Remdesivir for the treatment of Covid-19—preliminary report JH Beigel, KM Tomashek, LE Dodd, AK Mehta, BS Zingman, AC Kalil, ... New England Journal of Medicine 383 (19), 1813-1836, 2020 | 2714 | 2020 |
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells BP Kleinstiver, SQ Tsai, MS Prew, NT Nguyen, MM Welch, JM Lopez, ... Nature biotechnology 34 (8), 869-874, 2016 | 748 | 2016 |
Operating characteristics of the rank-based inverse normal transformation for quantitative trait analysis in genome-wide association studies ZR McCaw, JM Lane, R Saxena, S Redline, X Lin Biometrics 76 (4), 1262-1272, 2020 | 209 | 2020 |
Using the restricted mean survival time difference as an alternative to the hazard ratio for analyzing clinical cardiovascular studies ZR McCaw, G Yin, LJ Wei Circulation 140 (17), 1366-1368, 2019 | 80 | 2019 |
Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration JK Krishnaswamy, A Singh, U Gowthaman, R Wu, P Gorrepati, ... Proceedings of the National Academy of Sciences 112 (10), 3056-3061, 2015 | 76 | 2015 |
Large-scale machine-learning-based phenotyping significantly improves genomic discovery for optic nerve head morphology B Alipanahi, F Hormozdiari, B Behsaz, J Cosentino, ZR McCaw, ... The American Journal of Human Genetics 108 (7), 1217-1230, 2021 | 59 | 2021 |
Utility of restricted mean survival time analysis for heart failure clinical trial evaluation and interpretation C Perego, M Sbolli, C Specchia, M Fiuzat, ZR McCaw, M Metra, ... Heart Failure 8 (12), 973-983, 2020 | 49 | 2020 |
How to quantify and interpret treatment effects in comparative clinical studies of COVID-19 ZR McCaw, L Tian, JL Vassy, CS Ritchie, CC Lee, DH Kim, LJ Wei Annals of internal medicine 173 (8), 632-637, 2020 | 48 | 2020 |
Inference of chronic obstructive pulmonary disease with deep learning on raw spirograms identifies new genetic loci and improves risk models J Cosentino, B Behsaz, B Alipanahi, ZR McCaw, D Hill, TH Schwantes-An, ... Nature Genetics 55 (5), 787-795, 2023 | 43 | 2023 |
Association of Nrf2 Polymorphism Haplotypes with Acute Lung Injury Phenotypes in Inbred Strains of Mice HY Cho, AE Jedlicka, W Gladwell, J Marzec, ZR McCaw, RJ Bienstock, ... Antioxidants & redox signaling 22 (4), 325-338, 2015 | 39 | 2015 |
DeepNull models non-linear covariate effects to improve phenotypic prediction and association power ZR McCaw, T Colthurst, T Yun, NA Furlotte, A Carroll, B Alipanahi, ... Nature communications 13 (1), 241, 2022 | 33 | 2022 |
Determinants of host susceptibility to murine respiratory syncytial virus (RSV) disease identify a role for the innate immunity scavenger receptor MARCO gene in human infants M High, HY Cho, J Marzec, T Wiltshire, KC Verhein, MT Caballero, ... EBioMedicine 11, 73-84, 2016 | 32 | 2016 |
Applying evidence-based medicine to shared decision making: value of the restricted mean survival time ZR McCaw, AR Orkaby, LJ Wei, DH Kim, MW Rich The American journal of medicine 132 (1), 13-15, 2019 | 31 | 2019 |
Practical recommendations on quantifying and interpreting treatment effects in the presence of terminal competing risks: a review ZR McCaw, BL Claggett, L Tian, SD Solomon, O Berwanger, MA Pfeffer, ... JAMA cardiology 7 (4), 450-456, 2022 | 29 | 2022 |
Novel roles for Notch3 and Notch4 receptors in gene expression and susceptibility to ozone-induced lung inflammation in mice KC Verhein, Z McCaw, W Gladwell, S Trivedi, PR Bushel, SR Kleeberger Environmental health perspectives 123 (8), 799-805, 2015 | 27 | 2015 |
Multitrait GWAS to connect disease variants and biological mechanisms H Julienne, V Laville, ZR McCaw, Z He, V Guillemot, C Lasry, A Ziyatdinov, ... PLoS genetics 17 (8), e1009713, 2021 | 25 | 2021 |
Analysis of response data for assessing treatment effects in comparative clinical studies B Huang, L Tian, ZR McCaw, X Luo, E Talukder, M Rothenberg, W Xie, ... Annals of internal medicine 173 (5), 368-374, 2020 | 25 | 2020 |
RNOmni: Rank normal transformation omnibus test Z McCaw R package 861, 2019 | 21 | 2019 |
Effects of mannose-binding lectin on pulmonary gene expression and innate immune inflammatory response to ozone JM Ciencewicki, KC Verhein, K Gerrish, ZR McCaw, J Li, PR Bushel, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (2 …, 2016 | 21 | 2016 |
Toll-like receptor 4-mediated respiratory syncytial virus disease and lung transcriptomics in differentially susceptible inbred mouse strains J Marzec, HY Cho, M High, ZR McCaw, F Polack, SR Kleeberger Physiological Genomics 51 (12), 630-643, 2019 | 19 | 2019 |