A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function S Feske, Y Gwack, M Prakriya, S Srikanth, SH Puppel, B Tanasa, ... Nature 441 (7090), 179-185, 2006 | 2746 | 2006 |
Calcium oscillations increase the efficiency and specificity of gene expression RE Dolmetsch, K Xu, RS Lewis Nature 392 (6679), 933-936, 1998 | 2454 | 1998 |
Differential activation of transcription factors induced by Ca2+ response amplitude and duration RE Dolmetsch, RS Lewis, CC Goodnow, JI Healy Nature 386 (6627), 855-858, 1997 | 2416 | 1997 |
Store-operated calcium channels M Prakriya, RS Lewis Physiological reviews, 2015 | 1278 | 2015 |
Calcium signaling mechanisms in T lymphocytes RS Lewis Annual review of immunology 19 (1), 497-521, 2001 | 1188 | 2001 |
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1 CY Park, PJ Hoover, FM Mullins, P Bachhawat, ED Covington, S Raunser, ... Cell 136 (5), 876-890, 2009 | 1148 | 2009 |
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores. A Zweifach, RS Lewis Proceedings of the National Academy of Sciences 90 (13), 6295-6299, 1993 | 1016 | 1993 |
Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane MM Wu, JA Buchanan, RM Luik, RS Lewis Journal of Cell Biology 174 (6), 803-813, 2006 | 972 | 2006 |
Molecular basis of calcium signaling in lymphocytes: STIM and ORAI PG Hogan, RS Lewis, A Rao Annual review of immunology 28 (1), 491-533, 2009 | 925 | 2009 |
The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions RM Luik, MM Wu, JA Buchanan, RS Lewis Journal of Cell Biology 174 (6), 815-825, 2006 | 797 | 2006 |
Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells JB Rothbard, TC Jessop, RS Lewis, BA Murray, PA Wender Journal of the American Chemical Society 126 (31), 9506-9507, 2004 | 785 | 2004 |
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells F Lan, AS Lee, P Liang, V Sanchez-Freire, PK Nguyen, L Wang, L Han, ... Cell stem cell 12 (1), 101-113, 2013 | 763 | 2013 |
Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation RM Luik, B Wang, M Prakriya, MM Wu, RS Lewis Nature 454 (7203), 538-542, 2008 | 684 | 2008 |
The molecular choreography of a store-operated calcium channel RS Lewis Nature 446 (7133), 284-287, 2007 | 632 | 2007 |
Mitochondrial regulation of store-operated calcium signaling in T lymphocytes M Hoth, CM Fanger, RS Lewis The Journal of cell biology 137 (3), 633-648, 1997 | 628 | 1997 |
Potassium and calcium channels in lymphocytes RS Lewis, MD Cahalan Annual review of immunology 13 (1), 623-653, 1995 | 609 | 1995 |
Potentiation and inhibition of Ca2+ release-activated Ca2+ channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP3 receptors M Prakriya, RS Lewis The Journal of physiology 536 (Pt 1), 3, 2001 | 602 | 2001 |
Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells. RS Lewis, MD Cahalan Cell regulation 1 (1), 99-112, 1989 | 543 | 1989 |
Different nuclear signals are activated by the B cell receptor during positive versus negative signaling JI Healy, RE Dolmetsch, LA Timmerman, JG Cyster, ML Thomas, ... Immunity 6 (4), 419-428, 1997 | 493 | 1997 |
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction LJ Holsinger, IA Graef, W Swat, T Chi, DM Bautista, L Davidson, RS Lewis, ... Current Biology 8 (10), 563-573, 1998 | 480 | 1998 |