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Douglas Loesch
Douglas Loesch
Postdoctoral Fellow, AstraZeneca
Dirección de correo verificada de astrazeneca.com
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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ...
Nature 590 (7845), 290-299, 2021
17262021
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ...
Sequencing of 53, 290-299, 2021
952021
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population
MD Kessler, DP Loesch, JA Perry, NL Heard-Costa, D Taliun, BE Cade, ...
Proceedings of the National Academy of Sciences 117 (5), 2560-2569, 2020
752020
Characterizing the genetic architecture of Parkinson's disease in Latinos
DP Loesch, ARVR Horimoto, K Heilbron, EI Sarihan, M Inca‐Martinez, ...
Annals of neurology 90 (3), 353-365, 2021
742021
Genome‐Wide Analysis of Copy Number Variation in Latin American Parkinson's Disease Patients
EI Sarihan, E Pérez‐Palma, LM Niestroj, D Loesch, M Inca‐Martinez, ...
Movement Disorders 36 (2), 434-441, 2021
182021
Rare non-coding variation identified by large scale whole genome sequencing reveals unexplained heritability of type 2 diabetes
J Wessel, TD Majarian, HM Highland, S Raghavan, MD Szeto, ...
MedRxiv, 2020.11. 13.20221812, 2020
142020
National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Population Genetics Working Group, TD O’Connor, De novo mutations …
MD Kessler, DP Loesch, JA Perry, NL Heard-Costa, D Taliun, BE Cade, ...
Proc. Natl. Acad. Sci. USA 117 (5), 2560-2569, 2020
142020
X‐Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson's Disease
TP Leal, SC Rao, JN French‐Kwawu, MH Gouveia, V Borda, ...
Movement Disorders 38 (9), 1625-1635, 2023
122023
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program
D DiCorpo, SM Gaynor, EM Russell, KE Westerman, LM Raffield, ...
Communications biology 5 (1), 756, 2022
112022
Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas
V Borda, DP Loesch, B Guo, R Laboulaye, D Veliz-Otani, JN French, ...
Cell genomics 4 (11), 2024
92024
Tracing the distribution of European lactase persistence genotypes along the Americas
AC Guimarães Alves, NM Sukow, G Adelman Cipolla, M Mendes, TP Leal, ...
Frontiers in genetics 12, 671079, 2021
92021
Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson's disease cohort
DP Loesch, ARVR Horimoto, EI Sarihan, M Inca-Martinez, E Mason, ...
Parkinsonism & related disorders 102, 7-15, 2022
72022
Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences
OS Burren, RS Dhindsa, SVV Deevi, S Wen, A Nag, J Mitchell, F Hu, ...
Nature Genetics 56 (9), 1832-1840, 2024
42024
Characterizing the genetic architecture of Parkinson’s disease in Latinos
D Loesch, ARVR Horimoto, K Heilbron, EI Sarihan, M Inca-Martinez, ...
medRxiv, 2020.11. 09.20227124, 2020
32020
Parkinson's disease polygenic risk prediction and haplotype analysis in a South American cohort
D Loesch, A Horimoto, E Sarihan, M Cornejo-Olivas, L Torres, ...
MOVEMENT DISORDERS 35, S206-S206, 2020
12020
De novo mutations across 1,465 diverse genomes reveal novel mutational insights and reductions in the Amish founder population
MD Kessler, DP Loesch, JA Perry, NL Heard-Costa, BE Cade, H Wang, ...
bioRxiv, 553214, 2019
12019
Novel Intermediate ATXN10 Alleles in the Healthy Peruvian Population: A Matter of Indigenous American Ethnic Origin
K Milla-Neyra, I Araujo-Aliaga, C Manrique-Enciso, E Sarapura-Castro, ...
The Cerebellum 24 (2), 1-8, 2025
2025
Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities
M Inouye, DP Loesch, M Garg, D Matelska, D Vitsios, X Jiang, SC Ritchie, ...
Nature Portfolio, 2025
2025
Novel expanded ATXN10 alleles in the healthy Peruvian population: a matter of Indigenous American ethnic origin
K Milla-Neyra, I Araujo-Aliaga, C Manrique-Enciso, E Sarapura-Castro, ...
2024
Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities
DP Loesch, M Garg, D Matelska, D Vitsios, X Jiang, SC Ritchie, BB Sun, ...
medRxiv, 2024.03. 15.24304200, 2024
2024
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