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George J Mulligan
George J Mulligan
Multiple Myeloma Research Foundation
Dirección de correo verificada de themmrf.org
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Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma
JJ Keats, R Fonseca, M Chesi, R Schop, A Baker, WJ Chng, S Van Wier, ...
Cancer cell 12 (2), 131-144, 2007
12512007
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
L Shi, G Campbell, WD Jones, F Campagne, Z Wen, SJ Walker, Z Su, ...
Nature biotechnology 28 (8), 827-838, 2010
8922010
SR proteins and splicing control 1569
JL Manley, R Tacke, BLM Hogan, KL Friedman, JD Diller, BM Ferguson, ...
Genes Dev 10, 1569-1579, 1996
8741996
A subset of p53-deficient embryos exhibit exencephaly
VP Sah, LD Attardi, GJ Mulligan, BO Williams, RT Bronson, T Jacks
Nature genetics 10 (2), 175-180, 1995
7331995
Targeted disruption of the three Rb-related genes leads to loss of G1 control and immortalization
J Sage, GJ Mulligan, LD Attardi, A Miller, SQ Chen, B Williams, ...
Genes & development 14 (23), 3037-3050, 2000
7262000
Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma
S Kumar, I Flinn, PG Richardson, P Hari, N Callander, SJ Noga, ...
Blood, The Journal of the American Society of Hematology 119 (19), 4375-4382, 2012
5832012
Shared role of the pRB-related p130 and p107 proteins in limb development.
D Cobrinik, MH Lee, G Hannon, G Mulligan, RT Bronson, N Dyson, ...
Genes & development 10 (13), 1633-1644, 1996
5651996
Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
G Mulligan, C Mitsiades, B Bryant, F Zhan, WJ Chng, S Roels, E Koenig, ...
Blood 109 (8), 3177-3188, 2007
4782007
Targeted disruption of p107: functional overlap between p107 and Rb.
MH Lee, BO Williams, G Mulligan, S Mukai, RT Bronson, N Dyson, ...
Genes & development 10 (13), 1621-1632, 1996
4601996
The retinoblastoma gene family: cousins with overlapping interests
G Mulligan, T Jacks
Trends in Genetics 14 (6), 223-229, 1998
4241998
Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle.
BG Novitch, GJ Mulligan, T Jacks, AB Lassar
The Journal of cell biology 135 (2), 441-456, 1996
3811996
Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients
A Broyl, D Hose, H Lokhorst, Y de Knegt, J Peeters, A Jauch, U Bertsch, ...
Blood, The Journal of the American Society of Hematology 116 (14), 2543-2553, 2010
3772010
Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma
WJ Chng, GF Huang, TH Chung, SB Ng, N Gonzalez-Paz, T Troska-Price, ...
Leukemia 25 (6), 1026-1035, 2011
3292011
Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling
WJ Chng, S Kumar, S VanWier, G Ahmann, T Price-Troska, K Henderson, ...
Cancer research 67 (7), 2982-2989, 2007
3262007
A gene expression signature for high-risk multiple myeloma
R Kuiper, A Broyl, Y de Knegt, MH Van Vliet, EH Van Beers, ...
Leukemia 26 (11), 2406-2413, 2012
3032012
Phase I study of the novel investigational NEDD8-activating enzyme inhibitor pevonedistat (MLN4924) in patients with relapsed/refractory multiple myeloma or lymphoma
JJ Shah, AJ Jakubowiak, OA O'Connor, RZ Orlowski, RD Harvey, ...
Clinical Cancer Research 22 (1), 34-43, 2016
1932016
Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA.
GJ Mulligan, W Guo, S Wormsley, DM Helfman
Journal of Biological Chemistry 267 (35), 25480-25487, 1992
1921992
Randomized phase II study of R-CHOP with or without bortezomib in previously untreated patients with non–germinal center B-cell–like diffuse large B-cell lymphoma
JP Leonard, KS Kolibaba, JA Reeves, A Tulpule, IW Flinn, T Kolevska, ...
Journal of Clinical Oncology 35 (31), 3538-3546, 2017
1892017
Phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with advanced solid tumors
J Sarantopoulos, GI Shapiro, RB Cohen, JW Clark, JS Kauh, GJ Weiss, ...
Clinical Cancer Research 22 (4), 847-857, 2016
1802016
The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition
WJ Chng, E Braggio, G Mulligan, B Bryant, E Remstein, R Valdez, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1603-1609, 2008
1472008
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