| A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome M Scheibye-Knudsen, SJ Mitchell, EF Fang, T Iyama, T Ward, J Wang, ... Cell metabolism 20 (5), 840-855, 2014 | 380 | 2014 |
| Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer A Mangerich, CG Knutson, NM Parry, S Muthupalani, W Ye, E Prestwich, ... Proceedings of the National Academy of Sciences 109 (27), E1820-E1829, 2012 | 274 | 2012 |
| ADP‐ribosyltransferases, an update on function and nomenclature B Lüscher, I Ahel, M Altmeyer, A Ashworth, P Bai, P Chang, M Cohen, ... The FEBS journal 289 (23), 7399-7410, 2022 | 246 | 2022 |
| NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome EF Fang, Y Hou, S Lautrup, MB Jensen, B Yang, T SenGupta, D Caponio, ... Nature communications 10 (1), 5284, 2019 | 226 | 2019 |
| Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation A Mangerich, A Bürkle Oxidative medicine and cellular longevity 2012 (1), 321653, 2012 | 139 | 2012 |
| The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly (ADP-ribosyl) ation of p53 by PARP1 A Fischbach, A Krüger, S Hampp, G Assmann, L Rank, M Hufnagel, ... Nucleic acids research 46 (2), 804-822, 2018 | 117 | 2018 |
| Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease CG Knutson, A Mangerich, Y Zeng, AR Raczynski, RG Liberman, P Kang, ... Proceedings of the National Academy of Sciences 110 (26), E2332-E2341, 2013 | 115 | 2013 |
| How to kill tumor cells with inhibitors of poly (ADP‐ribosyl) ation A Mangerich, A Bürkle International journal of cancer 128 (2), 251-265, 2011 | 115 | 2011 |
| PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression B Dörsam, N Seiwert, S Foersch, S Stroh, G Nagel, D Begaliew, E Diehl, ... Proceedings of the National Academy of Sciences 115 (17), E4061-E4070, 2018 | 100 | 2018 |
| Poly (ADP‐ribose)‐mediated interplay of XPA and PARP 1 leads to reciprocal regulation of protein function JMF Fischer, O Popp, D Gebhard, S Veith, A Fischbach, S Beneke, ... The FEBS journal 281 (16), 3625-3641, 2014 | 94 | 2014 |
| Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease E Prokhorova, T Agnew, AR Wondisford, M Tellier, N Kaminski, D Beijer, ... Molecular cell 81 (12), 2640-2655. e8, 2021 | 86 | 2021 |
| Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1 A Mangerich, N Herbach, B Hanf, A Fischbach, O Popp, ... Mechanisms of ageing and development 131 (6), 389-404, 2010 | 84 | 2010 |
| Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy A Krüger, A Bürkle, K Hauser, A Mangerich Nature communications 11 (1), 2174, 2020 | 78 | 2020 |
| Quantification of cellular poly (ADP-ribosyl) ation by stable isotope dilution mass spectrometry reveals tissue-and drug-dependent stress response dynamics R Martello, A Mangerich, S Sass, PC Dedon, A Burkle ACS chemical biology 8 (7), 1567-1575, 2013 | 77 | 2013 |
| Mechanisms of Hg species induced toxicity in cultured human astrocytes: genotoxicity and DNA-damage response I Pieper, CA Wehe, J Bornhorst, F Ebert, L Leffers, M Holtkamp, P Höseler, ... Metallomics 6 (3), 662-671, 2014 | 70 | 2014 |
| PARP1 catalytic variants reveal branching and chain length-specific functions of poly (ADP-ribose) in cellular physiology and stress response L Aberle, A Krüger, JM Reber, M Lippmann, M Hufnagel, M Schmalz, ... Nucleic Acids Research 48 (18), 10015-10033, 2020 | 69 | 2020 |
| Critical evaluation of human health risks due to hydraulic fracturing in natural gas and petroleum production KM Wollin, G Damm, H Foth, A Freyberger, T Gebel, A Mangerich, ... Archives of Toxicology 94, 967-1016, 2020 | 64 | 2020 |
| Site-specific noncovalent interaction of the biopolymer poly (ADP-ribose) with the Werner syndrome protein regulates protein functions O Popp, S Veith, J Fahrer, VA Bohr, A Bürkle, A Mangerich ACS chemical biology 8 (1), 179-188, 2013 | 58 | 2013 |
| The nucleolus and PARP1 in cancer biology M Engbrecht, A Mangerich Cancers 12 (7), 1813, 2020 | 54 | 2020 |
| Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells F Ebert, L Leffers, T Weber, S Berndt, A Mangerich, S Beneke, A Bürkle, ... Journal of Trace Elements in Medicine and Biology 28 (2), 138-146, 2014 | 53 | 2014 |