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Rebecca J. Thrush
Rebecca J. Thrush
Research Associate, Imperial College London
Dirección de correo verificada de ic.ac.uk
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N-terminal acetylation of α-synuclein slows down its aggregation process and alters the morphology of the resulting aggregates
R Bell, RJ Thrush, M Castellana-Cruz, M Oeller, R Staats, A Nene, ...
Biochemistry 61 (17), 1743-1756, 2022
372022
Effects of N-terminal acetylation on the aggregation of disease-related α-synuclein variants
R Bell, M Castellana-Cruz, A Nene, RJ Thrush, CK Xu, JR Kumita, ...
Journal of Molecular Biology 435 (1), 167825, 2023
322023
α-Synuclein aggregation is triggered by oligomeric amyloid-β 42 via heterogeneous primary nucleation
DM Vadukul, M Papp, RJ Thrush, J Wang, Y Jin, P Arosio, FA Aprile
Journal of the American Chemical Society 145 (33), 18276-18285, 2023
132023
The diagnostic potential of amyloidogenic proteins
Y Jin, DM Vadukul, D Gialama, Y Ge, R Thrush, JT White, FA Aprile
International Journal of Molecular Sciences 22 (8), 4128, 2021
82021
A facile method to produce N-terminally truncated α-synuclein
RJ Thrush, DM Vadukul, FA Aprile
Frontiers in Neuroscience 16, 881480, 2022
42022
BPS2025-Understanding protein self-assembly using an integrative antibody-discovery approach
DM Vadukul, D Gialama, Y Ge, RJ Thrush, G Corucci, SE Radford, ...
Biophysical Journal 124 (3), 511a, 2025
2025
The N-terminal Region of α-Synuclein Controls Amyloid Nucleation at the Condensate Interface
RJ Thrush, DM Vadukul, SC Allerton, M Storch, FA Aprile
bioRxiv, 2024.06. 06.597302, 2024
2024
A Potent Sybody Selectively Inhibits α-Synuclein Amyloid Formation by Binding to the P1 Region
D Gialama, DM Vadukul, RJ Thrush, SE Radford, FA Aprile
Journal of Medicinal Chemistry 67 (12), 9857-9868, 2024
2024
α-Synuclein Aggregation is Triggered by Amyloid-β Oligomers via Heterogeneous Primary Nucleation
DM Vadukul, M Papp, RJ Thrush, J Wang, Y Jin, P Arosio, FA Aprile
2022
Amyloid-β Oligomers Serve as Nucleation Sites for α-Synuclein Aggregation
DM Vadukul, RJ Thrush, Y Jin, FA Aprile
bioRxiv, 2022.06. 20.496547, 2022
2022
Effects of N-Terminal Acetylation on the Aggregationof Disease-Related a Lpha-Synuclein Variants
M Vendruscolo, M Castellana-Cruz, A Nene, RJ Thrush, CK Xu, ...
Available at SSRN 4194537, 0
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