| An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients CA Spina, J Anderson, NM Archin, A Bosque, J Chan, M Famiglietti, ... PLoS pathogens 9 (12), e1003834, 2013 | 468 | 2013 |
| The HBV drug entecavir—effects on HIV-1 replication and resistance MA McMahon, BL Jilek, TP Brennan, L Shen, Y Zhou, M Wind-Rotolo, ... New England Journal of Medicine 356 (25), 2614-2621, 2007 | 369 | 2007 |
| Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation HC Yang, S Xing, L Shan, K O’Connell, J Dinoso, A Shen, Y Zhou, ... The Journal of clinical investigation 119 (11), 3473-3486, 2009 | 306 | 2009 |
| BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism D Boehm, V Calvanese, RD Dar, S Xing, S Schroeder, L Martins, K Aull, ... Cell cycle 12 (3), 452-462, 2013 | 277 | 2013 |
| Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation S Xing, CK Bullen, NS Shroff, L Shan, HC Yang, JL Manucci, S Bhat, ... Journal of virology 85 (12), 6060-6064, 2011 | 238 | 2011 |
| Transcriptional reprogramming during effector-to-memory transition renders CD4+ T cells permissive for latent HIV-1 infection L Shan, K Deng, H Gao, S Xing, AA Capoferri, CM Durand, SA Rabi, ... Immunity 47 (4), 766-775. e3, 2017 | 210 | 2017 |
| Targeting HIV latency: pharmacologic strategies toward eradication S Xing, RF Siliciano Drug discovery today 18 (11-12), 541-551, 2013 | 187 | 2013 |
| A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs L Shen, SA Rabi, AR Sedaghat, L Shan, J Lai, S Xing, RF Siliciano Science translational medicine 3 (91), 91ra63-91ra63, 2011 | 74 | 2011 |
| Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation S Xing, S Bhat, NS Shroff, H Zhang, JA Lopez, JB Margolick, JO Liu, ... Journal of antimicrobial chemotherapy 67 (2), 398-403, 2012 | 56 | 2012 |
| Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells L Shan, S Xing, HC Yang, H Zhang, JB Margolick, RF Siliciano Journal of Antimicrobial Chemotherapy 69 (1), 28-33, 2014 | 39 | 2014 |
Liang ShanWashington University in St. LouisDirección de correo verificada de wustl.edu