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Robin Graf
Robin Graf
MDC Berlin Buch
Dirección de correo verificada de mdc-berlin.de
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Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes
VT Chu, T Weber, R Graf, T Sommermann, K Petsch, U Sack, P Volchkov, ...
BMC biotechnology 16, 1-15, 2016
3262016
PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones
S Sander, T Yasuda, A Franklin, R Graf, DP Calado, S Li, K Imami, ...
Immunity 43 (6), 1075-1086, 2015
2712015
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line
VT Chu, R Graf, T Wirtz, T Weber, J Favret, X Li, K Petsch, NT Tran, ...
Proceedings of the National Academy of Sciences 113 (44), 12514-12519, 2016
1582016
sgRNA sequence motifs blocking efficient CRISPR/Cas9-mediated gene editing
R Graf, X Li, K Rajewsky
Cell reports 26 (5), 1098-1103. e3, 2019
1322019
BCR-dependent lineage plasticity in mature B cells
R Graf, J Seagal, KL Otipoby, KP Lam, S Ayoub, B Zhang, S Sander, ...
Science 363 (6428), 748-753, 2019
1012019
Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation
R Graf, M Munschauer, G Mastrobuoni, F Mayr, U Heinemann, S Kempa, ...
RNA biology 10 (7), 1146-1159, 2013
882013
Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells
NT Tran, T Sommermann, R Graf, J Trombke, J Pempe, K Petsch, R Kühn, ...
Cell reports 28 (13), 3510-3522. e5, 2019
362019
CRISPR-Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia
NT Tran, R Graf, A Wulf-Goldenberg, M Stecklum, G Strauß, R Kühn, ...
Molecular Therapy 28 (12), 2621-2634, 2020
352020
Precise CRISPR-Cas–mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells
NT Tran, E Danner, X Li, R Graf, M Lebedin, K de la Rosa, R Kühn, ...
Science Advances 8 (22), eabm9106, 2022
282022
B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS
K Schmidt, U Sack, R Graf, W Winkler, O Popp, P Mertins, T Sommermann, ...
Frontiers in Immunology 11, 602868, 2020
142020
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification
V Delgado-Benito, M Berruezo-Llacuna, R Altwasser, W Winkler, ...
Journal of Experimental Medicine 217 (10), e20200137, 2020
122020
sgRNA sequence motifs blocking efficient CRISPR/Cas9-mediated gene editing. Cell Rep 26: 1098–1103
R Graf, X Li, VT Chu, K Rajewsky
82019
CRISPR/Cas9-mediated in vitro mutagenesis in GC-like B cells
VT Chu, R Graf, K Rajewsky
Germinal Centers: Methods and Protocols, 135-145, 2017
72017
Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy
H Escobar, S Di Francescantonio, J Smirnova, R Graf, S Müthel, A Marg, ...
Nature Communications 16 (1), 120, 2025
2025
In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis
NT Tran, R Graf, E Acevedo-Ochoa, J Trombke, T Weber, T Sommermann, ...
Leukemia 38 (9), 2003-2015, 2024
2024
Spacer-Nick: Precise Gene Correction in Human Primary Cells with Minimal Off-Target and Unintended On-Target Mutations
NT Tran, EE Danner, X Li, R Graf, M Lebedin, K de la Rosa, R Kuehn, ...
MOLECULAR THERAPY 30 (4), 458-458, 2022
2022
Systematic Genomic Safety Assessment of CRISPR-Based Gene Therapy in Muscle Stem Cells
R Graf, C Stadelmann, HE Fernandez, S Spuler
MOLECULAR THERAPY 30 (4), 544-544, 2022
2022
Molecular characterization of dormant and activated hematopoietic stem cells
R Graf
2010
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Artículos 1–18