| A system for stable expression of short interfering RNAs in mammalian cells TR Brummelkamp, R Bernards, R Agami science 296 (5567), 550-553, 2002 | 6905 | 2002 |
| A genomic and functional inventory of deubiquitinating enzymes SMB Nijman, MPA Luna-Vargas, A Velds, TR Brummelkamp, AMG Dirac, ... Cell 123 (5), 773-786, 2005 | 2229 | 2005 |
| Stable suppression of tumorigenicity by virus-mediated RNA interference TR Brummelkamp, R Bernards, R Agami Cancer cell 2 (3), 243-247, 2002 | 1719 | 2002 |
| Ebola virus entry requires the cholesterol transporter Niemann–Pick C1 JE Carette, M Raaben, AC Wong, AS Herbert, G Obernosterer, ... Nature 477 (7364), 340-343, 2011 | 1541 | 2011 |
| A large-scale RNAi screen in human cells identifies new components of the p53 pathway K Berns, EM Hijmans, J Mullenders, TR Brummelkamp, A Velds, ... Nature 428 (6981), 431-437, 2004 | 1477 | 2004 |
| Regulation of progenitor cell proliferation and granulocyte function by microRNA-223 JB Johnnidis, MH Harris, RT Wheeler, S Stehling-Sun, MH Lam, O Kirak, ... Nature 451 (7182), 1125-1129, 2008 | 1458 | 2008 |
| YAP1 increases organ size and expands undifferentiated progenitor cells FD Camargo, S Gokhale, JB Johnnidis, D Fu, GW Bell, R Jaenisch, ... Current biology 17 (23), 2054-2060, 2007 | 1428 | 2007 |
| Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB TR Brummelkamp, SMB Nijman, AMG Dirac, R Bernards Nature 424 (6950), 797-801, 2003 | 1261 | 2003 |
| Yap1 acts downstream of α-catenin to control epidermal proliferation K Schlegelmilch, M Mohseni, O Kirak, J Pruszak, JR Rodriguez, D Zhou, ... Cell 144 (5), 782-795, 2011 | 1154 | 2011 |
| Gene essentiality and synthetic lethality in haploid human cells VA Blomen, P Májek, LT Jae, JW Bigenzahn, J Nieuwenhuis, J Staring, ... Science 350 (6264), 1092-1096, 2015 | 930 | 2015 |
| The cohesin release factor WAPL restricts chromatin loop extension JHI Haarhuis, RH van der Weide, VA Blomen, JO Yáñez-Cuna, ... Cell 169 (4), 693-707. e14, 2017 | 713 | 2017 |
| The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway SMB Nijman, TT Huang, AMG Dirac, TR Brummelkamp, RM Kerkhoven, ... Molecular cell 17 (3), 331-339, 2005 | 703 | 2005 |
| Specific inhibition of gene expression using a stably integrated, inducible small‐interfering‐RNA vector M Van De Wetering, I Oving, V Muncan, MT Pon Fong, H Brantjes, ... EMBO reports 4 (6), 609-615, 2003 | 653 | 2003 |
| Identification of CMTM6 and CMTM4 as PD-L1 protein regulators R Mezzadra, C Sun, LT Jae, R Gomez-Eerland, E De Vries, W Wu, ... Nature 549 (7670), 106-110, 2017 | 639 | 2017 |
| Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure K Segawa, S Kurata, Y Yanagihashi, TR Brummelkamp, F Matsuda, ... Science 344 (6188), 1164-1168, 2014 | 602 | 2014 |
| Haploid genetic screens in human cells identify host factors used by pathogens JE Carette, CP Guimaraes, M Varadarajan, AS Park, I Wuethrich, ... Science 326 (5957), 1231-1235, 2009 | 599 | 2009 |
| Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition AT Das, TR Brummelkamp, EM Westerhout, M Vink, M Madiredjo, ... Journal of virology 78 (5), 2601-2605, 2004 | 577 | 2004 |
| Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension SMA Lens, RMF Wolthuis, R Klompmaker, J Kauw, R Agami, ... The EMBO journal, 2003 | 405 | 2003 |
| Ebola virus entry requires the host‐programmed recognition of an intracellular receptor EH Miller, G Obernosterer, M Raaben, AS Herbert, MS Deffieu, ... The EMBO journal 31 (8), 1947-1960, 2012 | 388 | 2012 |
| Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line P Essletzbichler, T Konopka, F Santoro, D Chen, BV Gapp, R Kralovics, ... Genome research 24 (12), 2059-2065, 2014 | 336 | 2014 |
