Zhang, MP Sheetz Molecular Biology of the Cell, 2012 | 50 | 2012 |
N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading X Zhang, SW Moore, T Iskratsch, MP Sheetz Journal of cell science 127 (7), 1394-1405, 2014 | 38 | 2014 |
Mammalian cells contain a second nucleocytoplasmic hexosaminidase M Gutternigg, D Rendić, R Voglauer, T Iskratsch, IBH Wilson Biochemical Journal 419 (1), 83-90, 2009 | 38 | 2009 |