| Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 862 | 2018 |
| Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins RM Quadros, H Miura, DW Harms, H Akatsuka, T Sato, T Aida, R Redder, ... Genome biology 18, 1-15, 2017 | 497 | 2017 |
| Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors H Miura, RM Quadros, CB Gurumurthy, M Ohtsuka Nature protocols 13 (1), 195-215, 2018 | 297 | 2018 |
| Mouse genome editing using the CRISPR/Cas system DW Harms, RM Quadros, D Seruggia, M Ohtsuka, G Takahashi, ... Current protocols in human genetics 83 (1), 15.7. 1-15.7. 27, 2014 | 184 | 2014 |
| Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes AM Jacobi, GR Rettig, R Turk, MA Collingwood, SA Zeiner, RM Quadros, ... Methods 121, 16-28, 2017 | 165 | 2017 |
| Cleavage by caspase 8 and mitochondrial membrane association activate the BH3-only protein Bid during TRAIL-induced apoptosis K Huang, J Zhang, KL O’Neill, CB Gurumurthy, RM Quadros, Y Tu, X Luo Journal of Biological Chemistry 291 (22), 11843-11851, 2016 | 156 | 2016 |
| Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I N Gomez-Ospina, SG Scharenberg, N Mostrel, RO Bak, S Mantri, ... Nature Communications, 2019 | 119 | 2019 |
| CD4+ effector T cells accelerate Alzheimer’s disease in mice J Machhi, P Yeapuri, Y Lu, E Foster, R Chikhale, J Herskovitz, ... Journal of neuroinflammation 18, 1-23, 2021 | 93 | 2021 |
| Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation CB Gurumurthy, AR O’brien, RM Quadros, J Adams, P Alcaide, S Ayabe, ... Genome biology 20 (1), 1-14, 2019 | 88 | 2019 |
| Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice H Wu, C Petitpré, P Fontanet, A Sharma, C Bellardita, RM Quadros, ... Nature communications 12 (1), 1026, 2021 | 80 | 2021 |
| CRISPR: a versatile tool for both forward and reverse genetics research CB Gurumurthy, M Grati, M Ohtsuka, SLP Schilit, RM Quadros, XZ Liu Human genetics 135, 971-976, 2016 | 67 | 2016 |
| Genetically modified mouse models to help fight COVID-19 CB Gurumurthy, RM Quadros, GP Richardson, LY Poluektova, ... Nature protocols 15 (12), 3777-3787, 2020 | 40 | 2020 |
| Ca2+ sensor synaptotagmin-1 mediates exocytosis in mammalian photoreceptors JJ Grassmeyer, AL Cahill, CL Hays, C Barta, RM Quadros, ... Elife 8, e45946, 2019 | 36 | 2019 |
| Insertion of sequences at the original provirus integration site of mouseROSA26 locus using the CRISPR/Cas9 system RM Quadros, DW Harms, M Ohtsuka, CB Gurumurthy FEBS open bio 5 (1), 191-197, 2015 | 36 | 2015 |
| Sedative effect of Clozapine is a function of 5-HT2A and environmental novelty RS Joshi, R Quadros, M Drumm, R Ain, MM Panicker European Neuropsychopharmacology 27 (1), 70-81, 2017 | 22 | 2017 |
| Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening CB Gurumurthy, PS Joshi, SG Kurz, M Ohtsuka, RM Quadros, DW Harms, ... International Journal of Genomics 2015 (1), 735845, 2015 | 21 | 2015 |
| Pronuclear Injection‐Based Targeted Transgenesis SLP Schilit, M Ohtsuka, RM Quadros, CB Gurumurthy Current protocols in human genetics 91 (1), 15.10. 1-15.10. 28, 2016 | 17 | 2016 |
| Synaptotagmins 1 and 7 in vesicle release from rods of mouse retina CS Mesnard, CL Hays, CL Barta, AL Sladek, JJ Grassmeyer, KK Hinz, ... Experimental eye research 225, 109279, 2022 | 12 | 2022 |
| Antiretroviral drug metabolism in humanized PXR-CAR-CYP3A-NOG mice JEM McMillan, DA Cobb, Z Lin, MG Banoub, RS Dagur, AAB Woods, ... Journal of Pharmacology and Experimental Therapeutics 365 (2), 272-280, 2018 | 12 | 2018 |
| Prototype mouse models for researching SEND-based mRNA delivery and gene therapy CB Gurumurthy, RM Quadros, M Ohtsuka Nature protocols 17 (10), 2129-2138, 2022 | 10 | 2022 |