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David Ferrick
David Ferrick
Chief Scientific Officer
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Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
M Wu, A Neilson, AL Swift, R Moran, J Tamagnine, D Parslow, ...
American Journal of Physiology-Cell Physiology 292 (1), C125-C136, 2007
11312007
Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
WC Yeh, A Shahinian, D Speiser, J Kraunus, F Billia, A Wakeham, ...
Immunity 7 (5), 715-725, 1997
10121997
Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo
DA Ferrick, MD Schrenzel, T Mulvania, B Hsieh, WG Ferlin, H Lepper
Nature 373 (6511), 255-257, 1995
8581995
Advances in measuring cellular bioenergetics using extracellular flux
DA Ferrick, A Neilson, C Beeson
Drug discovery today 13 (5-6), 268-274, 2008
5612008
Analysis and interpretation of microplate-based oxygen consumption and pH data
AS Divakaruni, A Paradyse, DA Ferrick, AN Murphy, M Jastroch
Methods in enzymology 547, 309-354, 2014
5602014
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
LS Pike, AL Smift, NJ Croteau, DA Ferrick, M Wu
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1807 (6), 726-734, 2011
5212011
High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria
GW Rogers, MD Brand, S Petrosyan, D Ashok, AA Elorza, DA Ferrick, ...
PloS one 6 (7), e21746, 2011
5062011
The Bioenergetic Health Index: a new concept in mitochondrial translational research
BK Chacko, PA Kramer, S Ravi, GA Benavides, T Mitchell, BP Dranka, ...
Clinical science 127 (6), 367-373, 2014
4062014
Quantitative microplate-based respirometry with correction for oxygen diffusion
AA Gerencser, A Neilson, SW Choi, U Edman, N Yadava, RJ Oh, ...
Analytical chemistry 81 (16), 6868-6878, 2009
3792009
Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo
M Lohoff, D Ferrick, HW Mittrücker, GS Duncan, S Bischof, M Röllinghoff, ...
Immunity 6 (6), 681-689, 1997
3571997
Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier
AS Divakaruni, SE Wiley, GW Rogers, AY Andreyev, S Petrosyan, ...
Proceedings of the national academy of sciences 110 (14), 5422-5427, 2013
3322013
Etomoxir inhibits macrophage polarization by disrupting CoA homeostasis
AS Divakaruni, WY Hsieh, L Minarrieta, TN Duong, KKO Kim, ...
Cell metabolism 28 (3), 490-503. e7, 2018
3262018
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4
M Lohoff, HW Mittrücker, S Prechtl, S Bischof, F Sommer, S Kock, ...
Proceedings of the National Academy of Sciences 99 (18), 11808-11812, 2002
3242002
Identification of a novel selD homolog from Eukaryotes, Bacteria, and Archaea: Is there an autoregulatory mechanism in selenocysteine metabolism?
MJ Guimarães, D Peterson, A Vicari, BG Cocks, NG Copeland, DJ Gilbert, ...
Proceedings of the National Academy of Sciences 93 (26), 15086-15091, 1996
3221996
Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4+ T-cell depletion at all stages of simian immunodeficiency virus infection …
Z Smit-McBride, JJ Mattapallil, M McChesney, D Ferrick, S Dandekar
Journal of virology 72 (8), 6646-6656, 1998
2731998
Bioenergetic profile experiment using C2C12 myoblast cells
DG Nicholls, VM Darley-Usmar, M Wu, PB Jensen, GW Rogers, ...
Journal of Visualized Experiments (JoVE), e2511, 2010
2442010
Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo
DB Conze, L Albert, DA Ferrick, DV Goeddel, WC Yeh, T Mak, JD Ashwell
Molecular and cellular biology 25 (8), 3348-3356, 2005
2292005
Cutting edge: protective response to pulmonary injury requires γδ T lymphocytes
DP King, DM Hyde, KA Jackson, DM Novosad, TN Ellis, L Putney, ...
The Journal of Immunology 162 (9), 5033-5036, 1999
2221999
Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells
M Lohoff, GS Duncan, D Ferrick, HW Mittrücker, S Bischof, S Prechtl, ...
Journal of Experimental Medicine 192 (3), 325-336, 2000
2102000
Analysis of metabolic activity in cells using extracellular flux rate measurements
A Neilson, J Teich, M Wu, D Ferrick
US Patent App. 11/545,714, 2007
1752007
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Artículos 1–20