Antidepressant and anxiolytic‐like effects in mice lacking the group III metabotropic glutamate receptor mGluR7 JF Cryan, PH Kelly, HC Neijt, G Sansig, PJ Flor, H van Der Putten European Journal of Neuroscience 17 (11), 2409-2417, 2003 | 313 | 2003 |
Bupropion enhances brain reward function and reverses the affective and somatic aspects of nicotine withdrawal in the rat JF Cryan, AW Bruijnzeel, KL Skjei, A Markou Psychopharmacology 168, 347-358, 2003 | 278 | 2003 |
GABAB receptor antagonist-mediated antidepressant-like behavior is serotonin-dependent DA Slattery, S Desrayaud, JF Cryan Journal of Pharmacology and Experimental Therapeutics 312 (1), 290-296, 2005 | 184 | 2005 |
Evaluation of reward processes in an animal model of depression DA Slattery, A Markou, JF Cryan Psychopharmacology 190, 555-568, 2007 | 152 | 2007 |
Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia C Betschart, S Hintermann, D Behnke, S Cotesta, M Fendt, CE Gee, ... Journal of medicinal chemistry 56 (19), 7590-7607, 2013 | 103 | 2013 |
The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors GM Mang, T Dürst, H Bürki, S Imobersteg, D Abramowski, E Schuepbach, ... Sleep 35 (12), 1625-1635, 2012 | 101 | 2012 |
Brain interstitial fluid glutamine homeostasis is controlled by blood–brain barrier SLC7A5/LAT1 amino acid transporter E Dolgodilina, S Imobersteg, E Laczko, T Welt, F Verrey, V Makrides Journal of Cerebral Blood Flow & Metabolism 36 (11), 1929-1941, 2016 | 95 | 2016 |
Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents LH Jacobson, JF Cryan Neuropharmacology 54 (5), 854-862, 2008 | 82 | 2008 |
Onset and offset of aversive events establish distinct memories requiring fear and reward networks M Andreatta, M Fendt, A Mühlberger, MJ Wieser, S Imobersteg, A Yarali, ... Learning & Memory 19 (11), 518-526, 2012 | 80 | 2012 |
Fear-reducing effects of intra-amygdala neuropeptide Y infusion in animal models of conditioned fear: an NPY Y1 receptor independent effect M Fendt, H Bürki, S Imobersteg, K Lingenhöhl, KH McAllister, D Orain, ... Psychopharmacology 206, 291-301, 2009 | 70 | 2009 |
Intra-amygdala injections of neuropeptide S block fear-potentiated startle M Fendt, S Imobersteg, H Bürki, KH McAllister, AW Sailer Neuroscience letters 474 (3), 154-157, 2010 | 52 | 2010 |
Neuropeptide S receptor deficiency modulates spontaneous locomotor activity and the acoustic startle response M Fendt, M Buchi, H Bürki, S Imobersteg, B Ricoux, T Suply, AW Sailer Behavioural brain research 217 (1), 1-9, 2011 | 51 | 2011 |
The effect of mGlu8 deficiency in animal models of psychiatric diseases M Fendt, H Buerki, S Imobersteg, H Van Der Putten, K McAllister, ... Genes, Brain and Behavior 9 (1), 33-44, 2010 | 48 | 2010 |
Differential roles of mGlu7 and mGlu8 in amygdala-dependent behavior and physiology M Fendt, S Imobersteg, D Peterlik, F Chaperon, C Mattes, C Wittmann, ... Neuropharmacology 72, 215-223, 2013 | 45 | 2013 |
Piperidyl amides as novel, potent and orally active mGlu5 receptor antagonists with anxiolytic-like activity C Spanka, R Glatthar, S Desrayaud, M Fendt, D Orain, T Troxler, ... Bioorganic & medicinal chemistry letters 20 (1), 184-188, 2010 | 37 | 2010 |
The gigantocellular reticular nucleus plays a significant role in locomotor recovery after incomplete spinal cord injury AK Engmann, F Bizzozzero, MP Schneider, D Pfyffer, S Imobersteg, ... Journal of Neuroscience 40 (43), 8292-8305, 2020 | 35 | 2020 |
Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse RM O'Connor, DR Thakker, M Schmutz, H van der Putten, D Hoyer, ... Neuropharmacology 72, 66-73, 2013 | 35 | 2013 |
The positive allosteric modulator GS39783 enhances GABAB receptor‐mediated inhibition of cyclic AMP formation in rat striatum in vivo T Gjoni, S Desrayaud, S Imobersteg, S Urwyler Journal of neurochemistry 96 (5), 1416-1422, 2006 | 35 | 2006 |
The effects of muscimol and AMN082 injections into the medial prefrontal cortex on the expression and extinction of conditioned fear in mice MM Morawska, M Fendt Journal of Experimental Biology 215 (8), 1394-1398, 2012 | 31 | 2012 |
Evaluation of Actinium-225 Labeled Minigastrin Analogue [225Ac]Ac-DOTA-PP-F11N for Targeted Alpha Particle Therapy Y Qin, S Imobersteg, A Blanc, S Frank, R Schibli, MP Béhé, M Grzmil Pharmaceutics 12 (11), 1088, 2020 | 29 | 2020 |