The AlkB family of Fe (II)/α-ketoglutarate-dependent dioxygenases: repairing nucleic acid alkylation damage and beyond BI Fedeles, V Singh, JC Delaney, D Li, JM Essigmann Journal of Biological Chemistry 290 (34), 20734-20742, 2015 | 400 | 2015 |
Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylation N Shrivastav, D Li, JM Essigmann Carcinogenesis 31 (1), 59-70, 2010 | 364 | 2010 |
Characterization of reactive intermediates by multinuclear diffusion-ordered NMR spectroscopy (DOSY) D Li, I Keresztes, R Hopson, PG Williard Accounts of chemical research 42 (2), 270-280, 2009 | 320 | 2009 |
Formula weight prediction by internal reference diffusion-ordered NMR spectroscopy (DOSY) D Li, G Kagan, R Hopson, PG Williard Journal of the American Chemical Society 131 (15), 5627-5634, 2009 | 201 | 2009 |
A small molecule targeting mutagenic translesion synthesis improves chemotherapy JL Wojtaszek, N Chatterjee, J Najeeb, A Ramos, M Lee, K Bian, JY Xue, ... Cell 178 (1), 152-159. e11, 2019 | 177 | 2019 |
Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461 JI Mullins, L Heath, JP Hughes, J Kicha, S Styrchak, KG Wong, U Rao, ... PloS one 6 (1), e15135, 2011 | 99 | 2011 |
Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer BI Fedeles, BD Freudenthal, E Yau, V Singh, S Chang, D Li, JC Delaney, ... Proceedings of the National Academy of Sciences 112 (33), E4571-E4580, 2015 | 89 | 2015 |
Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions F Chen, K Bian, Q Tang, BI Fedeles, V Singh, ZT Humulock, ... Chemical research in toxicology 30 (4), 1102-1110, 2017 | 87 | 2017 |
13C INEPT diffusion-ordered NMR spectroscopy (DOSY) with internal references D Li, R Hopson, W Li, J Liu, PG Williard Organic letters 10 (5), 909-911, 2008 | 73 | 2008 |
DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro K Bian, SAP Lenz, Q Tang, F Chen, R Qi, M Jost, CL Drennan, ... Nucleic acids research 47 (11), 5522-5529, 2019 | 66 | 2019 |
Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5, 6-dihydro-2′-deoxycytidine D Li, BI Fedeles, V Singh, CS Peng, KJ Silvestre, AK Simi, JH Simpson, ... Proceedings of the National Academy of Sciences 111 (32), E3252-E3259, 2014 | 61 | 2014 |
Aggregation Studies of Complexes Containing a Chiral Lithium Amide and n-Butyllithium D Li, C Sun, J Liu, R Hopson, W Li, PG Williard The Journal of Organic Chemistry 73 (6), 2373-2381, 2008 | 61 | 2008 |
Exocyclic Carbons Adjacent to the N6 of Adenine are Targets for Oxidation by the Escherichia coli Adaptive Response Protein AlkB D Li, JC Delaney, CM Page, X Yang, AS Chen, C Wong, CL Drennan, ... Journal of the American Chemical Society 134 (21), 8896-8901, 2012 | 60 | 2012 |
Characterization of a Chiral Enolate Aggregate and Observation of 6Li−1H Scalar Coupling D Li, C Sun, PG Williard Journal of the American Chemical Society 130 (35), 11726-11736, 2008 | 58 | 2008 |
Adaptive response enzyme AlkB preferentially repairs 1-methylguanine and 3-methylthymine adducts in double-stranded DNA F Chen, Q Tang, K Bian, ZT Humulock, X Yang, M Jost, CL Drennan, ... Chemical research in toxicology 29 (4), 687-693, 2016 | 53 | 2016 |
Next-generation sequencing reveals the biological significance of the N 2,3-ethenoguanine lesion in vivo S Chang, BI Fedeles, J Wu, JC Delaney, D Li, L Zhao, PP Christov, E Yau, ... Nucleic acids research 43 (11), 5489-5500, 2015 | 43 | 2015 |
Removal of N-Alkyl Modifications from N2-Alkylguanine and N4-Alkylcytosine in DNA by the Adaptive Response Protein AlkB D Li, BI Fedeles, N Shrivastav, JC Delaney, X Yang, C Wong, CL Drennan, ... Chemical research in toxicology 26 (8), 1182-1187, 2013 | 39 | 2013 |
Direct observation of multiple tautomers of oxythiamine and their recognition by the thiamine pyrophosphate riboswitch V Singh, CS Peng, D Li, K Mitra, KJ Silvestre, A Tokmakoff, JM Essigmann ACS chemical biology 9 (1), 227-236, 2014 | 38 | 2014 |
Analysis of an Asymmetric Addition with a 2:1 Mixed Lithium Amide/n-Butyllithium Aggregate J Liu, D Li, C Sun, PG Williard The Journal of Organic Chemistry 73 (11), 4045-4052, 2008 | 35 | 2008 |
Mechanism of repair of acrolein-and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe (II) dioxygenase AlkB V Singh, BI Fedeles, D Li, JC Delaney, ID Kozekov, A Kozekova, ... Chemical Research in Toxicology 27 (9), 1619-1631, 2014 | 34 | 2014 |