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Kevin M Huang
Kevin M Huang
Research Scientist
Dirección de correo verificada de osu.edu - Página principal
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Recent developments of novel pharmacologic therapeutics for prevention of chemotherapy-induced peripheral neuropathy
S Hu, KM Huang, EJ Adams, CL Loprinzi, MB Lustberg
Clinical Cancer Research 25 (21), 6295-6301, 2019
842019
OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity
AF Leblanc, JA Sprowl, P Alberti, A Chiorazzi, WD Arnold, AA Gibson, ...
The Journal of clinical investigation 128 (2), 816-825, 2018
732018
Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice
KM Huang, AF Leblanc, ME Uddin, JY Kim, M Chen, ED Eisenmann, ...
The Journal of clinical investigation 130 (9), 4601-4606, 2020
612020
Targeting OCT3 attenuates doxorubicin-induced cardiac injury
KM Huang, M Zavorka Thomas, T Magdy, ED Eisenmann, ME Uddin, ...
Proceedings of the National Academy of Sciences 118 (5), e2020168118, 2021
602021
Prevention of skin carcinogenesis by the β-blocker carvedilol
A Chang, S Yeung, A Thakkar, KM Huang, MM Liu, RS Kanassatega, ...
Cancer prevention research 8 (1), 27-36, 2015
562015
Murine Pharmacokinetic Studies
AF Leblanc, KM Huang, ME Uddin, JT Anderson, M Chen, S Hu
Bio-Protocol, 2018
472018
Topically applied carvedilol attenuates solar ultraviolet radiation induced skin carcinogenesis
KM Huang, S Liang, S Yeung, E Oiyemhonlan, KH Cleveland, C Parsa, ...
Cancer prevention research 10 (10), 598-606, 2017
422017
Regulation of OATP1B1 function by tyrosine kinase–mediated phosphorylation
ER Hayden, M Chen, KZ Pasquariello, AA Gibson, JJ Petti, S Shen, J Qu, ...
Clinical Cancer Research 27 (15), 4301-4310, 2021
382021
Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients
J Yuda, C Will, DC Phillips, L Abraham, C Alvey, A Avigdor, W Buck, ...
Communications Medicine 3 (1), 154, 2023
262023
Role of SLC transporters in toxicity induced by anticancer drugs
KM Huang, ME Uddin, D DiGiacomo, MB Lustberg, S Hu, A Sparreboom
Expert opinion on drug metabolism & toxicology 16 (6), 493-506, 2020
252020
TP-0903 is active in models of drug-resistant acute myeloid leukemia
JY Jeon, DR Buelow, DA Garrison, M Niu, ED Eisenmann, KM Huang, ...
JCI insight 5 (23), 2020
242020
Phosphoproteome profiling provides insight into the mechanism of action for carvedilol‐mediated cancer prevention
KH Cleveland, S Yeung, KM Huang, S Liang, BT Andresen, Y Huang
Molecular carcinogenesis 57 (8), 997-1007, 2018
242018
Drug transporters and anthracycline-induced cardiotoxicity
KM Huang, S Hu, A Sparreboom
Pharmacogenomics 19 (11), 883-888, 2018
222018
Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1
ME Uddin, DA Garrison, K Kim, Y Jin, ED Eisenmann, KM Huang, ...
Frontiers in Pharmacology 12, 644342, 2021
212021
Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition
Y Bai, JY Kim, B Bisunke, LA Jayne, JA Silvaroli, MS Balzer, M Gandhi, ...
Kidney international 100 (6), 1214-1226, 2021
202021
Effects of bioactive constituents in the Traditional Chinese Medicinal formula Si–Wu–Tang on Nrf2 signaling and neoplastic cellular transformation
MM Liu, KM Huang, L Qian, P Chatterjee, S Zhang, R Li, S Zhou, Z Wang, ...
Phytomedicine 40, 1-9, 2018
192018
Carvedilol inhibits EGF-mediated JB6 P+ colony formation through a mechanism independent of adrenoceptors
KH Cleveland, S Liang, A Chang, KM Huang, S Chen, L Guo, Y Huang, ...
PLoS One 14 (5), e0217038, 2019
162019
Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma
BA Carneiro, KP Papadopoulos, JH Strickler, AB Lassman, SN Waqar, ...
Neuro-Oncology Advances 5 (1), vdac183, 2023
92023
Solute carrier transportome in chemotherapy-induced adverse drug reactions
JT Anderson, KM Huang, MB Lustberg, A Sparreboom, S Hu
Targets of Cancer Diagnosis and Treatment: Ion Transport in Tumor Biology …, 2020
92020
Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy
Y Li, T Drabison, M Nepal, RH Ho, AF Leblanc, AA Gibson, Y Jin, W Yang, ...
JCI insight 8 (14), 2023
82023
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