Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH J Jasti, H Furukawa, EB Gonzales, E Gouaux Nature 449 (7160), 316-323, 2007 | 1243 | 2007 |
Subunit arrangement and function in NMDA receptors H Furukawa, SK Singh, R Mancusso, E Gouaux Nature 438 (7065), 185-192, 2005 | 1095 | 2005 |
Crystal structure of a heterotetrameric NMDA receptor ion channel E Karakas, H Furukawa Science 344 (6187), 992-997, 2014 | 662 | 2014 |
Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand‐binding core H Furukawa, E Gouaux The EMBO journal, 2003 | 660 | 2003 |
Structure, function, and allosteric modulation of NMDA receptors KB Hansen, F Yi, RE Perszyk, H Furukawa, LP Wollmuth, AJ Gibb, ... Journal of General Physiology 150 (8), 1081-1105, 2018 | 575 | 2018 |
Structure, function, and pharmacology of glutamate receptor ion channels KB Hansen, LP Wollmuth, D Bowie, H Furukawa, FS Menniti, ... Pharmacological reviews 73 (4), 1469-1658, 2021 | 438 | 2021 |
Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors E Karakas, N Simorowski, H Furukawa Nature 475 (7355), 249-253, 2011 | 384 | 2011 |
Structure of the zinc‐bound amino‐terminal domain of the NMDA receptor NR2B subunit E Karakas, N Simorowski, H Furukawa The EMBO journal 28 (24), 3910-3920, 2009 | 258 | 2009 |
Activation of NMDA receptors and the mechanism of inhibition by ifenprodil N Tajima, E Karakas, T Grant, N Simorowski, R Diaz-Avalos, N Grigorieff, ... Nature 534 (7605), 63-68, 2016 | 244 | 2016 |
Mechanism of partial agonist action at the NR1 subunit of NMDA receptors A Inanobe, H Furukawa, E Gouaux Neuron 47 (1), 71-84, 2005 | 233 | 2005 |
Crystal structure and association behaviour of the GluR2 amino‐terminal domain R Jin, SK Singh, S Gu, H Furukawa, AI Sobolevsky, J Zhou, Y Jin, ... The EMBO journal 28 (12), 1812-1823, 2009 | 208 | 2009 |
Control of assembly and function of glutamate receptors by the amino-terminal domain KB Hansen, H Furukawa, SF Traynelis Molecular pharmacology 78 (4), 535-549, 2010 | 153 | 2010 |
The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition K Michalski, JL Syrjanen, E Henze, J Kumpf, H Furukawa, T Kawate Elife 9, e54670, 2020 | 145 | 2020 |
Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motif H Takahashi, Y Shin, SJ Cho, WM Zago, T Nakamura, Z Gu, Y Ma, ... Neuron 53 (1), 53-64, 2007 | 130 | 2007 |
Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors KM Vance, N Simorowski, SF Traynelis, H Furukawa Nature communications 2 (1), 294, 2011 | 104 | 2011 |
Structural basis of functional transitions in mammalian NMDA receptors TH Chou, N Tajima, A Romero-Hernandez, H Furukawa Cell 182 (2), 357-371. e13, 2020 | 102 | 2020 |
A structural biology perspective on NMDA receptor pharmacology and function MC Regan, A Romero-Hernandez, H Furukawa Current opinion in structural biology 33, 68-75, 2015 | 96 | 2015 |
Emerging structural insights into the function of ionotropic glutamate receptors E Karakas, MC Regan, H Furukawa Trends in biochemical sciences 40 (6), 328-337, 2015 | 95 | 2015 |
Structural insights into competitive antagonism in NMDA receptors A Jespersen, N Tajima, G Fernandez-Cuervo, EC Garnier-Amblard, ... Neuron 81 (2), 366-378, 2014 | 95 | 2014 |
Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors KB Hansen, N Tajima, R Risgaard, RE Perszyk, L Jørgensen, KM Vance, ... Molecular pharmacology 84 (1), 114-127, 2013 | 93 | 2013 |