Recent developments of novel pharmacologic therapeutics for prevention of chemotherapy-induced peripheral neuropathy S Hu, KM Huang, EJ Adams, CL Loprinzi, MB Lustberg Clinical Cancer Research 25 (21), 6295-6301, 2019 | 84 | 2019 |
OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity AF Leblanc, JA Sprowl, P Alberti, A Chiorazzi, WD Arnold, AA Gibson, ... The Journal of clinical investigation 128 (2), 816-825, 2018 | 73 | 2018 |
Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice KM Huang, AF Leblanc, ME Uddin, JY Kim, M Chen, ED Eisenmann, ... The Journal of clinical investigation 130 (9), 4601-4606, 2020 | 61 | 2020 |
Targeting OCT3 attenuates doxorubicin-induced cardiac injury KM Huang, M Zavorka Thomas, T Magdy, ED Eisenmann, ME Uddin, ... Proceedings of the National Academy of Sciences 118 (5), e2020168118, 2021 | 60 | 2021 |
Prevention of skin carcinogenesis by the β-blocker carvedilol A Chang, S Yeung, A Thakkar, KM Huang, MM Liu, RS Kanassatega, ... Cancer prevention research 8 (1), 27-36, 2015 | 56 | 2015 |
Murine Pharmacokinetic Studies AF Leblanc, KM Huang, ME Uddin, JT Anderson, M Chen, S Hu Bio-Protocol, 2018 | 47 | 2018 |
Topically applied carvedilol attenuates solar ultraviolet radiation induced skin carcinogenesis KM Huang, S Liang, S Yeung, E Oiyemhonlan, KH Cleveland, C Parsa, ... Cancer prevention research 10 (10), 598-606, 2017 | 42 | 2017 |
Regulation of OATP1B1 function by tyrosine kinase–mediated phosphorylation ER Hayden, M Chen, KZ Pasquariello, AA Gibson, JJ Petti, S Shen, J Qu, ... Clinical Cancer Research 27 (15), 4301-4310, 2021 | 38 | 2021 |
Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients J Yuda, C Will, DC Phillips, L Abraham, C Alvey, A Avigdor, W Buck, ... Communications Medicine 3 (1), 154, 2023 | 26 | 2023 |
Role of SLC transporters in toxicity induced by anticancer drugs KM Huang, ME Uddin, D DiGiacomo, MB Lustberg, S Hu, A Sparreboom Expert opinion on drug metabolism & toxicology 16 (6), 493-506, 2020 | 25 | 2020 |
TP-0903 is active in models of drug-resistant acute myeloid leukemia JY Jeon, DR Buelow, DA Garrison, M Niu, ED Eisenmann, KM Huang, ... JCI insight 5 (23), 2020 | 24 | 2020 |
Phosphoproteome profiling provides insight into the mechanism of action for carvedilol‐mediated cancer prevention KH Cleveland, S Yeung, KM Huang, S Liang, BT Andresen, Y Huang Molecular carcinogenesis 57 (8), 997-1007, 2018 | 24 | 2018 |
Drug transporters and anthracycline-induced cardiotoxicity KM Huang, S Hu, A Sparreboom Pharmacogenomics 19 (11), 883-888, 2018 | 22 | 2018 |
Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1 ME Uddin, DA Garrison, K Kim, Y Jin, ED Eisenmann, KM Huang, ... Frontiers in Pharmacology 12, 644342, 2021 | 21 | 2021 |
Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition Y Bai, JY Kim, B Bisunke, LA Jayne, JA Silvaroli, MS Balzer, M Gandhi, ... Kidney international 100 (6), 1214-1226, 2021 | 20 | 2021 |
Effects of bioactive constituents in the Traditional Chinese Medicinal formula Si–Wu–Tang on Nrf2 signaling and neoplastic cellular transformation MM Liu, KM Huang, L Qian, P Chatterjee, S Zhang, R Li, S Zhou, Z Wang, ... Phytomedicine 40, 1-9, 2018 | 19 | 2018 |
Carvedilol inhibits EGF-mediated JB6 P+ colony formation through a mechanism independent of adrenoceptors KH Cleveland, S Liang, A Chang, KM Huang, S Chen, L Guo, Y Huang, ... PLoS One 14 (5), e0217038, 2019 | 16 | 2019 |
Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma BA Carneiro, KP Papadopoulos, JH Strickler, AB Lassman, SN Waqar, ... Neuro-Oncology Advances 5 (1), vdac183, 2023 | 9 | 2023 |
Solute carrier transportome in chemotherapy-induced adverse drug reactions JT Anderson, KM Huang, MB Lustberg, A Sparreboom, S Hu Targets of Cancer Diagnosis and Treatment: Ion Transport in Tumor Biology …, 2020 | 9 | 2020 |
Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy Y Li, T Drabison, M Nepal, RH Ho, AF Leblanc, AA Gibson, Y Jin, W Yang, ... JCI insight 8 (14), 2023 | 8 | 2023 |