CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition D Gallo, JTF Young, J Fourtounis, G Martino, A Álvarez-Quilón, C Bernier, ... Nature 604 (7907), 749-756, 2022 | 136 | 2022 |
Arming an oncolytic herpes simplex virus type 1 with a single-chain fragment variable antibody against PD-1 for experimental glioblastoma therapy C Passaro, Q Alayo, I DeLaura, J McNulty, K Grauwet, H Ito, V Bhaskaran, ... Clinical Cancer Research 25 (1), 290-299, 2019 | 122 | 2019 |
The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma V Bhaskaran, MO Nowicki, M Idriss, MA Jimenez, G Lugli, JL Hayes, ... Nature communications 10 (1), 442, 2019 | 112 | 2019 |
The CIP2A–TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer S Adam, SE Rossi, N Moatti, M De Marco Zompit, Y Xue, TF Ng, ... Nature cancer 2 (12), 1357-1371, 2021 | 86 | 2021 |
Tumor-derived fibulin-3 activates pro-invasive NF-κB signaling in glioblastoma cells and their microenvironment MS Nandhu, A Kwiatkowska, V Bhaskaran, J Hayes, B Hu, MS Viapiano Oncogene 36 (34), 4875-4886, 2017 | 37 | 2017 |
Discovery of an orally bioavailable and selective PKMYT1 inhibitor, RP-6306 J Szychowski, R Papp, E Dietrich, B Liu, F Vallée, ME Leclaire, ... Journal of medicinal chemistry 65 (15), 10251-10284, 2022 | 34 | 2022 |
Development of a function-blocking antibody against fibulin-3 as a targeted reagent for glioblastoma MS Nandhu, P Behera, V Bhaskaran, SL Longo, LM Barrera-Arenas, ... Clinical Cancer Research 24 (4), 821-833, 2018 | 32 | 2018 |
Engineering, delivery, and biological validation of artificial microRNA clusters for gene therapy applications V Bhaskaran, Y Yao, F Bei, P Peruzzi Nature protocols 14 (12), 3538-3553, 2019 | 16 | 2019 |
Structure of an amidohydrolase, SACOL0085, from methicillin-resistant Staphylococcus aureus COL TS Girish, B Vivek, M Colaco, S Misquith, B Gopal Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 11 | 2013 |
Correction: arming an oncolytic herpes simplex virus type 1 with a single-chain fragment variable antibody against PD-1 for experimental glioblastoma therapy C Passaro, Q Alayo, I DeLaura, J McNulty, K Grauwet, H Ito, V Bhaskaran, ... Clinical Cancer Research 26 (3), 758-758, 2020 | 8 | 2020 |
The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma. Nat Commun. 2019; 10: 442 V Bhaskaran, MO Nowicki, M Idriss, MA Jimenez, G Lugli, JL Hayes, ... DOI: https://doi. org/10.1038/s41467-019-08390-z. PMID: https://www. ncbi …, 0 | 5 | |
CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers. bioRxiv Published online February 8, 2021 S Adam | 2 | 2021 |
Characterization of functionally associated miRNAs in glioblastoma and their engineering into artificial clusters for gene therapy V Bhaskaran, P Peruzzi Journal of visualized experiments: JoVE, 10.3791/60215, 2019 | 2 | 2019 |
Abstract C163: KRAS alterations combined with TP53 mutations as novel synthetic lethal genomic lesions for PKMYT1 inhibition ML Hyer, J Fourtounis, D Gallo, V Bhaskaran, R Stocco, R Kryczka, ... Molecular Cancer Therapeutics 22 (12_Supplement), C163-C163, 2023 | 1 | 2023 |
MicroRNAs in brain cancer: look at the forest, not at the tree P Peruzzi, V Bhaskaran Journal of Experimental Neuroscience 13, 1179069519839693, 2019 | 1 | 2019 |
The PKMYT1 inhibitor RP-6306 has synergistic efficacy with carboplatin in CCNE1 amplified tumor models J Fourtounis, D Gallo, A Roulston, R Stocco, G Martino, S Fournier, ... European Journal of Cancer 174, S61, 2022 | | 2022 |
Regulation of the protease ADAM17 by extracellular signals drives pro-tumoral programs in glioblastoma cells and their microenvironment. NM Sobhana, V Bhaskaran, B Hu, M Viapiano SNO 2017 Annual Meeting, 2017 | | 2017 |
Regulation Of The Protease Adam17 By Extracellular Signals Drives Pro-tumoral Programs In Glioblastoma Cells And Their Microenvironment. MS Nandhu, V Bhaskaran, B Hu, M Viapiano Neuro-oncology 19 (suppl_6), vi253, 2017 | | 2017 |
An Engineered microrna Cluster For Broad Targeting Of Epigenetic Complexes In Gbm V Bhaskaran, M Idriss, SE Lawler, EA Chiocca, PP Peruzzi Neuro-oncology 19 (suppl_6), vi88, 2017 | | 2017 |
GENT-24. LONG NON-CODING RNA CRNDE AS A POTENTIAL EGFR-REGULATED ONCOGENE IN GLIOMA P Peruzzi, V Bhaskaran, M Idriss, J Godlewski, EA Chiocca, SE Lawler, ... NEURO-ONCOLOGY, 2016 | | 2016 |