Targeting of porous hybrid silica nanoparticles to cancer cells JM Rosenholm, A Meinander, E Peuhu, R Niemi, JE Eriksson, C Sahlgren, ... ACS nano 3 (1), 197-206, 2009 | 603 | 2009 |
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1 CI Holmberg, V Hietakangas, A Mikhailov, JO Rantanen, M Kallio, ... The EMBO journal, 2001 | 431 | 2001 |
Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling A Meinander, C Runchel, T Tenev, L Chen, CH Kim, PS Ribeiro, ... The EMBO journal 31 (12), 2770-2783, 2012 | 132 | 2012 |
A simple mass-action model for the eukaryotic heat shock response and its mathematical validation I Petre, A Mizera, CL Hyder, A Meinander, A Mikhailov, RI Morimoto, ... Natural Computing 10, 595-612, 2011 | 82 | 2011 |
Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis SEF Tran, A Meinander, TH Holmström, A Rivero-Müller, KM Heiskanen, ... Cell Death & Differentiation 10 (10), 1137-1147, 2003 | 78 | 2003 |
M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila AL Aalto, AK Mohan, L Schwintzer, S Kupka, C Kietz, H Walczak, ... Cell Death & Differentiation 26 (5), 860-876, 2019 | 71 | 2019 |
PKC-mediated phosphorylation regulates c-FLIP ubiquitylation and stability A Kaunisto, V Kochin, T Asaoka, A Mikhailov, M Poukkula, A Meinander, ... Cell Death & Differentiation 16 (9), 1215-1226, 2009 | 70 | 2009 |
UBR5 is coamplified with MYC in breast tumors and encodes an ubiquitin ligase that limits MYC-dependent apoptosis X Qiao, Y Liu, ML Prada, AK Mohan, A Gupta, A Jaiswal, M Sharma, ... Cancer research 80 (7), 1414-1427, 2020 | 53 | 2020 |
An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival T Blom, N Bergelin, A Meinander, C Löf, JP Slotte, JE Eriksson, ... BMC cell biology 11, 1-11, 2010 | 52 | 2010 |
Type-2A protein phosphatase activity is required to maintain death receptor responsiveness AS Härmälä-Braskén, A Mikhailov, TS Söderström, A Meinander, ... Oncogene 22 (48), 7677-7686, 2003 | 52 | 2003 |
Instant decisions: transcription-independent control of death-receptor-mediated apoptosis SEF Tran, A Meinander, JE Eriksson Trends in biochemical sciences 29 (11), 601-608, 2004 | 46 | 2004 |
Tailored approaches in drug development and diagnostics: from molecular design to biological model systems C Sahlgren, A Meinander, H Zhang, F Cheng, M Preis, C Xu, TA Salminen, ... Advanced Healthcare Materials 6 (21), 1700258, 2017 | 43 | 2017 |
Generating Germ‐Free Drosophila to Study Gut‐Microbe Interactions: Protocol to Rear Drosophila Under Axenic Conditions C Kietz, V Pollari, A Meinander Current Protocols in Toxicology 77 (1), e52, 2018 | 37 | 2018 |
Fever-like hyperthermia controls T Lymphocyte persistence by inducing degradation of cellular FLIPshort A Meinander, TS Söderström, A Kaunisto, M Poukkula, L Sistonen, ... The Journal of Immunology 178 (6), 3944-3953, 2007 | 34 | 2007 |
Opposing roles for caspase and calpain death proteases in L-glutamate-induced oxidative neurotoxicity LM Elphick, M Hawat, NJ Toms, A Meinander, A Mikhailov, JE Eriksson, ... Toxicology and applied pharmacology 232 (2), 258-267, 2008 | 31 | 2008 |
Live cell detection of caspase-3 activation by a Discosoma-red-fluorescent-protein-based fluorescence resonance energy transfer construct LM Elphick, A Meinander, A Mikhailov, M Richard, NJ Toms, JE Eriksson, ... Analytical biochemistry 349 (1), 148-155, 2006 | 23 | 2006 |
Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis HT Toivonen, A Meinander, T Asaoka, M Westerlund, F Pettersson, ... Journal of Biological Chemistry 286 (21), 18375-18382, 2011 | 17 | 2011 |
Lamin A/C phosphorylation at serine 22 is a conserved heat shock response to regulate nuclear adaptation during stress L Virtanen, E Holm, M Halme, G West, F Lindholm, J Gullmets, J Irjala, ... Journal of Cell Science 136 (4), jcs259788, 2023 | 13 | 2023 |
M1‐linked ubiquitination facilitates NF‐κB activation and survival during sterile inflammation A Aalto, G Martínez‐Chacón, C Kietz, N Tsyganova, J Kreutzer, P Kallio, ... The FEBS Journal 289 (17), 5180-5197, 2022 | 12 | 2022 |
Drice restrains Diap2-mediated inflammatory signalling and intestinal inflammation C Kietz, AK Mohan, V Pollari, IE Tuominen, PS Ribeiro, P Meier, ... Cell Death & Differentiation 29 (1), 28-39, 2022 | 12 | 2022 |