Direct detection of DNA methylation during single-molecule, real-time sequencing BA Flusberg, DR Webster, JH Lee, KJ Travers, EC Olivares, TA Clark, ... Nature methods 7 (6), 461-465, 2010 | 1728 | 2010 |
HITS-CLIP yields genome-wide insights into brain alternative RNA processing DD Licatalosi, A Mele, JJ Fak, J Ule, M Kayikci, SW Chi, TA Clark, ... Nature 456 (7221), 464-469, 2008 | 1602 | 2008 |
Nova regulates brain-specific splicing to shape the synapse J Ule, A Ule, J Spencer, A Williams, JS Hu, M Cline, H Wang, T Clark, ... Nature genetics 37 (8), 844-852, 2005 | 610 | 2005 |
Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay JZ Ni, L Grate, JP Donohue, C Preston, N Nobida, G O’Brien, L Shiue, ... Genes & development 21 (6), 708-718, 2007 | 604 | 2007 |
Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array PJ Gardina, TA Clark, B Shimada, MK Staples, Q Yang, J Veitch, ... BMC genomics 7, 1-18, 2006 | 589 | 2006 |
Unveiling the complexity of the maize transcriptome by single-molecule long-read sequencing B Wang, E Tseng, M Regulski, TA Clark, T Hon, Y Jiao, Z Lu, A Olson, ... Nature communications 7 (1), 11708, 2016 | 567 | 2016 |
Genomewide analysis of mRNA processing in yeast using splicing-specific microarrays TA Clark, CW Sugnet, M Ares Jr Science 296 (5569), 907-910, 2002 | 527 | 2002 |
Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing G Fang, D Munera, DI Friedman, A Mandlik, MC Chao, O Banerjee, ... Nature biotechnology 30 (12), 1232-1239, 2012 | 403 | 2012 |
Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy H Du, MS Cline, RJ Osborne, DL Tuttle, TA Clark, JP Donohue, MP Hall, ... Nature structural & molecular biology 17 (2), 187-193, 2010 | 395 | 2010 |
Characterization of DNA methyltransferase specificities using single-molecule, real-time DNA sequencing TA Clark, IA Murray, RD Morgan, AO Kislyuk, KE Spittle, M Boitano, ... Nucleic acids research 40 (4), e29-e29, 2012 | 361 | 2012 |
Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae S Conlan, PJ Thomas, C Deming, M Park, AF Lau, JP Dekker, ES Snitkin, ... Science translational medicine 6 (254), 254ra126-254ra126, 2014 | 360 | 2014 |
The epigenomic landscape of prokaryotes MJ Blow, TA Clark, CG Daum, AM Deutschbauer, A Fomenkov, R Fries, ... PLoS genetics 12 (2), e1005854, 2016 | 356 | 2016 |
Discovery of tissue-specific exons using comprehensive human exon microarrays TA Clark, AC Schweitzer, TX Chen, MK Staples, G Lu, H Wang, A Williams, ... Genome biology 8, 1-16, 2007 | 340 | 2007 |
The methylomes of six bacteria IA Murray, TA Clark, RD Morgan, M Boitano, BP Anton, K Luong, ... Nucleic acids research 40 (22), 11450-11462, 2012 | 319 | 2012 |
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB M Llorian, S Schwartz, TA Clark, D Hollander, LY Tan, R Spellman, ... Nature structural & molecular biology 17 (9), 1114-1123, 2010 | 302 | 2010 |
Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine CX Song, TA Clark, XY Lu, A Kislyuk, Q Dai, SW Turner, C He, J Korlach Nature methods 9 (1), 75-77, 2012 | 292 | 2012 |
Analysis of alternative splicing associated with aging and neurodegeneration in the human brain JR Tollervey, Z Wang, T Hortobágyi, JT Witten, K Zarnack, M Kayikci, ... Genome research 21 (10), 1572-1582, 2011 | 275 | 2011 |
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation N Salomonis, CR Schlieve, L Pereira, C Wahlquist, A Colas, AC Zambon, ... Proceedings of the National Academy of Sciences 107 (23), 10514-10519, 2010 | 269 | 2010 |
Unusual intron conservation near tissue-regulated exons found by splicing microarrays CW Sugnet, K Srinivasan, TA Clark, G O'Brien, MS Cline, H Wang, ... PLoS computational biology 2 (1), e4, 2006 | 246 | 2006 |
Evaluation of genetic variation contributing to differences in gene expression between populations W Zhang, S Duan, EO Kistner, WK Bleibel, RS Huang, TA Clark, TX Chen, ... The American Journal of Human Genetics 82 (3), 631-640, 2008 | 244 | 2008 |