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| Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment Y Zhou, J Xu, Y Hou, JB Leverenz, A Kallianpur, R Mehra, Y Liu, H Yu, ... Alzheimer's research & therapy 13 (1), 110, 2021 | 146 | 2021 |
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| Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease J Fang, P Zhang, Q Wang, CW Chiang, Y Zhou, Y Hou, J Xu, R Chen, ... Alzheimer's research & therapy 14, 1-23, 2022 | 75 | 2022 |
| Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug … J Xu, P Zhang, Y Huang, Y Zhou, Y Hou, LM Bekris, J Lathia, CW Chiang, ... Genome research 31 (10), 1900-1912, 2021 | 71 | 2021 |
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| Synergy from gene expression and network mining (SynGeNet) method predicts synergistic drug combinations for diverse melanoma genomic subtypes KE Regan-Fendt, J Xu, M DiVincenzo, MC Duggan, R Shakya, R Na, ... NPJ systems biology and applications 5 (1), 6, 2019 | 53 | 2019 |
| Core signaling pathways in ovarian cancer stem cell revealed by integrative analysis of multi-marker genomics data T Zhang, J Xu, S Deng, F Zhou, J Li, L Zhang, L Li, QE Wang, F Li PLoS One 13 (5), e0196351, 2018 | 30 | 2018 |
| The Alzheimer's Cell Atlas (TACA): A single‐cell molecular map for translational therapeutics accelerator in Alzheimer's disease Y Zhou, J Xu, Y Hou, L Bekris, JB Leverenz, AA Pieper, J Cummings, ... Alzheimer's & Dementia: Translational Research & Clinical Interventions 8 (1 …, 2022 | 29 | 2022 |
| Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease C Gupta, J Xu, T Jin, S Khullar, X Liu, S Alatkar, F Cheng, D Wang PLoS Computational Biology 18 (7), e1010287, 2022 | 24 | 2022 |
| The effect of LKB1 activity on the sensitivity to PI3K/mTOR inhibition in non-small cell lung cancer T Shukuya, T Yamada, MJ Koenig, J Xu, T Okimoto, F Li, JM Amann, ... Journal of Thoracic Oncology, 2019 | 21 | 2019 |
| Pik3c3 deficiency in myeloid cells imparts partial resistance to experimental autoimmune encephalomyelitis associated with reduced IL-1β production G Yang, W Song, J Xu, JL Postoak, F Cheng, J Martinez, J Zhang, L Wu, ... Cellular & molecular immunology 18 (8), 2024-2039, 2021 | 17 | 2021 |
| Diffusion mapping of drug targets on disease signaling network elements reveals drug combination strategies J Xu, K Regan-Fendt, S Deng, WE Carson III, PRO Payne, F Li PACIFIC SYMPOSIUM ON BIOCOMPUTING 2018: Proceedings of the Pacific Symposium …, 2018 | 12 | 2018 |
| Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model GK Carling, L Fan, NR Foxe, K Norman, MY Wong, D Zhu, C Corona, ... Neuron 112 (23), 3877-3896. e8, 2024 | 9 | 2024 |
| Altered gene expression in excitatory neurons is associated with Alzheimer's disease and its higher incidence in women AX Garcia, J Xu, F Cheng, E Ruppin, AA Schäffer Alzheimer's & Dementia: Translational Research & Clinical Interventions 9 (1 …, 2023 | 9 | 2023 |
| Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer’s disease Y Qiu, Y Hou, D Gohel, Y Zhou, J Xu, M Bykova, Y Yang, JB Leverenz, ... Cell Reports 43 (5), 2024 | 7 | 2024 |
| Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment. Alzheimers Res Ther 13 (1): 110 Y Zhou, J Xu, Y Hou, JB Leverenz, A Kallianpur, R Mehra, Y Liu, H Yu, ... | 7 | 2021 |
| Identification of Parkinson’s disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data C Su, Y Hou, J Xu, Z Xu, M Zhou, A Ke, H Li, J Xu, M Brendel, ... npj Digital Medicine 7 (1), 184, 2024 | 5 | 2024 |
| Integrative analyses of multimodal clinical, neuroimaging, genetic, and transcriptomic data identify subtypes and potential treatments for heterogeneous Parkinson’s disease … C Su, Y Hou, J Xu, M Brendel, J Maasch, Z Bai, H Zhang, Y Zhu, ... | 5* | 2021 |
| Network medicine informed multiomics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis M Yu, J Xu, R Dutta, B Trapp, AA Pieper, F Cheng NPJ Systems Biology and Applications 10 (1), 128, 2024 | 2 | 2024 |