Programmed DNA destruction by miniature CRISPR-Cas14 enzymes LB Harrington, D Burstein, JS Chen, D Paez-Espino, E Ma, IP Witte, ... Science 362 (6416), 839-842, 2018 | 1075 | 2018 |
Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors JR Davis, X Wang, IP Witte, TP Huang, JM Levy, A Raguram, S Banskota, ... Nature Biomedical Engineering 6 (11), 1272-1283, 2022 | 125 | 2022 |
CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks JC Cofsky, D Karandur, CJ Huang, IP Witte, J Kuriyan, JA Doudna Elife 9, e55143, 2020 | 94 | 2020 |
A scoutRNA is required for some type V CRISPR-Cas systems LB Harrington, E Ma, JS Chen, IP Witte, D Gertz, D Paez-Espino, ... Molecular cell 79 (3), 416-424. e5, 2020 | 71 | 2020 |
Site-specific lipidation enhances IFITM3 membrane interactions and antiviral activity EH Garst, H Lee, T Das, S Bhattacharya, A Percher, R Wiewiora, IP Witte, ... ACS chemical biology 16 (5), 844-856, 2021 | 29 | 2021 |
Programmable nuclease improvements and compositions and methods for nucleic acid amplification and detection LB Harrington, JS Chen, JP Broughton, PPD Galarza, WJ Hartono, ... US Patent 11,174,470, 2021 | 18 | 2021 |
Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors. Nat Biomed Eng. 2022; 6: 1272–1283 JR Davis, X Wang, IP Witte, TP Huang, JM Levy, A Raguram | 5 | |
Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors (Jul, 10.1038/s41551-022-00911-4, 2022) JR Davis, X Wang, IP Witte, TP Huang, JM Levy, A Raguram, S Banskota, ... Nature Biomedical Engineering 6 (11), 1317-1317, 2022 | 2 | 2022 |
Publisher Correction: Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors JR Davis, X Wang, IP Witte, TP Huang, JM Levy, A Raguram, S Banskota, ... Nature Biomedical Engineering 6 (11), 1317, 2022 | 2 | 2022 |
Programmable nucleases and methods of use LB Harrington, JS Chen, IP Witte US Patent App. 17/516,027, 2022 | 1 | 2022 |
PROGRAMMABLE NUCLEASES AND METHODS OF USE LB Harrington, JS Chen, IP Witte US Patent App. 18/584,462, 2024 | | 2024 |
COMPOSITIONS AND METHODS FOR DETECTING MODIFIED NUCLEIC ACIDS AND AMPLIFYING ssDNA LB Harrington, JS Chen, JP Broughton, IP Witte US Patent App. 17/365,967, 2022 | | 2022 |
Programmable nuclease improvements and compositions and methods for nucleic acid amplification and detection LB Harrington, JS Chen, JP Broughton, PPD Galarza, WJ Hartono, ... US Patent App. 17/495,652, 2022 | | 2022 |