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Ming-ming Hu
Ming-ming Hu
武汉大学生命科学学院博士生
Dirección de correo verificada de whu.edu.cn
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TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination
J Zhang, MM Hu, YY Wang, HB Shu
Journal of Biological Chemistry 287 (34), 28646-28655, 2012
4012012
Sumoylation promotes the stability of the DNA sensor cGAS and the adaptor STING to regulate the kinetics of response to DNA virus
MM Hu, Q Yang, XQ Xie, CY Liao, H Lin, TT Liu, L Yin, HB Shu
Immunity 45 (3), 555-569, 2016
3372016
Human cytomegalovirus tegument protein UL82 inhibits STING-mediated signaling to evade antiviral immunity
YZ Fu, S Su, YQ Gao, PP Wang, ZF Huang, MM Hu, WW Luo, S Li, ...
Cell host & microbe 21 (2), 231-243, 2017
2092017
RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms
Y Qin, MT Zhou, MM Hu, YH Hu, J Zhang, L Guo, B Zhong, HB Shu
PLoS pathogens 10 (9), e1004358, 2014
2092014
TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination
J Yan, Q Li, AP Mao, MM Hu, HB Shu
Journal of molecular cell biology 6 (2), 154-163, 2014
2022014
Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5
MM Hu, CY Liao, Q Yang, XQ Xie, HB Shu
Journal of Experimental Medicine 214 (4), 973-989, 2017
1382017
TRIM38 inhibits TNFα-and IL-1β–triggered NF-κB activation by mediating lysosome-dependent degradation of TAB2/3
MM Hu, Q Yang, J Zhang, SM Liu, Y Zhang, H Lin, ZF Huang, YY Wang, ...
Proceedings of the National Academy of Sciences 111 (4), 1509-1514, 2014
1372014
The zinc-finger protein ZCCHC3 binds RNA and facilitates viral RNA sensing and activation of the RIG-I-like receptors
H Lian, R Zang, J Wei, W Ye, MM Hu, YD Chen, XN Zhang, Y Guo, CQ Lei, ...
Immunity 49 (3), 438-448. e5, 2018
1242018
ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response
H Lian, J Wei, R Zang, W Ye, Q Yang, XN Zhang, YD Chen, YZ Fu, MM Hu, ...
Nature communications 9 (1), 3349, 2018
1232018
TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses
Q Yang, TT Liu, H Lin, M Zhang, J Wei, WW Luo, YH Hu, B Zhong, MM Hu, ...
PLoS pathogens 13 (9), e1006600, 2017
1192017
Innate immune response to cytoplasmic DNA: mechanisms and diseases
MM Hu, HB Shu
Annual review of immunology 38 (1), 79-98, 2020
1162020
Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis
L Zhong, MM Hu, LJ Bian, Y Liu, Q Chen, HB Shu
Cell discovery 6 (1), 26, 2020
1132020
Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity
MM Hu, WR He, P Gao, Q Yang, K He, LB Cao, S Li, YQ Feng, HB Shu
Cell research 29 (3), 193-205, 2019
972019
Cytoplasmic mechanisms of recognition and defense of microbial nucleic acids
MM Hu, HB Shu
Annual review of cell and developmental biology 34 (1), 357-379, 2018
962018
TRIM38 negatively regulates TLR3/4-mediated innate immune and inflammatory responses by two sequential and distinct mechanisms
MM Hu, XQ Xie, Q Yang, CY Liao, W Ye, H Lin, HB Shu
The Journal of Immunology 195 (9), 4415-4425, 2015
932015
KAT5 acetylates cGAS to promote innate immune response to DNA virus
ZM Song, H Lin, XM Yi, W Guo, MM Hu, HB Shu
Proceedings of the National Academy of Sciences 117 (35), 21568-21575, 2020
812020
TRIM8 negatively regulates TLR3/4-mediated innate immune response by blocking TRIF–TBK1 interaction
W Ye, MM Hu, CQ Lei, Q Zhou, H Lin, MS Sun, HB Shu
The Journal of Immunology 199 (5), 1856-1864, 2017
812017
Multifaceted roles of TRIM38 in innate immune and inflammatory responses
MM Hu, HB Shu
Cellular & molecular immunology 14 (4), 331-338, 2017
782017
MARCH3 attenuates IL-1β–triggered inflammation by mediating K48-linked polyubiquitination and degradation of IL-1RI
H Lin, D Gao, MM Hu, M Zhang, XX Wu, L Feng, WH Xu, Q Yang, X Zhong, ...
Proceedings of the National Academy of Sciences 115 (49), 12483-12488, 2018
422018
PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation
BR Yan, L Zhou, MM Hu, M Li, H Lin, Y Yang, YY Wang, HB Shu
PLoS pathogens 13 (9), e1006648, 2017
392017
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Artículos 1–20