| Thousands of chemical starting points for antimalarial lead identification FJ Gamo, LM Sanz, J Vidal, C De Cozar, E Alvarez, JL Lavandera, ... Nature 465 (7296), 305-310, 2010 | 1183 | 2010 |
| A novel multiple-stage antimalarial agent that inhibits protein synthesis B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ... Nature 522 (7556), 315-320, 2015 | 486 | 2015 |
| Fueling open‐source drug discovery: 177 small‐molecule leads against tuberculosis L Ballell, RH Bates, RJ Young, D Alvarez‐Gomez, E Alvarez‐Ruiz, ... ChemMedChem 8 (2), 313-321, 2013 | 373 | 2013 |
| A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria MA Phillips, J Lotharius, K Marsh, J White, A Dayan, KL White, ... Science translational medicine 7 (296), 296ra111-296ra111, 2015 | 355 | 2015 |
| Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors … JM Coteron, M Marco, J Esquivias, X Deng, KL White, J White, M Koltun, ... Journal of medicinal chemistry 54 (15), 5540-5561, 2011 | 337 | 2011 |
| Global Transcriptional Response of Bacillus subtilis to Heat Shock JD Helmann, MFW Wu, PA Kobel, FJ Gamo, M Wilson, MM Morshedi, ... Journal of Bacteriology 183 (24), 7318-7328, 2001 | 329 | 2001 |
| Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 316 | 2016 |
| (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ... Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014 | 291 | 2014 |
| Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase T Paquet, C Le Manach, DG Cabrera, Y Younis, PP Henrich, TS Abraham, ... Science translational medicine 9 (387), eaad9735, 2017 | 273 | 2017 |
| Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ... Science 359 (6372), 191-199, 2018 | 256 | 2018 |
| Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 256 | 2013 |
| P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action LM Sanz, B Crespo, C De-Cozar, XC Ding, JL Llergo, JN Burrows, ... PloS one 7 (2), e30949, 2012 | 242 | 2012 |
| Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity A Cameron, J Read, R Tranter, VJ Winter, RB Sessions, RL Brady, ... Journal of Biological Chemistry 279 (30), 31429-31439, 2004 | 188 | 2004 |
| Global phenotypic screening for antimalarials WA Guiguemde, AA Shelat, JF Garcia-Bustos, TT Diagana, FJ Gamo, ... Chemistry & biology 19 (1), 116-129, 2012 | 174 | 2012 |
| Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum AB Vaidya, JM Morrisey, Z Zhang, S Das, TM Daly, TD Otto, NJ Spillman, ... Nature communications 5 (1), 5521, 2014 | 167 | 2014 |
| A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission DA Baker, LB Stewart, JM Large, PW Bowyer, KH Ansell, ... Nature communications 8 (1), 430, 2017 | 142 | 2017 |
| Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug FP da Cruz, C Martin, K Buchholz, MJ Lafuente-Monasterio, T Rodrigues, ... Journal of Infectious Diseases 205 (8), 1278-1286, 2012 | 138 | 2012 |
| A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue E Sonoiki, CL Ng, MCS Lee, D Guo, YK Zhang, Y Zhou, MRK Alley, ... Nature communications 8 (1), 14574, 2017 | 137 | 2017 |
| A broad analysis of resistance development in the malaria parasite VC Corey, AK Lukens, ES Istvan, MCS Lee, V Franco, P Magistrado, ... Nature communications 7 (1), 11901, 2016 | 133 | 2016 |
| Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis B Baragaña, B Forte, R Choi, S Nakazawa Hewitt, JA Bueren-Calabuig, ... Proceedings of the National Academy of Sciences 116 (14), 7015-7020, 2019 | 127 | 2019 |
Antonio CasamayorDept. Bioquímica i Biol. Molecular. Universitat Autònoma de BarcelonaDirección de correo verificada de uab.es
