| HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β Q Fang, B Inanc, S Schamus, X Wang, L Wei, AR Brown, D Svilar, ... Nature communications 5 (1), 5513, 2014 | 119 | 2014 |
| Human variants of O6-alkylguanine-DNA alkyltransferase AE Pegg, Q Fang, NA Loktionova DNA repair 6 (8), 1071-1078, 2007 | 86 | 2007 |
| Enzyme mechanism-based, oxidative DNA–protein cross-links formed with DNA polymerase β in vivo JL Quiñones, U Thapar, K Yu, Q Fang, RW Sobol, B Demple Proceedings of the National Academy of Sciences 112 (28), 8602-8607, 2015 | 85 | 2015 |
| Kinetic analysis of steps in the repair of damaged DNA by human O6-alkylguanine-DNA alkyltransferase H Zang, Q Fang, AE Pegg, FP Guengerich Journal of Biological Chemistry 280 (35), 30873-30881, 2005 | 83 | 2005 |
| O 6-Alkylguanine-DNA alkyltransferase: Low p K a and high reactivity of cysteine 145 FP Guengerich, Q Fang, L Liu, DL Hachey, AE Pegg Biochemistry 42 (37), 10965-10970, 2003 | 83 | 2003 |
| Cross-Linking of the DNA Repair Protein O6-Alkylguanine DNA Alkyltransferase to DNA in the Presence of Antitumor Nitrogen Mustards R Loeber, E Michaelson, Q Fang, C Campbell, AE Pegg, N Tretyakova Chemical research in toxicology 21 (4), 787-795, 2008 | 80 | 2008 |
| The repair of the tobacco specific nitrosamine derived adduct O 6-[4-oxo-4-(3-pyridyl) butyl] guanine by O 6-alkylguanine-DNA alkyltransferase variants RS Mijal, NM Thomson, NL Fleischer, GT Pauly, RC Moschel, S Kanugula, ... Chemical research in toxicology 17 (3), 424-434, 2004 | 76 | 2004 |
| Cross-Linking of the Human DNA Repair Protein O6-Alkylguanine DNA Alkyltransferase to DNA in the Presence of 1,2,3,4-Diepoxybutane R Loeber, M Rajesh, Q Fang, AE Pegg, N Tretyakova Chemical research in toxicology 19 (5), 645-654, 2006 | 75 | 2006 |
| Function of domains of human O 6-alkylguanine-DNA alkyltransferase Q Fang, S Kanugula, AE Pegg Biochemistry 44 (46), 15396-15405, 2005 | 74 | 2005 |
| Repair of O6-G-Alkyl-O6-G Interstrand Cross-Links by Human O6-Alkylguanine-DNA Alkyltransferase Q Fang, AM Noronha, SP Murphy, CJ Wilds, JL Tubbs, JA Tainer, ... Biochemistry 47 (41), 10892-10903, 2008 | 61 | 2008 |
| Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase S Bale, MM Lopez, GI Makhatadze, Q Fang, AE Pegg, SE Ealick Biochemistry 47 (50), 13404-13417, 2008 | 52 | 2008 |
| Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis CA Koczor, KM Saville, JF Andrews, J Clark, Q Fang, J Li, ... Cell reports 37 (5), 2021 | 51 | 2021 |
| The base excision repair pathway is required for efficient lentivirus integration KE Yoder, A Espeseth, X Wang, Q Fang, MT Russo, RS Lloyd, D Hazuda, ... PloS one 6 (3), e17862, 2011 | 48 | 2011 |
| DNA Sequence Context Affects Repair of the Tobacco-Specific Adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by Human O6-Alkylguanine-DNA Alkyltransferases RS Mijal, S Kanugula, CC Vu, Q Fang, AE Pegg, LA Peterson Cancer research 66 (9), 4968-4974, 2006 | 41 | 2006 |
| Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations MD Bacolod, SP Johnson, AE Pegg, ME Dolan, RC Moschel, NS Bullock, ... Molecular cancer therapeutics 3 (9), 1127-1135, 2004 | 41 | 2004 |
| Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases Q Fang, S Kanugula, JL Tubbs, JA Tainer, AE Pegg Journal of Biological Chemistry 285 (11), 8185-8195, 2010 | 38 | 2010 |
| Synthesis and characterization of an O 6-2′-deoxyguanosine-alkyl-O 6-2′-deoxyguanosine interstrand cross-link in a 5′-GNC motif and repair by human O 6-alkylguanine-DNA … FP McManus, Q Fang, JDM Booth, AM Noronha, AE Pegg, CJ Wilds Organic & Biomolecular Chemistry 8 (19), 4414-4426, 2010 | 38 | 2010 |
| Substitution of Aminomethyl at the Meta-Position Enhances the Inactivation of O6-Alkylguanine-DNA Alkyltransferase by O6-Benzylguanine GT Pauly, NA Loktionova, Q Fang, SL Vankayala, WC Guida, AE Pegg Journal of medicinal chemistry 51 (22), 7144-7153, 2008 | 36 | 2008 |
| Prevention of chemical carcinogen DNA binding and inhibition of nuclear RNA polymerase activity by organosulfur compounds as the possible mechanisms for their anticancer … FL Yu, W Bender, Q Fang, A Ludeke, B Welch Cancer Detection and Prevention 27 (5), 370-379, 2003 | 33 | 2003 |
| Kinetics of O6-Methyl-2‘-deoxyguanosine Repair by O6-Alkylguanine DNA Alkyltransferase within K-ras Gene-Derived DNA Sequences R Guza, M Rajesh, Q Fang, AE Pegg, N Tretyakova Chemical research in toxicology 19 (4), 531-538, 2006 | 28 | 2006 |
Robert W. Sobol, PhDDepartment of Pathology and Laboratory Medicine & Legorreta Cancer Center at Brown UniversityDirección de correo verificada de brown.edu