| Intestinal ABCA1 directly contributes to HDL biogenesis in vivo LR Brunham, JK Kruit, J Iqbal, C Fievet, JM Timmins, TD Pape, ... The Journal of clinical investigation 116 (4), 1052-1062, 2006 | 662 | 2006 |
| Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I JM Timmins, JY Lee, E Boudyguina, KD Kluckman, LR Brunham, A Mulya, ... The Journal of clinical investigation 115 (5), 1333-1342, 2005 | 616 | 2005 |
| β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment LR Brunham, JK Kruit, TD Pape, JM Timmins, AQ Reuwer, Z Vasanji, ... Nature medicine 13 (3), 340-347, 2007 | 491 | 2007 |
| Regulated cell death pathways in doxorubicin-induced cardiotoxicity E Christidi, LR Brunham Cell Death & Disease 12 (4), 339, 2021 | 444 | 2021 |
| Efflux and Atherosclerosis: The Clinical and Biochemical Impact of Variations in the ABCA1 Gene RR Singaraja, LR Brunham, H Visscher, JJP Kastelein, MR Hayden Arteriosclerosis, thrombosis, and vascular biology 23 (8), 1322-1332, 2003 | 369 | 2003 |
| A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer F Aminkeng, AP Bhavsar, H Visscher, SR Rassekh, Y Li, JW Lee, ... Nature genetics 47 (9), 1079-1084, 2015 | 279 | 2015 |
| Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) AJ Vallejo-Vaz, CAT Stevens, ARM Lyons, KI Dharmayat, T Freiberger, ... The Lancet 398 (10312), 1713-1725, 2021 | 239 | 2021 |
| Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin LR Brunham, PJ Lansberg, L Zhang, F Miao, C Carter, GK Hovingh, ... The pharmacogenomics journal 12 (3), 233-237, 2012 | 236 | 2012 |
| Optimizing cholesterol treatment in patients with muscle complaints RS Rosenson, S Baker, M Banach, KM Borow, LT Braun, E Bruckert, ... Journal of the American College of Cardiology 70 (10), 1290-1301, 2017 | 227 | 2017 |
| Association of monogenic vs polygenic hypercholesterolemia with risk of atherosclerotic cardiovascular disease M Trinder, GA Francis, LR Brunham JAMA cardiology 5 (4), 390-399, 2020 | 218 | 2020 |
| Reducing the clinical and public health burden of familial hypercholesterolemia: a global call to action KA Wilemon, J Patel, C Aguilar-Salinas, CD Ahmed, M Alkhnifsawi, ... JAMA cardiology 5 (2), 217-229, 2020 | 197 | 2020 |
| Cholesterol in islet dysfunction and type 2 diabetes LR Brunham, JK Kruit, CB Verchere, MR Hayden The Journal of clinical investigation 118 (2), 403-408, 2008 | 195 | 2008 |
| HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus JK Kruit, LR Brunham, CB Verchere, MR Hayden Current opinion in lipidology 21 (3), 178-185, 2010 | 192 | 2010 |
| Variations on a Gene: Rare and Common Variants in ABCA1 and Their Impact on HDL Cholesterol Levels and Atherosclerosis LR Brunham, RR Singaraja, MR Hayden Annu. Rev. Nutr. 26 (1), 105-129, 2006 | 192 | 2006 |
| Modeling doxorubicin-induced cardiotoxicity in human pluripotent stem cell derived-cardiomyocytes A Maillet, K Tan, X Chai, SN Sadananda, A Mehta, J Ooi, MR Hayden, ... Scientific reports 6 (1), 25333, 2016 | 182 | 2016 |
| Accurate Prediction of the Functional Significance of Single Nucleotide Polymorphisms and Mutations in the ABCA1 Gene LR Brunham, RR Singaraja, TD Pape, A Kejariwal, PD Thomas, ... PLoS genetics 1 (6), e83, 2005 | 163 | 2005 |
| Risk of premature atherosclerotic disease in patients with monogenic versus polygenic familial hypercholesterolemia M Trinder, X Li, ML DeCastro, L Cermakova, S Sadananda, LM Jackson, ... Journal of the American College of Cardiology 74 (4), 512-522, 2019 | 162 | 2019 |
| Decreased high-density lipoprotein cholesterol level is an early prognostic marker for organ dysfunction and death in patients with suspected sepsis M Cirstea, KR Walley, JA Russell, LR Brunham, KR Genga, JH Boyd Journal of critical care 38, 289-294, 2017 | 162 | 2017 |
| Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function JM Karasinska, F Rinninger, D Lütjohann, P Ruddle, S Franciosi, JK Kruit, ... Journal of Neuroscience 29 (11), 3579-3589, 2009 | 161 | 2009 |
| Carriers of loss-of-function mutations in ABCA1 display pancreatic β-cell dysfunction M Vergeer, LR Brunham, J Koetsveld, JK Kruit, CB Verchere, ... Diabetes care 33 (4), 869-874, 2010 | 150 | 2010 |