Combined delivery of temozolomide and anti‐miR221 PNA using mesoporous silica nanoparticles induces apoptosis in resistant glioma cells A Bertucci, EA Prasetyanto, D Septiadi, A Manicardi, E Brognara, ... Small 11 (42), 5687-5695, 2015 | 149 | 2015 |
Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development R Gambari, E Fabbri, M Borgatti, I Lampronti, A Finotti, E Brognara, ... Biochemical pharmacology 82 (10), 1416-1429, 2011 | 123 | 2011 |
Detection of unamplified genomic DNA by a PNA-based microstructured optical fiber (MOF) Bragg-grating optofluidic system A Bertucci, A Manicardi, A Candiani, S Giannetti, A Cucinotta, G Spoto, ... Biosensors and Bioelectronics 63, 248-254, 2015 | 114 | 2015 |
DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker K Gorska, A Manicardi, S Barluenga, N Winssinger Chemical Communications 47 (15), 4364-4366, 2011 | 99 | 2011 |
Modulation of the biological activity of microRNA‐210 with peptide nucleic acids (PNAs) E Fabbri, A Manicardi, T Tedeschi, S Sforza, N Bianchi, E Brognara, ... ChemMedChem 6 (12), 2192-2202, 2011 | 92 | 2011 |
Label-free DNA biosensor based on a peptide nucleic acid-functionalized microstructured optical fiber-Bragg grating A Candiani, A Bertucci, S Giannetti, M Konstantaki, A Manicardi, ... Journal of biomedical optics 18 (5), 057004-057004, 2013 | 86 | 2013 |
Peptide nucleic acids with a structurally biased backbone. Updated review and emerging challenges R Corradini, S Sforza, T Tedeschi, F Totsingan, A Manicardi, R Marchelli Current topics in medicinal chemistry 11 (12), 1535-1554, 2011 | 86 | 2011 |
Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells E Brognara, E Fabbri, F Aimi, A Manicardi, N Bianchi, A Finotti, ... International journal of oncology 41 (6), 2119-2127, 2012 | 85 | 2012 |
Cellular uptakes, biostabilities and anti‐miR‐210 activities of chiral arginine‐PNAs in leukaemic K562 cells A Manicardi, E Fabbri, T Tedeschi, S Sforza, N Bianchi, E Brognara, ... ChemBioChem 13 (9), 1327-1337, 2012 | 72 | 2012 |
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222 E Brognara, E Fabbri, G Montagner, J Gasparello, A Manicardi, ... International journal of oncology 48 (3), 1029-1038, 2016 | 71 | 2016 |
Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221 E Brognara, E Fabbri, E Bazzoli, G Montagner, C Ghimenton, A Eccher, ... Journal of neuro-oncology 118, 19-28, 2014 | 65 | 2014 |
Beyond small molecules: targeting G-quadruplex structures with oligonucleotides and their analogues E Cadoni, L De Paepe, A Manicardi, A Madder Nucleic Acids Research 49 (12), 6638-6659, 2021 | 63 | 2021 |
Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix [4] arene J Gasparello, A Manicardi, A Casnati, R Corradini, R Gambari, A Finotti, ... Scientific reports 9 (1), 3036, 2019 | 62 | 2019 |
Optical fiber sensors for label-free DNA detection M Barozzi, A Manicardi, A Vannucci, A Candiani, M Sozzi, M Konstantaki, ... Journal of Lightwave Technology 35 (16), 3461-3472, 2016 | 60 | 2016 |
Intracellular delivery of peptide nucleic acid and organic molecules using zeolite‐L nanocrystals A Bertucci, H Lülf, D Septiadi, A Manicardi, R Corradini, L De Cola Advanced healthcare materials 3 (11), 1812-1817, 2014 | 59 | 2014 |
A peptide nucleic acid against microRNA miR-145-5p enhances the expression of the cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 cells E Fabbri, A Tamanini, T Jakova, J Gasparello, A Manicardi, R Corradini, ... Molecules 23 (1), 71, 2017 | 56 | 2017 |
miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs E Fabbri, E Brognara, M Borgatti, I Lampronti, A Finotti, N Bianchi, ... Epigenomics 3 (6), 733-745, 2011 | 48 | 2011 |
Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells R Milani, E Brognara, E Fabbri, A Manicardi, R Corradini, A Finotti, ... International journal of oncology 55 (1), 59-68, 2019 | 41 | 2019 |
High levels of apoptosis are induced in the human colon cancer HT-29 cell line by co-administration of sulforaphane and a peptide nucleic acid targeting miR-15b-5p J Gasparello, L Gambari, C Papi, A Rozzi, A Manicardi, R Corradini, ... Nucleic acid therapeutics 30 (3), 164-174, 2020 | 39 | 2020 |
PNA-based microRNA detection methodologies E Cadoni, A Manicardi, A Madder Molecules 25 (6), 1296, 2020 | 39 | 2020 |