CAVER Analyst 2.0: analysis and visualization of channels and tunnels in protein structures and molecular dynamics trajectories A Jurcik, D Bednar, J Byska, SM Marques, K Furmanova, L Daniel, ... Bioinformatics 34 (20), 3586-3588, 2018 | 334 | 2018 |
CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures B Kozlikova, E Sebestova, V Sustr, J Brezovsky, O Strnad, L Daniel, ... Bioinformatics 30 (18), 2684-2685, 2014 | 168 | 2014 |
Enzyme tunnels and gates as relevant targets in drug design SM Marques, L Daniel, T Buryska, Z Prokop, J Brezovsky, J Damborsky Medicinal Research Reviews 37 (5), 1095-1139, 2017 | 85 | 2017 |
Exploration of enzyme diversity by integrating bioinformatics with expression analysis and biochemical characterization P Vanacek, E Sebestova, P Babkova, S Bidmanova, L Daniel, P Dvorak, ... Acs Catalysis 8 (3), 2402-2412, 2018 | 81 | 2018 |
Wedelolactone acts as proteasome inhibitor in breast cancer cells T Nehybová, J Šmarda, L Daniel, M Stiborek, V Kanický, I Spasojevič, ... International journal of molecular sciences 18 (4), 729, 2017 | 39 | 2017 |
Wedelolactone induces growth of breast cancer cells by stimulation of estrogen receptor signalling T Nehybova, J Smarda, L Daniel, J Brezovsky, P Benes The Journal of Steroid Biochemistry and Molecular Biology 152, 76-83, 2015 | 39 | 2015 |
Mechanism-Based Discovery of Novel Substrates of Haloalkane Dehalogenases Using in Silico Screening L Daniel, T Buryska, Z Prokop, J Damborsky, J Brezovsky Journal of Chemical Information and Modeling 55 (1), 54-62, 2015 | 38 | 2015 |
Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites R Chaloupkova, T Prudnikova, P Rezacova, Z Prokop, T Koudelakova, ... Acta Crystallographica Section D: Biological Crystallography 70 (7), 1884-1897, 2014 | 38 | 2014 |
Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium Marinobacter sp. ELB17 L Chrast, K Tratsiak, J Planas-Iglesias, L Daniel, T Prudnikova, ... Microorganisms 7 (11), 498, 2019 | 22 | 2019 |
Structure-function relationships and engineering of haloalkane dehalogenases P Kokkonen, T Koudelakova, R Chaloupkova, L Daniel, Z Prokop, ... Aerobic utilization of hydrocarbons, oils and lipids. Cham: Springer …, 2017 | 13 | 2017 |
Discovery of novel haloalkane dehalogenase inhibitors T Buryska, L Daniel, A Kunka, J Brezovsky, J Damborsky, Z Prokop Applied and Environmental Microbiology 82 (6), 1958-1965, 2016 | 12 | 2016 |
Substituted aminothiazoles as inhibitors of nucleases K Paruch, B Carbain, S Havel, J Damborsky, J Brezovsky, L Daniel, ... US Patent 11,584,742, 2023 | 1 | 2023 |
Discovery of new inhibitors of nuclease MRE11 F Nikulenkov, B Carbain, R Biswas, S Havel, J Prochazkova, A Sisakova, ... European Journal of Medicinal Chemistry 285, 117226, 2025 | | 2025 |
ヌクレアーゼの阻害剤としての置換アミノチアゾール K Paruch, BJP Carbain, Š Havel, J Damborský, J Brezovský, L Daniel, ... | | 2022 |
Pyrazolotriazines as inhibitors of nucleases J Damborsky, F Nikulenkov, A Sisakova, S Havel, L Krejci, B Carbain, ... US Patent 9,969,741, 2018 | | 2018 |
Wedelolactone Acts as Proteasome Inhibitor in Breast Cancer Cells T Kučírková, J Šmarda, L Daniel, M Stiborek, V Kanický, I Spasojevič, ... | | 2017 |
Pyrazolotriazines as inhibitors of nucleases K Paruch, B Carbain, Š Havel, J Damborský, J Brezovský, L Daniel, ... | | 2017 |
Pyrazolotriazines as inhibitors of nucleases J Damborsky, F Nikulenkov, A Sisakova, S Havel, L Krejci, B Carbain, ... | | 2015 |
Wedelolactone induces growth of breast cancer cells by stimulation of estrogen receptor signalling T Kučírková, J Šmarda, L Daniel, J Brezovský, P Beneš | | 2015 |
DNA damage response proteins as a pharmacological targets L Krejci, F Nikulenkov, A Sisakova, P Samadder, T Suchankova, ... FEBS JOURNAL 281, 50-50, 2014 | | 2014 |