Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase JT Garrett, MG Olivares, C Rinehart, ND Granja-Ingram, V Sánchez, ... Proceedings of the National Academy of Sciences 108 (12), 5021-5026, 2011 | 524 | 2011 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 464 | 2020 |
Transfer of functional cargo in exomeres Q Zhang, JN Higginbotham, DK Jeppesen, YP Yang, W Li, ET McKinley, ... Cell reports 27 (3), 940-954. e6, 2019 | 365 | 2019 |
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Q Zhang, DK Jeppesen, JN Higginbotham, R Graves-Deal, VQ Trinh, ... Nature cell biology 23 (12), 1240-1254, 2021 | 310 | 2021 |
Unsupervised trajectory analysis of single-cell RNA-seq and imaging data reveals alternative tuft cell origins in the gut CA Herring, A Banerjee, ET McKinley, AJ Simmons, J Ping, JT Roland, ... Cell systems 6 (1), 37-51. e9, 2018 | 220 | 2018 |
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps B Chen, S Cherie’R, ET McKinley, AJ Simmons, MA Ramirez-Solano, ... Cell 184 (26), 6262-6280. e26, 2021 | 210 | 2021 |
Succinate produced by intestinal microbes promotes specification of tuft cells to suppress ileal inflammation A Banerjee, CA Herring, B Chen, H Kim, AJ Simmons, AN Southard-Smith, ... Gastroenterology 159 (6), 2101-2115. e5, 2020 | 191 | 2020 |
MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging D Schapiro, A Sokolov, C Yapp, YA Chen, JL Muhlich, J Hess, ... Nature methods 19 (3), 311-315, 2022 | 174 | 2022 |
Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity ET McKinley, Y Sui, Y Al-Kofahi, BA Millis, MJ Tyska, JT Roland, ... JCI insight 2 (11), e93487, 2017 | 148 | 2017 |
Limits of [18F]-FLT PET as a Biomarker of Proliferation in Oncology ET McKinley, GD Ayers, RA Smith, SA Saleh, P Zhao, MK Washington, ... PloS one 8 (3), e58938, 2013 | 136 | 2013 |
Volume of preclinical xenograft tumors is more accurately assessed by ultrasound imaging than manual caliper measurements GD Ayers, ET McKinley, P Zhao, JM Fritz, RE Metry, BC Deal, KM Adlerz, ... Journal of Ultrasound in Medicine 29 (6), 891-901, 2010 | 133 | 2010 |
Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer HC Manning, NB Merchant, AC Foutch, JM Virostko, SK Wyatt, C Shah, ... Clinical cancer research 14 (22), 7413-7422, 2008 | 124 | 2008 |
In vivo imaging of cancer cell size and cellularity using temporal diffusion spectroscopy X Jiang, H Li, J Xie, ET McKinley, P Zhao, JC Gore, J Xu Magnetic resonance in medicine 78 (1), 156-164, 2017 | 115 | 2017 |
Imaging biomarkers predict response to anti-HER2 (ErbB2) therapy in preclinical models of breast cancer C Shah, TW Miller, SK Wyatt, ET McKinley, MG Olivares, V Sanchez, ... Clinical Cancer Research 15 (14), 4712-4721, 2009 | 101 | 2009 |
Magnetic resonance imaging of mean cell size in human breast tumors J Xu, X Jiang, H Li, LR Arlinghaus, ET McKinley, SP Devan, BM Hardy, ... Magnetic resonance in medicine 83 (6), 2002-2014, 2020 | 96 | 2020 |
Interpreting heterogeneity in intestinal tuft cell structure and function A Banerjee, ET McKinley, J von Moltke, RJ Coffey, KS Lau The Journal of clinical investigation 128 (5), 1711-1719, 2018 | 89 | 2018 |
Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2, 5-dimethoxybenzyl)-2-phenoxyaniline JR Buck, ET McKinley, MR Hight, A Fu, D Tang, RA Smith, MN Tantawy, ... Journal of Nuclear Medicine 52 (1), 107-114, 2011 | 73 | 2011 |
Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis AE Powell, G Vlacich, ZY Zhao, ET McKinley, MK Washington, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 307 (1 …, 2014 | 72 | 2014 |
Quantitative preclinical imaging of TSPO expression in glioma using N, N-diethyl-2-(2-(4-(2-18F-fluoroethoxy) phenyl)-5, 7-dimethylpyrazolo [1, 5-a] pyrimidin-3-yl) acetamide D Tang, MR Hight, ET McKinley, A Fu, JR Buck, RA Smith, MN Tantawy, ... Journal of Nuclear Medicine 53 (2), 287-294, 2012 | 71 | 2012 |
18FDG-PET Predicts Pharmacodynamic Response to OSI-906, a Dual IGF-1R/IR Inhibitor, in Preclinical Mouse Models of Lung Cancer ET McKinley, JE Bugaj, P Zhao, S Guleryuz, C Mantis, PC Gokhale, ... Clinical Cancer Research 17 (10), 3332-3340, 2011 | 61 | 2011 |