| The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C S Sucic, A El-Kasaby, O Kudlacek, S Sarker, HH Sitte, P Marin, ... Journal of Biological Chemistry 286 (18), 16482-16490, 2011 | 115 | 2011 |
| Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter A El-Kasaby, H Just, E Malle, PC Stolt-Bergner, HH Sitte, M Freissmuth, ... Journal of Biological Chemistry 285 (50), 39201-39210, 2010 | 83 | 2010 |
| Switching the clientele S Sucic, F Koban, A El-Kasaby, O Kudlacek, T Stockner, HH Sitte, ... Journal of Biological Chemistry 288 (8), 5330-5341, 2013 | 64 | 2013 |
| A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter A El-Kasaby, F Koban, HH Sitte, M Freissmuth, S Sucic Journal of Biological Chemistry 289 (42), 28987-29000, 2014 | 52 | 2014 |
| Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism HMM Asjad, A Kasture, A El-Kasaby, M Sackel, T Hummel, M Freissmuth, ... Journal of Biological Chemistry 292 (47), 19250-19265, 2017 | 51 | 2017 |
| A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter F Koban, A El-Kasaby, C Häusler, T Stockner, BM Simbrunner, HH Sitte, ... Journal of Biological Chemistry 290 (21), 13263-13278, 2015 | 51 | 2015 |
| Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones*♦ A Kasture, A El-Kasaby, D Szöllősi, HMM Asjad, A Grimm, T Stockner, ... Journal of Biological Chemistry 291 (40), 20876-20890, 2016 | 48 | 2016 |
| Functional and biochemical consequences of disease variants in neurotransmitter transporters: a special emphasis on folding and trafficking deficits S Bhat, A El-Kasaby, M Freissmuth, S Sucic Pharmacology & therapeutics 222, 107785, 2021 | 47 | 2021 |
| Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome A El-Kasaby, A Kasture, F Koban, M Hotka, HMM Asjad, H Kubista, ... Neuropharmacology 161, 107572, 2019 | 42 | 2019 |
| The creatine transporter unfolded: a knotty premise in the cerebral creatine deficiency syndrome CV Farr, A El-Kasaby, M Freissmuth, S Sucic Frontiers in Synaptic Neuroscience 12, 588954, 2020 | 39 | 2020 |
| Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates S Bhat, PS Hasenhuetl, A Kasture, A El-Kasaby, MH Baumann, ... Journal of Biological Chemistry 292 (40), 16773-16786, 2017 | 36 | 2017 |
| Tropane-based ibogaine analog rescues folding-deficient serotonin and dopamine transporters S Bhat, DA Guthrie, A Kasture, A El-Kasaby, J Cao, A Bonifazi, T Ku, ... ACS Pharmacology & Translational Science 4 (2), 503-516, 2020 | 27 | 2020 |
| The N terminus specifies the switch between transport modes of the human serotonin transporter C Kern, FA Erdem, A El-Kasaby, W Sandtner, M Freissmuth, S Sucic Journal of Biological Chemistry 292 (9), 3603-3613, 2017 | 20 | 2017 |
| Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff C Ranftler, D Nagl, A Sparer, A Röhrich, M Freissmuth, A El-Kasaby, ... PLoS One 16 (5), e0252211, 2021 | 18 | 2021 |
| Functional impact of the G279S substitution in the adenosine A1-receptor (A1R-G279S7. 44), a mutation associated with Parkinson’s disease S Nasrollahi-Shirazi, D Szöllösi, Q Yang, E Muratspahic, A El-Kasaby, ... Molecular pharmacology 98 (3), 250-266, 2020 | 18 | 2020 |
| When transporters fail to be transported: how to rescue folding-deficient SLC6 transporters S Sucic, A Kasture, HMM Asjad, C Kern, A El-Kasaby, M Freissmuth Journal of neurology & neuromedicine 1 (9), 34, 2016 | 14 | 2016 |
| Drosophila melanogaster as a model for unraveling unique molecular features of epilepsy elicited by human GABA transporter 1 variants AS Kasture, FP Fischer, L Kunert, ML Burger, AC Burgstaller, A El-Kasaby, ... Frontiers in Neuroscience 16, 1074427, 2023 | 9 | 2023 |
| Cooperative binding of substrate and ions drives forward cycling of the human creatine transporter-1 CV Farr, A El-Kasaby, FA Erdem, S Sucic, M Freissmuth, W Sandtner Frontiers in Physiology 13, 919439, 2022 | 9 | 2022 |
| Thermal unfolding of the human serotonin transporter: differential effect by stabilizing and destabilizing mutations and cholesterol on thermodynamic and kinetic stability M Ponleitner, D Szöllősi, A El-Kasaby, F Koban, M Freissmuth, T Stockner Molecular Pharmacology 101 (2), 95-105, 2022 | 9 | 2022 |
| (+)-Catharanthine and (-)-18-methoxycoronaridine induce antidepressant-like activity in mice by differently recruiting serotonergic and norepinephrinergic neurotransmission HR Arias, P De Deurwaerdère, A El-Kasaby, G Di Giovanni, S Eom, ... European Journal of Pharmacology 939, 175454, 2023 | 6 | 2023 |
Michael FreissmuthMedical University of ViennaDirección de correo verificada de meduniwien.ac.at
