| Discovery of IDO1 inhibitors: from bench to bedside GC Prendergast, WP Malachowski, JB DuHadaway, AJ Muller Cancer research 77 (24), 6795-6811, 2017 | 552 | 2017 |
| Indoleamine 2, 3-dioxygenase and its therapeutic inhibition in cancer GC Prendergast, WJ Malachowski, A Mondal, P Scherle, AJ Muller International review of cell and molecular biology 336, 175-203, 2018 | 273 | 2018 |
| Structure− activity study of brassinin derivatives as indoleamine 2, 3-dioxygenase inhibitors P Gaspari, T Banerjee, WP Malachowski, AJ Muller, GC Prendergast, ... Journal of medicinal chemistry 49 (2), 684-692, 2006 | 237 | 2006 |
| Indoleamine 2, 3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors S Kumar, WP Malachowski, JB DuHadaway, JM LaLonde, PJ Carroll, ... Journal of medicinal chemistry 51 (6), 1706-1718, 2008 | 212 | 2008 |
| A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2, 3-dioxygenase T Banerjee, JB Duhadaway, P Gaspari, E Sutanto-Ward, DH Munn, ... Oncogene 27 (20), 2851-2857, 2008 | 207 | 2008 |
| Structure based development of phenylimidazole-derived inhibitors of indoleamine 2, 3-dioxygenase S Kumar, D Jaller, B Patel, JM LaLonde, JB DuHadaway, ... Journal of medicinal chemistry 51 (16), 4968-4977, 2008 | 201 | 2008 |
| Indoleamine 2, 3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors AJ Muller, WP Malachowski, GC Prendergast Expert opinion on therapeutic targets 9 (4), 831-849, 2005 | 148 | 2005 |
| The chemistry of phosphapeptides: Formation of functionalized phosphonochloridates under mild conditions and their reaction with alcohols and amines WP Malachowski, JK Coward The Journal of Organic Chemistry 59 (25), 7616-7624, 1994 | 125 | 1994 |
| Methods for the treatment of cancer GC Prendergast, AJ Muller, JB Duhadaway, W Malachowski US Patent 8,008,281, 2011 | 109 | 2011 |
| Nature of the rate-determining steps of the reaction catalyzed by the Yersinia protein-tyrosine phosphatase. ZY Zhang, WP Malachowski, RL Van Etten, JE Dixon Journal of Biological Chemistry 269 (11), 8140-8145, 1994 | 109 | 1994 |
| The chemistry of phosphapeptides: investigations on the synthesis of phosphonamidate, phosphonate, and phosphinate analogs of glutamyl-. gamma.-glutamate WP Malachowski, JK Coward The Journal of Organic Chemistry 59 (25), 7625-7634, 1994 | 107 | 1994 |
| Asymmetric total synthesis of (+)-apovincamine and a formal synthesis of (+)-vincamine. Demonstration of a practical “asymmetric linkage” between aromatic carboxylic acids and … AG Schultz, WP Malachowski, Y Pan The Journal of Organic Chemistry 62 (5), 1223-1229, 1997 | 55 | 1997 |
| The Enantioselective synthesis of (−)-lycoramine with the birch− cope sequence WP Malachowski, T Paul, S Phounsavath The Journal of Organic Chemistry 72 (18), 6792-6796, 2007 | 50 | 2007 |
| The Enantioselective Birch− Cope Sequence for the Synthesis of Carbocyclic Quaternary Stereocenters. Application to the Synthesis of (+)-Mesembrine T Paul, WP Malachowski, J Lee Organic Letters 8 (18), 4007-4010, 2006 | 50 | 2006 |
| Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2, 3-dioxygenase-1, indoleamine 2, 3-dioxygenase-2 and tryptophan dioxygenase M Winters, JB DuHadaway, KN Pham, A Lewis-Ballester, S Badir, J Wai, ... European journal of medicinal chemistry 162, 455-464, 2019 | 47 | 2019 |
| O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2, 3-dioxygenase-1 WP Malachowski, M Winters, JB DuHadaway, A Lewis-Ballester, S Badir, ... European journal of medicinal chemistry 108, 564-576, 2016 | 44 | 2016 |
| The tumor-selective cytotoxic agent β-lapachone is a potent inhibitor of IDO1 HE Flick, JM LaLonde, WP Malachowski, AJ Muller International Journal of Tryptophan Research 6, IJTR. S12094, 2013 | 41 | 2013 |
| The synthesis of azapeptidomimetic β-lactam molecules as potential protease inhibitors WP Malachowski, C Tie, K Wang, RL Broadrup The Journal of Organic Chemistry 67 (25), 8962-8969, 2002 | 41 | 2002 |
| IDO inhibitors and methods of use GC Prendergast, AJ Muller, JB DuHadaway, W Malachowski US Patent 7,714,139, 2010 | 39 | 2010 |
| IDO inhibitors MR Mautino, S Kumar, F Jaipuri, J Waldo, T Kesharwani, NN Vahanian, ... US Patent 8,748,469, 2014 | 35 | 2014 |
