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Christopher A. MacRaild
Christopher A. MacRaild
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Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites
D Richard, CA MacRaild, DT Riglar, JA Chan, M Foley, J Baum, SA Ralph, ...
Journal of Biological Chemistry 285 (19), 14815-14822, 2010
3042010
Applications of 19F-NMR in Fragment-Based Drug Discovery
RS Norton, EWW Leung, IR Chandrashekaran, CA MacRaild
Molecules 21 (7), 860, 2016
1132016
Global changes in local protein dynamics reduce the entropic cost of carbohydrate binding in the arabinose-binding protein
CA MacRaild, AH Daranas, A Bronowska, SW Homans
Journal of molecular biology 368 (3), 822-832, 2007
1032007
A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin
JG Menting, J Gajewiak, CA MacRaild, DHC Chou, MM Disotuar, ...
Nature structural & molecular biology 23 (10), 916-920, 2016
952016
NMR structure of human apolipoprotein C-II in the presence of sodium dodecyl sulfate
CA MacRaild, DM Hatters, GJ Howlett, PR Gooley
Biochemistry 40 (18), 5414-5421, 2001
892001
Structure and activity of (2, 8)-dicarba-(3, 12)-cystino α-ImI, an α-conotoxin containing a nonreducible cystine analogue
CA MacRaild, J Illesinghe, BJ Lierop, AL Townsend, M Chebib, BG Livett, ...
Journal of medicinal chemistry 52 (3), 755-762, 2009
882009
Dicarba α-Conotoxin Vc1.1 Analogues with Differential Selectivity for Nicotinic Acetylcholine and GABAB Receptors
BJ Van Lierop, SD Robinson, SN Kompella, A Belgi, JR McArthur, A Hung, ...
ACS chemical biology 8 (8), 1815-1821, 2013
832013
Antibody recognition of disordered antigens
CA MacRaild, JS Richards, RF Anders, RS Norton
Structure 24 (1), 148-157, 2016
802016
The Structure and Interactions of Human Apolipoprotein C-II in Dodecyl Phosphocholine,
CA MacRaild, GJ Howlett, PR Gooley
Biochemistry 43 (25), 8084-8093, 2004
792004
The circularization of amyloid fibrils formed by apolipoprotein C-II
DM Hatters, CA MacRaild, R Daniels, WS Gosal, NH Thomson, JA Jones, ...
Biophysical journal 85 (6), 3979-3990, 2003
782003
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles
X Xiong, JG Menting, MM Disotuar, NA Smith, CA Delaine, G Ghabash, ...
Nature structural & molecular biology 27 (7), 615-624, 2020
58*2020
Insights into the immunological properties of intrinsically disordered malaria proteins using proteome scale predictions
AJ Guy, V Irani, CA MacRaild, RF Anders, RS Norton, JG Beeson, ...
PLoS One 10 (10), e0141729, 2015
562015
Non-fibrillar components of amyloid deposits mediate the self-association and tangling of amyloid fibrils
CA MacRaild, CR Stewart, YF Mok, MJ Gunzburg, MA Perugini, ...
Journal of Biological Chemistry 279 (20), 21038-21045, 2004
562004
Apical membrane antigen 1 as an anti-malarial drug target
C A MacRaild, R F Anders, M Foley, R S Norton
Current topics in medicinal chemistry 11 (16), 2039-2047, 2011
542011
EGCG disaggregates amyloid-like fibrils formed by Plasmodium falciparum merozoite surface protein 2
IR Chandrashekaran, CG Adda, CA MacRaild, RF Anders, RS Norton
Archives of biochemistry and biophysics 513 (2), 153-157, 2011
512011
Antigenic characterization of an intrinsically unstructured protein, Plasmodium falciparum merozoite surface protein 2
CG Adda, CA MacRaild, L Reiling, K Wycherley, MJ Boyle, V Kienzle, ...
Infection and immunity 80 (12), 4177-4185, 2012
502012
Sedimentation velocity analysis of flexible macromolecules: self-association and tangling of amyloid fibrils
CA MacRaild, DM Hatters, LJ Lawrence, GJ Howlett
Biophysical journal 84 (4), 2562-2569, 2003
492003
Inhibition by Flavonoids of Amyloid-like Fibril Formation by Plasmodium falciparum Merozoite Surface Protein 2
IR Chandrashekaran, CG Adda, CA MacRaild, RF Anders, RS Norton
Biochemistry 49 (28), 5899-5908, 2010
422010
Conformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2
CA MacRaild, M Zachrdla, D Andrew, B Krishnarjuna, J Nováček, L Žídek, ...
PLoS One 10 (3), e0119899, 2015
412015
Ligand-Induced Conformational Change of Plasmodium falciparum AMA1 Detected Using 19F NMR
X Ge, CA MacRaild, SM Devine, CO Debono, G Wang, PJ Scammells, ...
Journal of Medicinal Chemistry 57 (15), 6419-6427, 2014
402014
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