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Laura M. Huckins, PhD
Laura M. Huckins, PhD
Associate Professor, Dept of Psychiatry, Yale
Dirección de correo verificada de yale.edu
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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
AF Pardiñas, P Holmans, AJ Pocklington, V Escott-Price, S Ripke, ...
Nature genetics, 1, 2018
16382018
Genome-wide association study identifies 30 loci associated with bipolar disorder
EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ...
Nature genetics 51 (5), 793-803, 2019
15112019
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ...
Science 360 (6395), eaap8757, 2018
14982018
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ...
Nature genetics 53 (6), 817-829, 2021
10922021
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
AN Barbeira, SP Dickinson, R Bonazzola, J Zheng, HE Wheeler, ...
Nature communications 9 (1), 1825, 2018
10152018
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
HJ Watson, Z Yilmaz, LM Thornton, C Hübel, JRI Coleman, HA Gaspar, ...
Nature genetics 51 (8), 1207-1214, 2019
9822019
Genetic analyses of diverse populations improves discovery for complex traits
GL Wojcik, M Graff, KK Nishimura, R Tao, J Haessler, CR Gignoux, ...
Nature 570 (7762), 514-518, 2019
9612019
Mapping the human genetic architecture of COVID-19
CHG Initiative
Nature, 2021
845*2021
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium
Science (New York, NY) 360 (6395), 2018
7072018
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ...
Cell 173 (7), 1705-1715. e16, 2018
5822018
A genome-wide association study of anorexia nervosa
V Boraska, CS Franklin, JAB Floyd, LM Thornton, LM Huckins, L Southam, ...
Molecular psychiatry 19 (10), 1085-1094, 2014
3662014
Whole-genome sequencing reveals host factors underlying critical COVID-19
A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ...
Nature 607 (7917), 97-103, 2022
3072022
Synergistic effects of common schizophrenia risk variants
N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ...
Nature genetics 51 (10), 1475-1485, 2019
2332019
Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four health care systems
AB Zheutlin, J Dennis, R Karlsson Linnér, A Moscati, N Restrepo, ...
American Journal of Psychiatry 176 (10), 846-855, 2019
2192019
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
LM Huckins, A Dobbyn, DM Ruderfer, G Hoffman, W Wang, AF Pardinas, ...
Nature genetics 51 (4), 659-674, 2019
1992019
Machine learning to predict mortality and critical events in a cohort of patients with COVID-19 in New York City: model development and validation
A Vaid, S Somani, AJ Russak, JK De Freitas, FF Chaudhry, I Paranjpe, ...
Journal of medical Internet research 22 (11), e24018, 2020
1962020
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors
N Mullins, JE Kang, AI Campos, JRI Coleman, AC Edwards, H Galfalvy, ...
Biological psychiatry 91 (3), 313-327, 2022
1912022
The genetics of the mood disorder spectrum: genome-wide association analyses of more than 185,000 cases and 439,000 controls
JRI Coleman, HA Gaspar, J Bryois, EM Byrne, AJ Forstner, PA Holmans, ...
Biological psychiatry 88 (2), 169-184, 2020
1692020
Recent genetics and epigenetics approaches to PTSD
NP Daskalakis, CM Rijal, C King, LM Huckins, KJ Ressler
Current psychiatry reports 20, 1-12, 2018
1572018
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS
A Dobbyn, LM Huckins, J Boocock, LG Sloofman, BS Glicksberg, ...
The American Journal of Human Genetics, 2018
1542018
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Artículos 1–20