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Migle Kazlauskiene
Migle Kazlauskiene
Faculty of Medicine, Vilnius University
Dirección de correo verificada de mf.vu.lt
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A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems
M Kazlauskiene, G Kostiuk, Č Venclovas, G Tamulaitis, V Siksnys
Science 357 (6351), 605-609, 2017
4752017
Programmable RNA shredding by the type III-A CRISPR-Cas system of Streptococcus thermophilus
G Tamulaitis, M Kazlauskiene, E Manakova, Č Venclovas, AO Nwokeoji, ...
Molecular cell 56 (4), 506-517, 2014
3452014
Spatiotemporal control of type III-A CRISPR-Cas immunity: coupling DNA degradation with the target RNA recognition
M Kazlauskiene, G Tamulaitis, G Kostiuk, Č Venclovas, V Siksnys
Molecular cell 62 (2), 295-306, 2016
2892016
Binding affinity in drug design: experimental and computational techniques
V Kairys, L Baranauskiene, M Kazlauskiene, D Matulis, E Kazlauskas
Expert opinion on drug discovery 14 (8), 755-768, 2019
1562019
Hakai is required for stabilization of core components of the m6A mRNA methylation machinery
P Bawankar, T Lence, C Paolantoni, IU Haussmann, M Kazlauskiene, ...
Nature communications 12 (1), 3778, 2021
1302021
Type III-A CRISPR-associated protein Csm6 degrades cyclic hexa-adenylate activator using both CARF and HEPN domains
D Smalakyte, M Kazlauskiene, J F. Havelund, A Rukšėnaitė, A Rimaite, ...
Nucleic Acids Research 48 (16), 9204-9217, 2020
442020
Genetic dissection of the type III-A CRISPR-Cas system csm complex reveals roles of individual subunits
I Mogila, M Kazlauskiene, S Valinskyte, G Tamulaitiene, G Tamulaitis, ...
Cell reports 26 (10), 2753-2765. e4, 2019
342019
Targeted RNA knockdown and knockout by type III-A Csm complexes
T Fricke, M Bochtler, G Tamulaitis, M Kazlauskiene
US Patent 11,274,317, 2022
52022
Recent advances in computational and experimental protein-ligand affinity determination techniques
V Kairys, L Baranauskiene, M Kazlauskiene, A Zubrienė, V Petrauskas, ...
Expert Opinion on Drug Discovery 19 (6), 649-670, 2024
32024
Production of cyclic adenylates and their use as allosteric regulators
V Siksnys, M Kazlauskiene, G Kostiuk, G Tamulaitis
US Patent App. 16/618,238, 2021
22021
Programmable RNA shredding by the type III-A CRISPR-Cas system of Streptococcus thermophilus
V Siksnys, M Kazlauskiene, G Tamulaitis
US Patent 10,385,336, 2019
22019
Regulation of CRISPR-associated rossman fold (CARF) domain containing proteins by oligoadenylates
V Šikšnys, M Kazlauskiene, G Kostiuk, G Tamulaitis
US Patent 12,123,031, 2024
2024
Characterization of Streptococcus thermophilus Csm complex mediated CRISPR interference in vitro
G Tamulaitis, M Kazlauskiene, E Manakova, C Venclovas, AO Nwokeoji, ...
FEBS JOURNAL 281, 678-678, 2014
2014
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