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Prasad Sulkshane
Prasad Sulkshane
Senior Research Scientist, o2h Discovery
Dirección de correo verificada de o2h.com
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Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia
P Sulkshane, J Ram, A Thakur, N Reis, O Kleifeld, MH Glickman
Redox biology 45, 102047, 2021
1242021
The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag
I Sahu, SM Mali, P Sulkshane, C Xu, A Rozenberg, R Morag, MP Sahoo, ...
Nature communications 12 (1), 6173, 2021
1102021
BH3 mimetic Obatoclax (GX15-070) mediates mitochondrial stress predominantly via MCL-1 inhibition and induces autophagy-dependent necroptosis in human oral cancer cells
P Sulkshane, T Teni
Oncotarget 8 (36), 60060, 2016
462016
Inhibition of proteasome reveals basal mitochondrial ubiquitination
P Sulkshane, I Duek, J Ram, A Thakur, N Reis, T Ziv, MH Glickman
Journal of Proteomics 229, 103949, 2020
362020
On-demand detachment of succinimides on cysteine to facilitate (semi) synthesis of challenging proteins
GB Vamisetti, G Satish, P Sulkshane, G Mann, MH Glickman, A Brik
Journal of the American Chemical Society 142 (46), 19558-19569, 2020
352020
Ubiquitination of intramitochondrial proteins: implications for metabolic adaptability
P Sulkshane, J Ram, MH Glickman
Biomolecules 10 (11), 1559, 2020
232020
Synthesis and delivery of a stable phosphorylated ubiquitin probe to study ubiquitin conjugation in mitophagy
M Guy, S Gandhesiri, S Prasad, M Shaswati, HG Michael, B Ashraf
Chemical Communications, 2021
21*2021
Elevated USP9X drives early-to-late-stage oral tumorigenesis via stabilisation of anti-apoptotic MCL-1 protein and impacts outcome in oral cancers
P Sulkshane, SN Pawar, R Waghole, SS Pawar, P Rajput, A Uthale, ...
British Journal of Cancer 125 (4), 547-560, 2021
152021
Myeloid cell leukemia-1: A formidable barrier to anticancer therapeutics and the quest of targeting it
P Sulkshane, T Teni
Exploration of Targeted Anti-tumor Therapy 3 (3), 278, 2022
122022
Signature activities of 20S proteasome include degradation of the ubiquitin-tag with the protein under hypoxia
I Sahu, SM Mali, P Sulkshane, A Rozenberg, C Xu, R Morag, MP Sahoo, ...
bioRxiv, 2019.12. 20.883942, 2019
112019
The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag. Nat. Commun. 12, 6173
I Sahu, SM Mali, P Sulkshane, C Xu, A Rozenberg, R Morag, MP Sahoo, ...
52021
Alzheimer's disease-associated mutant ubiquitin (UBB+ 1) is secreted through an autophagosome-like vesicle-mediated unconventional pathway
AR Wagh, P Sulakshane, MH Glickman
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1866 (2), 194936, 2023
42023
Identification of bicyclic compounds that act as dual inhibitors of bcl-2 and mcl-1
A Uthale, A Anantram, P Sulkshane, M Degani, T Teni
Molecular Diversity 27 (3), 1359-1374, 2023
32023
Comparative evaluation of the clonogenic capacity of periodontal ligament fibroblasts in Hank's balanced salt solution and egg albumen: An in vitro study
D Shah, P Sulkshane, R Lalwani, S Pawar, T Teni, A Kakade
Dental Traumatology 34 (4), 278-283, 2018
32018
Elevated translationally controlled tumour protein promotes oral cancer progression and poor outcome
D Sharma, SN Pawar, P Sulkshane, R Waghole, M Yasser, SS Pawar, ...
Journal of Oral Pathology & Medicine 52 (9), 849-859, 2023
12023
Invited Lectures
S Desai, A Barai, AB Bukhari, A De, S Sen
Journal of Radiation and Cancer Research 9 (1), 33-47, 2018
12018
Alzheimer's disease-associated mutant ubiquitin (UBB+1) is secreted through an autophagosome-like vesicle-mediated unconventional pathway
MHG Ajay R. Wagh, Prasad Sulakshane
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1866, 194936, 2023
2023
Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1
G Mann, P Sulkshane, P Sadhu, T Ziv, MH Glickman, A Brik
Molecules 27 (15), 4867, 2022
2022
Oncogenic role of TCTP in radioresistance and poor outcome in oral cancers
D Sharma, SN Pawar, P Sulkshane
Journal of Radiation and Cancer Research (Print) 13 (4), 180, 2022
2022
From ubiquitin-independent degradation to ubiquitin degradation-a signature activity of emergency 20S proteasome in hypoxia
I Sahu, SM Mali, P Sulkshane, R Morag, A Rosenberg, C Xu, MP Sahoo, ...
FEBS OPEN BIO 11, 16-17, 2021
2021
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