| Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, ... science 303 (5666), 2011-2015, 2004 | 3870 | 2004 |
| Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 R Mostoslavsky, KF Chua, DB Lombard, WW Pang, MR Fischer, L Gellon, ... Cell 124 (2), 315-329, 2006 | 1916 | 2006 |
| Recent progress in the biology and physiology of sirtuins T Finkel, CX Deng, R Mostoslavsky Nature 460 (7255), 587-591, 2009 | 1771 | 2009 |
| A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy IH Lee, L Cao, R Mostoslavsky, DB Lombard, J Liu, NE Bruns, M Tsokos, ... Proceedings of the National Academy of Sciences 105 (9), 3374-3379, 2008 | 1633 | 2008 |
| SIRT1 regulates circadian clock gene expression through PER2 deacetylation G Asher, D Gatfield, M Stratmann, H Reinke, C Dibner, F Kreppel, ... Cell 134 (2), 317-328, 2008 | 1567 | 2008 |
| Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α Z Gerhart‐Hines, JT Rodgers, O Bare, C Lerin, SH Kim, R Mostoslavsky, ... The EMBO journal 26 (7), 1913-1923, 2007 | 1488 | 2007 |
| Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation DB Lombard, FW Alt, HL Cheng, J Bunkenborg, RS Streeper, ... Molecular and cellular biology 27 (24), 8807-8814, 2007 | 1432 | 2007 |
| SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic β cells MC Haigis, R Mostoslavsky, KM Haigis, K Fahie, DC Christodoulou, ... Cell 126 (5), 941-954, 2006 | 1426 | 2006 |
| Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice HL Cheng, R Mostoslavsky, S Saito, JP Manis, Y Gu, P Patel, R Bronson, ... Proceedings of the National Academy of Sciences 100 (19), 10794-10799, 2003 | 1345 | 2003 |
| The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α L Zhong, A D'Urso, D Toiber, C Sebastian, RE Henry, DD Vadysirisack, ... Cell 140 (2), 280-293, 2010 | 1159 | 2010 |
| DNA repair, genome stability, and aging DB Lombard, KF Chua, R Mostoslavsky, S Franco, M Gostissa, FW Alt Cell 120 (4), 497-512, 2005 | 1120 | 2005 |
| SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging P Oberdoerffer, S Michan, M McVay, R Mostoslavsky, J Vann, SK Park, ... Cell 135 (5), 907-918, 2008 | 985 | 2008 |
| Mechanism and control of V (D) J recombination at the immunoglobulin heavy chain locus D Jung, C Giallourakis, R Mostoslavsky, FW Alt Annu. Rev. Immunol. 24 (1), 541-570, 2006 | 805 | 2006 |
| SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine H Jiang, S Khan, Y Wang, G Charron, B He, C Sebastian, J Du, R Kim, ... Nature 496 (7443), 110-113, 2013 | 792 | 2013 |
| The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism C Sebastián, BMM Zwaans, DM Silberman, M Gymrek, A Goren, L Zhong, ... Cell 151 (6), 1185-1199, 2012 | 729 | 2012 |
| SIRT1 controls endothelial angiogenic functions during vascular growth M Potente, L Ghaeni, D Baldessari, R Mostoslavsky, L Rossig, F Dequiedt, ... Genes & development 21 (20), 2644-2658, 2007 | 719 | 2007 |
| The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun NR Sundaresan, P Vasudevan, L Zhong, G Kim, S Samant, V Parekh, ... Nature medicine 18 (11), 1643-1650, 2012 | 496 | 2012 |
| Interplay between metabolism and epigenetics: a nuclear adaptation to environmental changes JP Etchegaray, R Mostoslavsky Molecular cell 62 (5), 695-711, 2016 | 467 | 2016 |
| Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase V Guarani, G Deflorian, CA Franco, M Krüger, LK Phng, K Bentley, ... Nature 473 (7346), 234-238, 2011 | 416 | 2011 |
| SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling D Toiber, F Erdel, K Bouazoune, DM Silberman, L Zhong, P Mulligan, ... Molecular cell 51 (4), 454-468, 2013 | 410 | 2013 |
David LombardUniversity of MiamiDirección de correo verificada de miami.edu
