Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor α TPJ Garrett, NM McKern, M Lou, TC Elleman, TE Adams, GO Lovrecz, ... Cell 110 (6), 763-773, 2002 | 1119 | 2002 |
Extracellular vesicle isolation and characterization: toward clinical application R Xu, DW Greening, HJ Zhu, N Takahashi, RJ Simpson The Journal of clinical investigation 126 (4), 1152-1162, 2016 | 943 | 2016 |
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model HY Lan, W Mu, N Tomita, XR Huang, JH Li, HJ Zhu, R Morishita, ... Journal of the American Society of Nephrology 14 (6), 1535-1548, 2003 | 482 | 2003 |
Smad7 inhibits fibrotic effect of TGF-β on renal tubular epithelial cells by blocking Smad2 activation JH Li, HJ Zhu, XR Huang, KN Lai, RJ Johnson, HY Lan Journal of the American Society of Nephrology 13 (6), 1464-1472, 2002 | 437 | 2002 |
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer NI Fleming, RN Jorissen, D Mouradov, M Christie, A Sakthianandeswaren, ... Cancer research 73 (2), 725-735, 2013 | 411 | 2013 |
Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal … H Ji, DW Greening, TW Barnes, JW Lim, BJ Tauro, A Rai, R Xu, C Adda, ... Proteomics 13 (10-11), 1672-1686, 2013 | 383 | 2013 |
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling BJ Jenkins, D Grail, T Nheu, M Najdovska, B Wang, P Waring, M Inglese, ... Nature medicine 11 (8), 845-852, 2005 | 368 | 2005 |
Advanced glycation end products activate Smad signaling via TGF‐β‐dependent and‐independent mechanisms: implications for diabetic renal and vascular disease JH Li, XR Huang, HJ Zhu, M Oldfield, M Cooper, LD Truong, RJ Johnson, ... The FASEB Journal 18 (1), 176-178, 2004 | 335 | 2004 |
Heart and liver defects and reduced transforming growth factor β2 sensitivity in transforming growth factor β type III receptor-deficient embryos KL Stenvers, ML Tursky, KW Harder, N Kountouri, S Amatayakul-Chantler, ... Molecular and cellular biology 23 (12), 4371-4385, 2003 | 308 | 2003 |
Isolation and characterization of tumor cells from the ascites of ovarian cancer patients: molecular phenotype of chemoresistant ovarian tumors A Latifi, RB Luwor, M Bilandzic, S Nazaretian, K Stenvers, J Pyman, H Zhu, ... Public Library of Science 7 (10), e46858, 2012 | 279 | 2012 |
Emerging roles of exosomes during epithelial–mesenchymal transition and cancer progression DW Greening, SK Gopal, RA Mathias, L Liu, J Sheng, HJ Zhu, ... Seminars in cell & developmental biology 40, 60-71, 2015 | 263 | 2015 |
Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden K Abubaker, A Latifi, R Luwor, S Nazaretian, H Zhu, MA Quinn, ... Molecular cancer 12, 1-15, 2013 | 250 | 2013 |
Role of TGF-β signaling in extracellular matrix production under high glucose conditions JH Li, XR Huang, HJ Zhu, R Johnson, HY Lan Kidney international 63 (6), 2010-2019, 2003 | 245 | 2003 |
Regulation and function of protein kinases and phosphatases HC Cheng, RZ Qi, H Paudel, HJ Zhu Enzyme research 2011, 794089, 2011 | 234 | 2011 |
Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition BJ Tauro, RA Mathias, DW Greening, SK Gopal, H Ji, EA Kapp, ... Molecular & cellular proteomics 12 (8), 2148-2159, 2013 | 218 | 2013 |
Cancer associated-fibroblast-derived exosomes in cancer progression C Li, AF Teixeira, HJ Zhu, P Ten Dijke Molecular cancer 20 (1), 154, 2021 | 214 | 2021 |
Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling FF Zhou, Y Drabsch, TJA Dekker, AG De Vinuesa, Y Li, LJAC Hawinkels, ... Nature communications 5 (1), 3388, 2014 | 206 | 2014 |
TGF-β induces proangiogenic and antiangiogenic factorsvia parallel but distinct Smad pathways T Nakagawa, JH Li, G Garcia, W Mu, E Piek, EP Böttinger, Y Chen, ... Kidney international 66 (2), 605-613, 2004 | 205 | 2004 |
Regulation of transforming growth factor-β signaling HJ Zhu, AW Burgess Molecular cell biology research communications 4 (6), 321-330, 2001 | 187 | 2001 |
On-target anti-TGF-β therapies are not succeeding in clinical cancer treatments: what are remaining challenges? AF Teixeira, P Ten Dijke, HJ Zhu Frontiers in cell and developmental biology 8, 605, 2020 | 185 | 2020 |