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Cancer cell 7 (5), 469-483, 2005
2888 2005 Longevity, stress response, and cancer in aging telomerase-deficient mice KL Rudolph, S Chang, HW Lee, M Blasco, GJ Gottlieb, C Greider, ...
Cell 96 (5), 701-712, 1999
1672 1999 Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice SE Artandi, S Chang, SL Lee, S Alson, GJ Gottlieb, L Chin, RA DePinho
Nature 406 (6796), 641-645, 2000
1382 2000 Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects DA Tuveson, AT Shaw, NA Willis, DP Silver, EL Jackson, S Chang, ...
Cancer cell 5 (4), 375-387, 2004
957 2004 Essential role of limiting telomeres in the pathogenesis of Werner syndrome S Chang, AS Multani, NG Cabrera, ML Naylor, P Laud, D Lombard, ...
Nature genetics 36 (8), 877-882, 2004
538 2004 Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres L Wu, AS Multani, H He, W Cosme-Blanco, Y Deng, JM Deng, O Bachilo, ...
Cell 126 (1), 49-62, 2006
533 2006 Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery KL Rudolph, S Chang, M Millard, N Schreiber-Agus, RA DePinho
Science 287 (5456), 1253-1258, 2000
533 2000 Telomere dysfunction and tumour suppression: the senescence connection Y Deng, SS Chan, S Chang
Nature reviews cancer 8 (6), 450-458, 2008
505 2008 The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations DO Ferguson, JAM Sekiguchi, S Chang, KM Frank, Y Gao, RA DePinho, ...
Proceedings of the National Academy of Sciences 97 (12), 6630-6633, 2000
490 2000 Conformal deformation of metrics on SYA Chang, PC Yang
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458 1988 TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA RL Flynn, RC Centore, RJ O’Sullivan, R Rai, A Tse, Z Songyang, S Chang, ...
Nature 471 (7339), 532-536, 2011
421 2011 IEEE Electron Dev CY Chen, YK Su, SJ Chang, GC Chi, JK Sheu, JF Chen, CH Liu, UH Liaw
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408 2001 Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation J Buis, Y Wu, Y Deng, J Leddon, G Westfield, M Eckersdorff, ...
Cell 135 (1), 85-96, 2008
390 2008 Some weighted norm inequalities concerning the Schrödinger operators SYA Chang, JM Wilson, TH Wolff
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388 1985 Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation KK Wong, S Chang, SR Weiler, S Ganesan, J Chaudhuri, C Zhu, ...
Nature genetics 26 (1), 85-88, 2000
375 2000 Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice G Liu, JM Parant, G Lang, P Chau, A Chavez-Reyes, AK El-Naggar, ...
Nature genetics 36 (1), 63-68, 2004
374 2004 WRN helicase is a synthetic lethal target in microsatellite unstable cancers EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi, N Dumont, ...
Nature 568 (7753), 551-556, 2019
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The EMBO journal 26 (22), 4709-4719, 2007
321 2007 Telomere dysfunction provokes regional amplification and deletion in cancer genomes RC O'Hagan, S Chang, RS Maser, R Mohan, SE Artandi, L Chin, ...
Cancer cell 2 (2), 149-155, 2002
306 2002 Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53‐dependent cellular senescence W Cosme‐Blanco, MF Shen, AJF Lazar, S Pathak, G Lozano, AS Multani, ...
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265 2007