| The biology of IQGAP proteins: beyond the cytoskeleton AC Hedman, JM Smith, DB Sacks EMBO reports 16 (4), 427-446, 2015 | 268 | 2015 |
| IQGAPs choreograph cellular signaling from the membrane to the nucleus JM Smith, AC Hedman, DB Sacks Trends in cell biology 25 (3), 171-184, 2015 | 178 | 2015 |
| Phosphatidylinositol 4, 5‐bisphosphate: Targeted production and signaling Y Sun, N Thapa, AC Hedman, RA Anderson Bioessays 35 (6), 513-522, 2013 | 132 | 2013 |
| Agonist-stimulated phosphatidylinositol-3, 4, 5-trisphosphate generation by scaffolded phosphoinositide kinases S Choi, AC Hedman, S Sayedyahossein, N Thapa, DB Sacks, ... Nature Cell Biology 18 (12), 1324-1335, 2016 | 126 | 2016 |
| Endosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sorting Y Sun, AC Hedman, X Tan, NJ Schill, RA Anderson Developmental cell 25 (2), 144-155, 2013 | 98 | 2013 |
| LAPTM4B is a PtdIns (4, 5) P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation X Tan, Y Sun, N Thapa, Y Liao, AC Hedman, RA Anderson The EMBO journal 34 (4), 475-490, 2015 | 90 | 2015 |
| PIP kinases define PI4, 5P 2 signaling specificity by association with effectors S Choi, N Thapa, X Tan, AC Hedman, RA Anderson Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 89 | 2015 |
| IQGAP1 is a novel phosphatidylinositol 4, 5 bisphosphate effector in regulation of directional cell migration S Choi, N Thapa, AC Hedman, Z Li, DB Sacks, RA Anderson The EMBO journal 32 (19), 2617-2630, 2013 | 84 | 2013 |
| IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity S Sayedyahossein, Z Li, AC Hedman, CJ Morgan, DB Sacks Journal of Biological Chemistry 291 (37), 19261-19273, 2016 | 44 | 2016 |
| PIP Kinases from the Cell Membrane to the Nucleus M Schramp, A Hedman, W Li, X Tan, R Anderson Phosphoinositides I: Enzymes of Synthesis and Degradation, 25-59, 2012 | 40 | 2012 |
| Isoform 5 of PIPKIγ regulates the endosomal trafficking and degradation of E-cadherin NJ Schill, AC Hedman, S Choi, RA Anderson Journal of cell science 127 (10), 2189-2203, 2014 | 38 | 2014 |
| Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α Z Li, Y Zhang, AC Hedman, JB Ames, DB Sacks Journal of Biological Chemistry 292 (11), 4614-4622, 2017 | 24 | 2017 |
| Absence of IQGAP1 Protein Leads to Insulin Resistance B Chawla, AC Hedman, S Sayedyahossein, HH Erdemir, Z Li, DB Sacks Journal of Biological Chemistry 292 (8), 3273-3289, 2017 | 23 | 2017 |
| The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling L Thines, FJ Roushar, AC Hedman, DB Sacks Journal of Cell Biology 222 (6), e202205062, 2023 | 19 | 2023 |
| Phosphatidylinositol Phosphate 5-Kinase Iγi2 in Association with Src Controls Anchorage-independent Growth of Tumor Cells N Thapa, S Choi, A Hedman, X Tan, RA Anderson Journal of Biological Chemistry 288 (48), 34707-34718, 2013 | 19 | 2013 |
| IQGAP1 binds AMPK and is required for maximum AMPK activation AC Hedman, Z Li, L Gorisse, S Parvathaneni, CJ Morgan, DB Sacks Journal of Biological Chemistry 296, 2021 | 17 | 2021 |
| Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42 L Gorisse, Z Li, CD Wagner, DK Worthylake, F Zappacosta, AC Hedman, ... Journal of Biological Chemistry 295 (15), 4822-4835, 2020 | 17 | 2020 |
| Ca2+-Dependent Switch of Calmodulin Interaction Mode with Tandem IQ Motifs in the Scaffolding Protein IQGAP1 M Zhang, Z Li, H Jang, AC Hedman, DB Sacks, R Nussinov Biochemistry 58 (49), 4903-4911, 2019 | 16 | 2019 |
| Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras CJ Morgan, AC Hedman, Z Li, DB Sacks Scientific Reports 9 (1), 11057, 2019 | 16 | 2019 |
| An unexpected role for PI4, 5P2 in EGF receptor endosomal trafficking Y Sun, AC Hedman, X Tan, RA Anderson Cell Cycle 12 (13), 1991-1992, 2013 | 6 | 2013 |
