Gene therapy clinical trials worldwide to 2012–an update SL Ginn, IE Alexander, ML Edelstein, MR Abedi, J Wixon The journal of gene medicine 15 (2), 65-77, 2013 | 1059 | 2013 |
Gene therapy clinical trials worldwide to 2017: An update SL Ginn, AK Amaya, IE Alexander, M Edelstein, MR Abedi The journal of gene medicine 20 (5), e3015, 2018 | 1005 | 2018 |
Identification of liver-specific enhancer–promoter activity in the 3′ untranslated region of the wild-type AAV2 genome GJ Logan, AP Dane, CV Hallwirth, CM Smyth, EE Wilkie, AK Amaya, ... Nature genetics 49 (8), 1267-1273, 2017 | 119 | 2017 |
Adeno-associated virus and lentivirus vectors mediate efficient and sustained transduction of cultured mouse and human dorsal root ganglia sensory neurons J Fleming, SL Ginn, RP Weinberger, TN Trahair, JA Smythe, IE Alexander Human gene therapy 12 (1), 77-86, 2001 | 100 | 2001 |
Bidirectional promoter interference between two widely used internal heterologous promoters in a late-generation lentiviral construct JA Curtin, AP Dane, A Swanson, IE Alexander, SL Ginn Gene therapy 15 (5), 384-390, 2008 | 92 | 2008 |
Fibroblasts can be genetically modified to produce excitable cells capable of electrical coupling E Kizana, SL Ginn, DG Allen, DL Ross, IE Alexander Circulation 111 (4), 394-398, 2005 | 72 | 2005 |
Lymphomagenesis in SCID-X1 mice following lentivirus-mediated phenotype correction independent of insertional mutagenesis and γc overexpression SL Ginn, SHY Liao, AP Dane, M Hu, J Hyman, JW Finnie, M Zheng, ... Molecular therapy 18 (5), 965-976, 2010 | 66 | 2010 |
Treatment of an infant with X‐linked severe combined immunodeficiency (SCID‐X1) by gene therapy in Australia SL Ginn, JA Curtin, CM Smyth, M Latham, SC Cunningham, M Zheng, ... Medical journal of Australia 182 (9), 458-463, 2005 | 64 | 2005 |
Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes: novel basis for modulation of cardiac conduction by gene therapy E Kizana, CY Chang, E Cingolani, GA Ramirez-Correa, RB Sekar, ... Circulation research 100 (11), 1597-1604, 2007 | 54 | 2007 |
Myoblast sensitivity and fibroblast insensitivity to osteogenic conversion by BMP-2 correlates with the expression of Bmpr-1a R Liu, SL Ginn, M Lek, KN North, IE Alexander, DG Little, A Schindeler BMC musculoskeletal disorders 10, 1-12, 2009 | 53 | 2009 |
The TetA(K) Tetracycline/H+ Antiporter from Staphylococcus aureus: Mutagenesis and Functional Analysis of Motif C SL Ginn, MH Brown, RA Skurray Journal of bacteriology 182 (6), 1492-1498, 2000 | 53 | 2000 |
Restoring the natural tropism of AAV2 vectors for human liver M Cabanes-Creus, CV Hallwirth, A Westhaus, BH Ng, SHY Liao, E Zhu, ... Science Translational Medicine 12 (560), eaba3312, 2020 | 52 | 2020 |
Partial correction of sensitivity to oxidant stress in Friedreich ataxia patient fibroblasts by frataxin-encoding adeno-associated virus and lentivirus vectors J Fleming, A Spinoulas, M Zheng, SC Cunningham, SL Ginn, RC McQuilty, ... Human gene therapy 16 (8), 947-956, 2005 | 50 | 2005 |
Fibroblasts modulate cardiomyocyte excitability: implications for cardiac gene therapy E Kizana, SL Ginn, CM Smyth, A Boyd, SP Thomas, DG Allen, DL Ross, ... Gene Therapy 13 (22), 1611-1615, 2006 | 49 | 2006 |
Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence CT Deakin, JJ Deakin, SL Ginn, P Young, D Humphreys, CM Suter, ... Nucleic acids research 42 (16), e129-e129, 2014 | 45 | 2014 |
Promoter interference mediated by the U3 region in early-generation HIV-1–derived lentivirus vectors can influence detection of transgene expression in a cell-type and species … SL Ginn, J Fleming, PB Rowe, IE Alexander Human gene therapy 14 (12), 1127-1137, 2003 | 45 | 2003 |
Membrane topology of the metal-tetracycline/H+ antiporter TetA (K) from Staphylococcus aureus SL Ginn, MH Brown, RA Skurray Journal of bacteriology 179 (11), 3786-3789, 1997 | 39 | 1997 |
Codon-optimization of wild-type adeno-associated virus capsid sequences enhances DNA family shuffling while conserving functionality M Cabanes-Creus, SL Ginn, AK Amaya, SHY Liao, A Westhaus, ... Molecular Therapy-Methods & Clinical Development 12, 71-84, 2019 | 38 | 2019 |
Lentivirus vector‐mediated gene transfer to the developing bronchiolar airway epithelium in the fetal lamb ZY Yu, K McKay, P van Asperen, M Zheng, J Fleming, SL Ginn, E Kizana, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2007 | 35 | 2007 |
Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes SL Ginn, AK Amaya, SHY Liao, E Zhu, SC Cunningham, M Lee, ... JHEP Reports 2 (1), 100065, 2020 | 29 | 2020 |