Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G NJ Moerke, H Aktas, H Chen, S Cantel, MY Reibarkh, A Fahmy, JD Gross, ... Cell 128 (2), 257-267, 2007 | 667 | 2007 |
Small molecule inhibition of phosphatidylinositol-3, 4, 5-triphosphate (PIP3) binding to pleckstrin homology domains B Miao, I Skidan, J Yang, A Lugovskoy, M Reibarkh, K Long, T Brazell, ... Proceedings of the National Academy of Sciences 107 (46), 20126-20131, 2010 | 170 | 2010 |
A multifunctional catalyst that stereoselectively assembles prodrugs DA DiRocco, Y Ji, EC Sherer, A Klapars, M Reibarkh, J Dropinski, ... Science 356 (6336), 426-430, 2017 | 163 | 2017 |
Selective pharmacological targeting of a DEAD box RNA helicase L Lindqvist, M Oberer, M Reibarkh, R Cencic, ME Bordeleau, E Vogt, ... PloS one 3 (2), e1583, 2008 | 157 | 2008 |
Oxyfunctionalization of the remote C− H bonds of aliphatic amines by decatungstate photocatalysis DM Schultz, F Lévesque, DA DiRocco, M Reibarkh, Y Ji, LA Joyce, ... Angewandte Chemie International Edition 56 (48), 15274-15278, 2017 | 138 | 2017 |
The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β RE Luna, H Arthanari, H Hiraishi, J Nanda, P Martin-Marcos, MA Markus, ... Cell reports 1 (6), 689-702, 2012 | 84 | 2012 |
LED‐Illuminated NMR spectroscopy: a practical tool for mechanistic studies of photochemical reactions Y Ji, DA DiRocco, J Kind, CM Thiele, RM Gschwind, M Reibarkh ChemPhotoChem 3 (10), 984-992, 2019 | 83 | 2019 |
Facile quantum yield determination via NMR actinometry Y Ji, DA DiRocco, CM Hong, MK Wismer, M Reibarkh Organic letters 20 (8), 2156-2159, 2018 | 82 | 2018 |
Chaotropic effects in sub/supercritical fluid chromatography via ammonium hydroxide in water-rich modifiers: enabling separation of peptides and highly polar pharmaceuticals at … J Liu, AA Makarov, R Bennett, IA Haidar Ahmad, J DaSilva, M Reibarkh, ... Analytical chemistry 91 (21), 13907-13915, 2019 | 74 | 2019 |
Eukaryotic initiation factor (eIF) 1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection M Reibarkh, Y Yamamoto, CR Singh, F Del Rio, A Fahmy, B Lee, ... Journal of Biological Chemistry 283 (2), 1094-1103, 2008 | 73 | 2008 |
Manufacturing process development for belzutifan, part 2: a continuous flow visible-light-induced benzylic bromination C Bottecchia, F Levesque, JP McMullen, Y Ji, M Reibarkh, F Peng, L Tan, ... Organic Process Research & Development 26 (3), 516-524, 2021 | 65 | 2021 |
Interatomic potentials and solvation parameters from protein engineering data for buried residues AL Lomize, MY Reibarkh, ID Pogozheva Protein science 11 (8), 1984-2000, 2002 | 54 | 2002 |
pKa measurements for the SAMPL6 prediction challenge for a set of kinase inhibitor-like fragments M Işık, D Levorse, AS Rustenburg, IE Ndukwe, H Wang, X Wang, ... Journal of computer-aided molecular design 32, 1117-1138, 2018 | 53 | 2018 |
Discovery of novel indoline cholesterol ester transfer protein inhibitors (CETP) through a structure-guided approach JE Wilson, R Kurukulasuriya, M Reibarkh, M Reiter, A Zwicker, K Zhao, ... ACS Medicinal Chemistry Letters 7 (3), 261-265, 2016 | 48 | 2016 |
Discovery of N-[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible … JS Debenham, C Madsen-Duggan, MJ Clements, TF Walsh, JT Kuethe, ... Journal of medicinal chemistry 59 (24), 11039-11049, 2016 | 47 | 2016 |
Secondary amine selective Petasis (SASP) bioconjugation YE Sim, O Nwajiobi, S Mahesh, RD Cohen, MY Reibarkh, M Raj Chemical Science 11 (1), 53-61, 2020 | 45 | 2020 |
Discovery of a Photoinduced Dark Catalytic Cycle Using in Situ LED-NMR Spectroscopy D Lehnherr, Y Ji, AJ Neel, RD Cohen, APJ Brunskill, J Yang, M Reibarkh Journal of the American Chemical Society 140 (42), 13843-13853, 2018 | 44 | 2018 |
Kilo-Scale Electrochemical Oxidation of a Thioether to a Sulfone: A Workflow for Scaling up Electrosynthesis C Bottecchia, D Lehnherr, F Lévesque, M Reibarkh, Y Ji, VL Rodrigues, ... Organic Process Research & Development 26 (8), 2423-2437, 2022 | 40 | 2022 |
Complex macrocycle exploration: parallel, heuristic, and constraint-based conformer generation using ForceGen AN Jain, AE Cleves, Q Gao, X Wang, Y Liu, EC Sherer, MY Reibarkh Journal of computer-aided molecular design 33, 531-558, 2019 | 40 | 2019 |
NMR distinction of single-and multiple-mode binding of small-molecule protein ligands M Reibarkh, TJ Malia, G Wagner Journal of the American Chemical Society 128 (7), 2160-2161, 2006 | 40 | 2006 |