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Pavel Zhabyeyev, PhD
Pavel Zhabyeyev, PhD
Department of Medicine (Cardiology), University of Alberta
Dirección de correo verificada de ualberta.ca
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Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia‐reperfusion injury: therapeutic potential of synthetic Apelin analogues
W Wang, SMK McKinnie, VB Patel, G Haddad, Z Wang, P Zhabyeyev, ...
Journal of the American Heart Association 2 (4), e000249, 2013
2442013
Role of iron metabolism in heart failure: From iron deficiency to iron overload
H Zhang, P Zhabyeyev, S Wang, GY Oudit
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (7 …, 2019
1962019
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload
P Zhabyeyev, M Gandhi, J Mori, R Basu, Z Kassiri, A Clanachan, ...
Cardiovascular research 97 (4), 676-685, 2013
1742013
Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy
SK Das, W Wang, P Zhabyeyev, R Basu, B McLean, D Fan, N Parajuli, ...
Scientific reports 5 (1), 18132, 2015
1182015
PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease
VB Patel, P Zhabyeyev, X Chen, F Wang, M Paul, D Fan, BA McLean, ...
Nature communications 9 (1), 5390, 2018
672018
Loss of p47phox Subunit Enhances Susceptibility to Biomechanical Stress and Heart Failure Because of Dysregulation of Cortactin and Actin Filaments
VB Patel, Z Wang, D Fan, P Zhabyeyev, R Basu, SK Das, W Wang, ...
Circulation research 112 (12), 1542-1556, 2013
632013
S4153R is a gain-of-function mutation in the cardiac Ca2+ release channel ryanodine receptor associated with catecholaminergic polymorphic ventricular tachycardia and …
P Zhabyeyev, F Hiess, R Wang, Y Liu, SRW Chen, GY Oudit
Canadian Journal of Cardiology 29 (8), 993-996, 2013
432013
Low-affinity block of cardiac K+ currents by nifedipine
P Zhabyeyev, S Missan, SE Jones, TF McDonald
European journal of pharmacology 401 (2), 137-143, 2000
382000
Unravelling the molecular basis for cardiac iron metabolism and deficiency in heart failure
P Zhabyeyev, GY Oudit
European heart journal 38 (5), 373-375, 2017
372017
PI3K inhibitors as novel cancer therapies: implications for cardiovascular medicine
BA McLean, P Zhabyeyev, E Pituskin, I Paterson, MJ Haykowsky, ...
Journal of cardiac failure 19 (4), 268-282, 2013
352013
TIMP3 deficiency exacerbates iron overload-mediated cardiomyopathy and liver disease
P Zhabyeyev, SK Das, R Basu, M Shen, VB Patel, Z Kassiri, GY Oudit
American Journal of Physiology-Heart and Circulatory Physiology 314 (5 …, 2018
322018
Endothelial and cardiomyocyte PI3Kβ divergently regulate cardiac remodelling in response to ischaemic injury
X Chen, P Zhabyeyev, AK Azad, W Wang, RA Minerath, J DesAulniers, ...
Cardiovascular research 115 (8), 1343-1356, 2019
292019
Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy
G Haddad, P Zhabyeyev, M Farhan, LF Zhu, Z Kassiri, DC Rayner, ...
Blood, The Journal of the American Society of Hematology 124 (13), 2142-2149, 2014
272014
Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy
SK Das, P Zhabyeyev, R Basu, VB Patel, JRB Dyck, Z Kassiri, GY Oudit
Bioscience Reports 38 (1), BSR20171302, 2018
222018
PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult …
BA McLean, P Zhabyeyev, VB Patel, R Basu, N Parajuli, J DesAulniers, ...
Cardiovascular research 105 (3), 292-303, 2015
222015
PI3Kα pathway inhibition with doxorubicin treatment results in distinct biventricular atrophy and remodeling with right ventricular dysfunction
BA McLean, VB Patel, P Zhabyeyev, X Chen, R Basu, F Wang, S Shah, ...
Journal of the American Heart Association 8 (9), e010961, 2019
212019
Enhanced recovery from ischemia–reperfusion injury in PI3Kα dominant negative hearts: Investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK …
BA McLean, PC Kienesberger, W Wang, G Masson, P Zhabyeyev, ...
Journal of molecular and cellular cardiology 54, 9-18, 2013
212013
Differences in the effects of urinary incontinence agents S‐oxybutynin and terodiline on cardiac K+ currents and action potentials
SE Jones, LM Shuba, P Zhabyeyev, JR McCullough, TF McDonald
British journal of pharmacology 131 (2), 245-254, 2000
212000
Inactivation of endothelial cell phosphoinositide 3-kinase β inhibits tumor angiogenesis and tumor growth
AK Azad, P Zhabyeyev, B Vanhaesebroeck, G Eitzen, GY Oudit, ...
Oncogene 39 (41), 6480-6492, 2020
192020
Inhibition of PI3Kinase-α is pro-arrhythmic and associated with enhanced late Na+ current, contractility, and Ca2+ release in murine hearts
P Zhabyeyev, B McLean, X Chen, B Vanhaesebroeck, GY Oudit
Journal of molecular and cellular cardiology 132, 98-109, 2019
192019
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