Phase separation mediates NUP98 fusion oncoprotein leukemic transformation B Chandra, NL Michmerhuizen, HK Shirnekhi, S Tripathi, BJ Pioso, ... Cancer discovery 12 (4), 1152-1169, 2022 | 103 | 2022 |
Defining the condensate landscape of fusion oncoproteins S Tripathi, HK Shirnekhi, SD Gorman, B Chandra, DW Baggett, CG Park, ... Nature communications 14 (1), 6008, 2023 | 27 | 2023 |
Hyper-active RAS/MAPK introduces cancer-specific mitotic vulnerabilities JA Herman, RR Romain, P Hoellerbauer, HK Shirnekhi, DC King, ... Proceedings of the National Academy of Sciences 119 (41), e2208255119, 2022 | 17 | 2022 |
The role of phase-separated condensates in fusion oncoprotein–driven cancers HK Shirnekhi, B Chandra, RW Kriwacki Annual Review of Cancer Biology 7 (1), 73-91, 2023 | 15 | 2023 |
An image analysis pipeline for quantifying the features of fluorescently-labeled biomolecular condensates in cells DW Baggett, A Medyukhina, S Tripathi, HK Shirnekhi, H Wu, SB Pounds, ... Frontiers in Bioinformatics 2, 897238, 2022 | 12 | 2022 |
Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation HK Shirnekhi, EP Kelley, JG DeLuca, JA Herman Molecular biology of the cell 28 (15), 2035-2041, 2017 | 12 | 2017 |
BuGZ facilitates loading of spindle assembly checkpoint proteins to kinetochores in early mitosis HK Shirnekhi, JA Herman, PJ Paddison, JG DeLuca Journal of Biological Chemistry 295 (43), 14666-14677, 2020 | 7 | 2020 |
Phase separation mediates NUP98 fusion oncoprotein leukemic transformation. Cancer Discov. 2022; 12: 1152–1169. doi: 10.1158/2159-8290 B Chandra, NL Michmerhuizen, HK Shirnekhi, S Tripathi, BJ Pioso, ... CD-21-0674.[Europe PMC free article][Abstract][CrossRef][Academic Search], 0 | 5 | |
Dissolving Fusion Oncoprotein Condensates to Reverse Aberrant Gene Expression HK Shirnekhi, B Chandra, RW Kriwacki Cancer Research 83 (20), 3324-3326, 2023 | 1 | 2023 |
AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation N Michmerhuizen, B Chandra, H Shirnekhi, S Tripathi, B Pioso, D Baggett, ... Clinical Lymphoma Myeloma and Leukemia 22, S220, 2022 | 1 | 2022 |
Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia Q Jin, E Harris, JA Myers, R Mehmood, A Cotton, HK Shirnekhi, ... Blood 144 (23), 2417-2431, 2024 | | 2024 |
EPEN-22. ZFTA FUSION ONCOPROTEINS DRIVE ONCOGENESIS THROUGH ASSEMBLY OF BIOMOLECULAR CONDENSATES S Varadharajan, A Arabzade, HK Shirnekhi, S Ippagunta, N Laboe, D Gee, ... Neuro-Oncology 26 (Suppl 4), 0, 2024 | | 2024 |
ZFTA fusion oncoproteins drive tumorigenesis through transcriptional condensates A Arabzade, H Shirnekhi, S Varadharajan, S Ippagunta, N Laboe, D Gee, ... | | 2024 |
Understanding condensate formation by fusion oncoprotein-derived intrinsically disordered regions S Kinger, BJ Pioso, S Tripathi, AH Phillips, CG Park, S Maiti, SD Gorman, ... Biophysical Journal 122 (3), 345a, 2023 | | 2023 |
Defining the condensate landscape of fusion oncoproteins DW Baggett, H Shirnekhi, B Chandra, S Tripathi, BJ Pioso, R Kriwacki Biophysical Journal 122 (3), 486a, 2023 | | 2023 |
Phase separation underlies interactions of the SARS-CoV-2 nucleocapsid protein with nucleoli P Dogra, H Shirnekhi, MC Ferrolino, M Tolbert, CG Park, RW Kriwacki Biophysical Journal 122 (3), 205a, 2023 | | 2023 |
Poster: AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation N Michmerhuizen, B Chandra, H Shirnekhi, S Tripathi, B Pioso, D Baggett, ... Clinical Lymphoma, Myeloma and Leukemia 22, S129, 2022 | | 2022 |
The role of phase separation by NUP98 fusion oncoproteins in leukemia B Chandra, N Michmerhuizen, H Shirnekhi, S Tripathi, B Pioso, ... Biophysical Journal 121 (3), 357a, 2022 | | 2022 |
Understanding the mechanism of TCF3-HLF fusion oncoprotein-driven leukemogenesis HK Shirnekhi, SD Gorman, NL Michmerhuizen, S Tripathi, A Medyukhina, ... Biophysical Journal 121 (3), 356a, 2022 | | 2022 |
Are fusion oncoproteins a source of disease-relevant, phase separation-prone protein regions? SD Gorman, H Shirnekhi, R Somjee, S Tripathi, CG Park, AH Phillips, ... Biophysical Journal 121 (3), 307a, 2022 | | 2022 |