Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination MMC Lam, KL Wyres, S Duchêne, RR Wick, LM Judd, YH Gan, CH Hoh, ... Nature communications 9 (1), 2703, 2018 | 272 | 2018 |
Flagella Are Virulence Determinants of Burkholderia pseudomallei KL Chua, YY Chan, YH Gan Infection and immunity 71 (4), 1622-1629, 2003 | 219 | 2003 |
Caspase‐1 dependent macrophage death induced by Burkholderia pseudomallei GW Sun, J Lu, S Pervaiz, WP Cao, YH Gan Cellular microbiology 7 (10), 1447-1458, 2005 | 170 | 2005 |
Characterization of Burkholderia pseudomallei infection and identification of novel virulence factors using a Caenorhabditis elegans host system YH Gan, KL Chua, HH Chua, B Liu, CS Hii, HL Chong, P Tan Molecular microbiology 44 (5), 1185-1197, 2002 | 147 | 2002 |
Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population IR Lee, JS Molton, KL Wyres, C Gorrie, J Wong, CH Hoh, J Teo, ... Scientific reports 6 (1), 29316, 2016 | 140 | 2016 |
Model of Differential Susceptibility to Mucosal Burkholderia pseudomallei Infection B Liu, GC Koo, EH Yap, KL Chua, YH Gan Infection and immunity 70 (2), 504-511, 2002 | 139 | 2002 |
Metagenome-wide association analysis identifies microbial determinants of post-antibiotic ecological recovery in the gut KR Chng, TS Ghosh, YH Tan, T Nandi, IR Lee, AHQ Ng, C Li, ... Nature ecology & evolution 4 (9), 1256-1267, 2020 | 135 | 2020 |
Glutathione deficiency in type 2 diabetes impairs cytokine responses and control of intracellular bacteria KS Tan, KO Lee, KC Low, AM Gamage, Y Liu, GYG Tan, HQV Koh, ... The Journal of clinical investigation 122 (6), 2289-2300, 2012 | 129 | 2012 |
Regulation of type VI secretion system during Burkholderia pseudomallei infection Y Chen, J Wong, GW Sun, Y Liu, GYG Tan, YH Gan Infection and immunity 79 (8), 3064-3073, 2011 | 105 | 2011 |
Suppression of host innate immune response by Burkholderia pseudomallei through the virulence factor TssM KS Tan, Y Chen, YC Lim, GYG Tan, Y Liu, YT Lim, P MacAry, YH Gan The Journal of Immunology 184 (9), 5160-5171, 2010 | 104 | 2010 |
The BpsIR Quorum-Sensing System of Burkholderia pseudomallei Y Song, C Xie, YM Ong, YH Gan, KL Chua Journal of bacteriology 187 (2), 785-790, 2005 | 102 | 2005 |
Interaction between Burkholderia pseudomallei and the Host Immune Response: Sleeping with the Enemy? YH Gan The Journal of infectious diseases 192 (10), 1845-1850, 2005 | 96 | 2005 |
Identification of tomato plant as a novel host model for Burkholderia pseudomallei YH Lee, Y Chen, X Ouyang, YH Gan BMC microbiology 10, 1-11, 2010 | 92 | 2010 |
The Condition-Dependent Transcriptional Landscape of Burkholderia pseudomallei WF Ooi, C Ong, T Nandi, JF Kreisberg, HH Chua, G Sun, Y Chen, ... PLoS genetics 9 (9), e1003795, 2013 | 90 | 2013 |
Flagellin contamination of recombinant heat shock protein 70 is responsible for its activity on T cells Z Ye, YH Gan Journal of Biological Chemistry 282 (7), 4479-4484, 2007 | 88 | 2007 |
Host susceptibility factors to bacterial infections in type 2 diabetes YH Gan PLoS pathogens 9 (12), e1003794, 2013 | 87 | 2013 |
A glycosylated cationic block poly (β‐peptide) reverses intrinsic antibiotic resistance in all ESKAPE gram‐negative bacteria Z Si, HW Lim, MYF Tay, Y Du, L Ruan, H Qiu, R Zamudio‐Vazquez, ... Angewandte Chemie International Edition 59 (17), 6819-6826, 2020 | 84 | 2020 |
Modified Virulence of Antibiotic-Induced Burkholderia pseudomallei Filaments K Chen, GW Sun, KL Chua, YH Gan Antimicrobial agents and chemotherapy 49 (3), 1002-1009, 2005 | 81 | 2005 |
Cell envelope defects of different capsule‐null mutants in K1 hypervirulent Klebsiella pneumoniae can affect bacterial pathogenesis YH Tan, Y Chen, WHW Chu, LT Sham, YH Gan Molecular microbiology 113 (5), 889-905, 2020 | 66 | 2020 |
Host cytosolic glutathione sensing by a membrane histidine kinase activates the type VI secretion system in an intracellular bacterium J Wong, Y Chen, YH Gan Cell host & microbe 18 (1), 38-48, 2015 | 66 | 2015 |