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Stephanie Galanie
Stephanie Galanie
Dirección de correo verificada de merck.com
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Complete biosynthesis of opioids in yeast
S Galanie, K Thodey, IJ Trenchard, M Filsinger Interrante, CD Smolke
Science 349 (6252), 1095-1100, 2015
11452015
A microbial biomanufacturing platform for natural and semisynthetic opioids
K Thodey, S Galanie, CD Smolke
Nature chemical biology 10 (10), 837-844, 2014
3342014
Malleability of the SARS-CoV-2 3CL Mpro active-site cavity facilitates binding of clinical antivirals
DW Kneller, S Galanie, G Phillips, HM O'Neill, L Coates, A Kovalevsky
Structure 28 (12), 1313-1320. e3, 2020
1372020
High-throughput virtual screening and validation of a sars-cov-2 main protease noncovalent inhibitor
A Clyde, S Galanie, DW Kneller, H Ma, Y Babuji, B Blaiszik, A Brace, ...
Journal of chemical information and modeling 62 (1), 116-128, 2021
1142021
Mesoscale porous silica as drug delivery vehicles: Synthesis, characterization, and pH-sensitive release profiles
P DeMuth, M Hurley, C Wu, S Galanie, MR Zachariah, P DeShong
Microporous and Mesoporous Materials 141 (1-3), 128-134, 2011
832011
Optimization of yeast-based production of medicinal protoberberine alkaloids
S Galanie, CD Smolke
Microbial cell factories 14, 1-13, 2015
792015
Engineering biosynthetic enzymes for industrial natural product synthesis
S Galanie, D Entwistle, J Lalonde
Natural Product Reports 37 (8), 1122-1143, 2020
752020
Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2
BC Sanders, S Pokhrel, AD Labbe, II Mathews, CJ Cooper, RB Davidson, ...
Nature Communications 14 (1), 1733, 2023
662023
Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Protease
DW Kneller, H Li, S Galanie, G Phillips, A Labbé, KL Weiss, Q Zhang, ...
Journal of medicinal chemistry 64 (23), 17366-17383, 2021
482021
Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro
MA Hameedi, E T. Prates, MR Garvin, II Mathews, BK Amos, ...
Nature Communications 13 (1), 5285, 2022
292022
Hit Expansion of a Noncovalent SARS-CoV-2 Main Protease Inhibitor
J Glaser, A Sedova, S Galanie, DW Kneller, RB Davidson, E Maradzike, ...
ACS pharmacology & translational science 5 (4), 255-265, 2022
252022
Benzylisoquinoline alkaloids (bia) producing microbes, and methods of making and using the same
CD Smolke, C Thodey, I Trenchard, S Galanie
US Patent 9,534,241, 2017
232017
Molecular tools for chemical biotechnology
S Galanie, MS Siddiqui, CD Smolke
Current opinion in biotechnology 24 (6), 1000-1009, 2013
182013
Benzylisoquinoline alkaloids (bia) producing microbes, and methods of making and using the same
CD Smolke, C Thodey, I Trenchard, S Galanie
US Patent 10,017,799, 2018
142018
AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2
RP Joshi, KJ Schultz, JW Wilson, A Kruel, RA Varikoti, CJ Kombala, ...
Journal of Chemical Information and Modeling 63 (5), 1438-1453, 2023
132023
Metabolomic Patterns of Septoria Canker Resistant and Susceptible Populus trichocarpa Genotypes 24 Hours Postinoculation
RR Lenz, KB Louie, KL Søndreli, SS Galanie, JG Chen, W Muchero, ...
Phytopathology® 111 (11), 2052-2066, 2021
82021
Complete absence of thebaine biosynthesis under home-brew fermentation conditions
D Endy, S Galanie, CD Smolke
bioRxiv, 024299, 2015
82015
Validation of a metabolite–GWAS network for Populus trichocarpa family 1 UDP-glycosyltransferases
PMB Saint-Vincent, A Furches, S Galanie, E Teixeira Prates, JL Aldridge, ...
Frontiers in Plant Science 14, 1210146, 2023
62023
An orally administered enzyme therapeutic for homocystinuria that suppresses homocysteine by metabolizing methionine in the gastrointestinal tract
K Skvorak, V Mitchell, L Teadt, KA Franklin, HO Lee, N Kruse, ...
Molecular Genetics and Metabolism 139 (4), 107653, 2023
52023
Engineered glycosyltransferases and steviol glycoside glucosylation methods
J Vroom, SS Galanie, J Liang, J Liu, N Dellas, MA Mayo, D Entwistle
US Patent 11,760,981, 2023
42023
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