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Alex Kreutzberger
Alex Kreutzberger
Harvard Medical School
Dirección de correo verificada de tklab.hms.harvard.edu - Página principal
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The role of cholesterol in membrane fusion
ST Yang, AJB Kreutzberger, J Lee, V Kiessling, LK Tamm
Chemistry and physics of lipids 199, 136-143, 2016
4672016
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
R Zang, JB Case, E Yutuc, X Ma, S Shen, MF Gomez Castro, Z Liu, ...
Proceedings of the National Academy of Sciences 117 (50), 32105-32113, 2020
2242020
HIV virions sense plasma membrane heterogeneity for cell entry
ST Yang, AJB Kreutzberger, V Kiessling, BK Ganser-Pornillos, JM White, ...
Science advances 3 (6), e1700338, 2017
1142017
SARS-CoV-2 requires acidic pH to infect cells
AJB Kreutzberger, A Sanyal, A Saminathan, LM Bloyet, S Stumpf, Z Liu, ...
Proceedings of the National Academy of Sciences 119 (38), e2209514119, 2022
922022
Variable cooperativity in SNARE-mediated membrane fusion
JM Hernandez, AJB Kreutzberger, V Kiessling, LK Tamm, R Jahn
Proceedings of the National Academy of Sciences 111 (33), 12037-12042, 2014
912014
Rhomboid distorts lipids to break the viscosity-imposed speed limit of membrane diffusion
AJB Kreutzberger, M Ji, J Aaron, L Mihaljević, S Urban
Science 363 (6426), eaao0076, 2019
892019
ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels
AK Narahari, AJB Kreutzberger, PS Gaete, YH Chiu, SA Leonhardt, ...
Elife 10, e64787, 2021
782021
High cholesterol obviates a prolonged hemifusion intermediate in fast SNARE-mediated membrane fusion
AJB Kreutzberger, V Kiessling, LK Tamm
Biophysical journal 109 (2), 319-329, 2015
602015
Reconstitution of calcium-mediated exocytosis of dense-core vesicles
AJB Kreutzberger, V Kiessling, B Liang, P Seelheim, S Jakhanwal, ...
Science Advances 3 (7), e1603208, 2017
592017
Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry
J Lee, AJB Kreutzberger, L Odongo, EA Nelson, D Nyenhuis, V Kiessling, ...
Biophysical Journal 120 (3), 191a, 2021
562021
A molecular mechanism for calcium-mediated synaptotagmin-triggered exocytosis
V Kiessling, AJB Kreutzberger, B Liang, SB Nyenhuis, P Seelheim, ...
Nature structural & molecular biology 25 (10), 911-917, 2018
502018
An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion
S Luo, J Zhang, AJB Kreutzberger, A Eaton, RJ Edwards, C Jing, HQ Dai, ...
Science immunology 7 (76), eadd5446, 2022
492022
In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties
AJB Kreutzberger, V Kiessling, C Stroupe, B Liang, J Preobraschenski, ...
Nature communications 10 (1), 3904, 2019
412019
Synergistic block of SARS-CoV-2 infection by combined drug inhibition of the host entry factors PIKfyve kinase and TMPRSS2 protease
AJB Kreutzberger, A Sanyal, R Ojha, JD Pyle, O Vapalahti, G Balistreri, ...
Journal of virology 95 (21), 10.1128/jvi. 00975-21, 2021
402021
Complexin binding to membranes and acceptor t-SNAREs explains its clamping effect on fusion
R Zdanowicz, A Kreutzberger, B Liang, V Kiessling, LK Tamm, DS Cafiso
Biophysical journal 113 (6), 1235-1250, 2017
402017
Asymmetric phosphatidylethanolamine distribution controls fusion pore lifetime and probability
AJB Kreutzberger, V Kiessling, B Liang, ST Yang, JD Castle, LK Tamm
Biophysical journal 113 (9), 1912-1915, 2017
372017
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein
K Yang, C Wang, AJB Kreutzberger, R Ojha, S Kuivanen, S Couoh-Cardel, ...
Proceedings of the National Academy of Sciences 119 (40), e2210990119, 2022
342022
Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP
SS Hussain, MT Harris, AJB Kreutzberger, CM Inouye, CA Doyle, ...
Molecular biology of the Cell 29 (10), 1238-1257, 2018
342018
Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2
AJB Kreutzberger, V Kiessling, CA Doyle, N Schenk, CM Upchurch, ...
Elife 9, e62506, 2020
332020
Unraveling the mechanisms of calcium-dependent secretion
A Anantharam, AJB Kreutzberger
Journal of General Physiology 151 (4), 417-434, 2019
332019
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Artículos 1–20