The antibiotic resistome: a guide for the discovery of natural products as antimicrobial agents C Hobson, AN Chan, GD Wright Chemical Reviews 121 (6), 3464-3494, 2021 | 181 | 2021 |
An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles ‘fungal’icosalide antibiotics M Jenner, X Jian, Y Dashti, J Masschelein, C Hobson, DM Roberts, ... Chemical science 10 (21), 5489-5494, 2019 | 45 | 2019 |
A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis J Masschelein, PK Sydor, C Hobson, R Howe, C Jones, DM Roberts, ... Nature chemistry 11 (10), 906-912, 2019 | 38 | 2019 |
ClpP inhibitors are produced by a widespread family of bacterial gene clusters EJ Culp, D Sychantha, C Hobson, AC Pawlowski, G Prehna, GD Wright Nature Microbiology 7 (3), 451-462, 2022 | 30 | 2022 |
NMR-based assignment of isoleucine vs. allo-isoleucine stereochemistry ZJ Anderson, C Hobson, R Needley, L Song, MS Perryman, P Kerby, ... Organic & Biomolecular Chemistry 15 (44), 9372-9378, 2017 | 13 | 2017 |
Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory MA Cook, D Pallant, L Ejim, AD Sutherland, X Wang, JW Johnson, ... Journal of Industrial Microbiology and Biotechnology 50 (1), kuad042, 2023 | 9 | 2023 |
Three-dimensional structure and optimization of the metallo-β-lactamase inhibitor aspergillomarasmine A K Koteva, D Sychantha, CM Rotondo, C Hobson, JF Britten, GD Wright ACS omega 7 (5), 4170-4184, 2022 | 8 | 2022 |
Synthesis of enantiomerically-enriched N-aryl amino-amides via a Jocic-type reaction C Hobson, MS Perryman, G Kirby, GJ Clarkson, DJ Fox Tetrahedron Letters 59 (44), 3965-3968, 2018 | 6 | 2018 |
Diene incorporation by a dehydratase domain variant in modular polyketide synthases C Hobson, M Jenner, X Jian, D Griffiths, DM Roberts, M Rey-Carrizo, ... Nature chemical biology 18 (12), 1410-1416, 2022 | 3 | 2022 |
Antibiotic Skeletal Diversification via Differential Enoylreductase Recruitment and Module Iteration in trans-Acyltransferase Polyketide Synthases X Jian, F Pang, C Hobson, M Jenner, LM Alkhalaf, GL Challis Journal of the American Chemical Society 146 (9), 6114-6124, 2024 | 1 | 2024 |
Angucyclinones rescue PhLOPSA antibiotic activity by inhibiting Cfr-dependent antibiotic resistance AJ Schaenzer, A Rodriguez Hernandez, K Tsai, C Hobson, DG Fujimori, ... Mbio 14 (6), e01791-23, 2023 | | 2023 |
A widespread family of bacterial gene clusters produces ClpP inhibitors G Wright, E Culp, D Sychantha, C Hobson, A Pawlowski, G Prehna | | 2021 |
A biosynthetic engineering approach to structural diversification of the enacyloxins JR Sargeant University of Warwick, 2021 | | 2021 |
Antimicrobial agents GL Challis, J Xinyun, C Hobson, JSL Masschelein US Patent App. 16/606,845, 2020 | | 2020 |
Phytochemical Investigation of Iphiona aucheri. Structural Revision of Donine Y Dashti, C Hobson, FM Tajabadi, H Rezadoost Chemistry of Natural Compounds 55, 902-907, 2019 | | 2019 |
Biosynthesis and bioengineering of antibiotics in Burkholderia species C Hobson University of Warwick, 2019 | | 2019 |
Antimicrobial Agents. PCT Int. Appl., 2018, WO/2018/193273 J Masschelein, X Jian, C Hobson, GL Challis | | 2018 |
Data for Synthesis of enantiomerically-enriched N-aryl amino-amides via Jocic-type reaction C Hobson, MS Perryman, G Kirby, GJ Clarkson, DJ Fox University of Warwick, Department of Chemistry, 2018 | | 2018 |