| Vitamin A inhibits the action of LPS on the intestinal epithelial barrier function and tight junction proteins C He, J Deng, X Hu, S Zhou, J Wu, D Xiao, KO Darko, Y Huang, T Tao, ... Food & function 10 (2), 1235-1242, 2019 | 166 | 2019 |
| Design, synthesis, and evaluation of orally available clioquinol-moracin M hybrids as multitarget-directed ligands for cognitive improvement in a rat model of neurodegeneration … Z Wang, Y Wang, B Wang, W Li, L Huang, X Li Journal of Medicinal Chemistry 58 (21), 8616-8637, 2015 | 124 | 2015 |
| Immunogenic camptothesome nanovesicles comprising sphingomyelin-derived camptothecin bilayers for safe and synergistic cancer immunochemotherapy Z Wang, N Little, J Chen, KT Lambesis, KT Le, W Han, AJ Scott, J Lu Nature nanotechnology 16 (10), 1130-1140, 2021 | 123 | 2021 |
| Design, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer’s disease Z Wang, Y Wang, W Li, F Mao, Y Sun, L Huang, X Li ACS chemical neuroscience 5 (10), 952-962, 2014 | 114 | 2014 |
| Design, synthesis, and evaluation of orally bioavailable quinoline–indole derivatives as innovative multitarget-directed ligands: Promotion of cell proliferation in the adult … Z Wang, J Hu, X Yang, X Feng, X Li, L Huang, ASC Chan Journal of medicinal chemistry 61 (5), 1871-1894, 2018 | 87 | 2018 |
| Novel application of metformin combined with targeted drugs on anticancer treatment J Deng, M Peng, Z Wang, S Zhou, D Xiao, J Deng, X Yang, J Peng, ... Cancer science 110 (1), 23-30, 2019 | 61 | 2019 |
| Synthesis and evaluation of selegiline derivatives as monoamine oxidase inhibitor, antioxidant and metal chelator against Alzheimer’s disease S Xie, J Chen, X Li, T Su, Y Wang, Z Wang, L Huang, X Li Bioorganic & Medicinal Chemistry 23 (13), 3722-3729, 2015 | 60 | 2015 |
| Self-assembling prodrug nanotherapeutics for synergistic tumor targeted drug delivery Z Wang, J Chen, N Little, J Lu Acta biomaterialia 111, 20-28, 2020 | 49 | 2020 |
| Camptothesome elicits immunogenic cell death to boost colorectal cancer immune checkpoint blockade Z Wang, W Li, J Park, KM Gonzalez, AJ Scott, J Lu Journal of Controlled Release 349, 929-939, 2022 | 34 | 2022 |
| Design, synthesis and evaluation of clioquinol–ebselen hybrids as multi-target-directed ligands against Alzheimer's disease Z Wang, W Li, Y Wang, X Li, L Huang, X Li RSC advances 6 (9), 7139-7158, 2016 | 28 | 2016 |
| Hybrids consisting of the pharmacophores of salmeterol and roflumilast or phthalazinone: dual β2-adrenoceptor agonists-PDE4 inhibitors for the treatment of COPD A Liu, L Huang, Z Wang, Z Luo, F Mao, W Shan, J Xie, K Lai, X Li Bioorganic & medicinal chemistry letters 23 (5), 1548-1552, 2013 | 25 | 2013 |
| Lipid-based nanotechnology: Liposome Y Jiang, W Li, Z Wang, J Lu Pharmaceutics 16 (1), 34, 2023 | 24 | 2023 |
| Computer-assisted designed “selenoxy–chinolin”: a new catalytic mechanism of the GPx-like cycle and inhibition of metal-free and metal-associated Aβ aggregation Z Wang, Y Wang, W Li, Z Liu, Z Luo, Y Sun, R Wu, L Huang, X Li Dalton Transactions 44 (48), 20913-20925, 2015 | 19 | 2015 |
| Anticancer properties of novel pyrazole‐containing biguanide derivatives with activating the adenosine monophosphate‐activated protein kinase signaling pathway S Zhou, L Xu, M Cao, Z Wang, D Xiao, S Xu, J Deng, X Hu, C He, T Tao, ... Archiv Der Pharmazie 352 (9), 1900075, 2019 | 16 | 2019 |
| Synthesis, biological evaluation and anti-proliferative mechanism of fluorine-containing proguanil derivatives D Xiao, Z Lu, Z Wang, S Zhou, M Cao, J Deng, X Hu, M Peng, C He, J Wu, ... Bioorganic & Medicinal Chemistry 28 (2), 115258, 2020 | 15 | 2020 |
| Synthesis and evaluation of 8-hydroxyquinolin derivatives substituted with (benzo [d][1, 2] selenazol-3 (2H)-one) as effective inhibitor of metal-induced Aβ aggregation and … B Wang, Z Wang, H Chen, CJ Lu, X Li Bioorganic & Medicinal Chemistry 24 (19), 4741-4749, 2016 | 15 | 2016 |
| Sphingomyelin-derived nanovesicles for the delivery of the IDO1 inhibitor epacadostat enhance metastatic and post-surgical melanoma immunotherapy Z Wang, W Li, Y Jiang, TB Tran, LE Cordova, J Chung, M Kim, G Wondrak, ... Nature Communications 14 (1), 7235, 2023 | 12 | 2023 |
| Cholesterol-modified sphingomyelin chimeric lipid bilayer for improved therapeutic delivery Z Wang, W Li, Y Jiang, J Park, KM Gonzalez, X Wu, QY Zhang, J Lu Nature Communications 15 (1), 2073, 2024 | 9 | 2024 |
| Camptothesome potentiates PD-L1 immune checkpoint blockade for improved metastatic triple-negative breast cancer immunochemotherapy Z Wang, LE Cordova, P Chalasani, J Lu Molecular pharmaceutics 19 (12), 4665-4674, 2022 | 9 | 2022 |
| WBQ5187, a multitarget directed agent, ameliorates cognitive impairment in a transgenic mouse model of alzheimer’s disease and modulates cerebral β-amyloid, gliosis, cAMP … Z Wang, M Cao, H Xiang, W Wang, X Feng, X Yang ACS Chemical Neuroscience 10 (12), 4787-4799, 2019 | 9 | 2019 |